Abstract: The present invention relates to a method and system for obtaining an interaction property between a molecule or biomolecule or particle or bioparticle or nano- or microparticle on the one hand and a target particle on the other hand. The method comprises obtaining potentiometric titration results for a potentiometric measurement during titration of a solution with a titrant, said solution being a solution of one of a ligand of the target particle or said molecule or biomolecule or particle or bioparticle or nano- or microparticle. Said titrant comprises the other of said target particle ligand or said molecule or biomolecule or particle or bioparticle or nano- or microparticle. The method also comprises deriving based on said potentiometric titration results an interaction property between said molecule or biomolecule or particle or bioparticle or nano- or microparticle and said target particle.

Abstract: A compensation device for compensating PVT variations of an analog and/or digital circuit. The compensation device includes a transistor having a first terminal, a second terminal, a third terminal, and a fourth terminal allowing to modify a threshold voltage of the transistor. The transistor is configured to be in saturation region. The voltage at the third terminal has a predetermined value and the difference between the voltage at the second terminal and the voltage at the third terminal has a predetermined value. A current generation module is configured to generate a current of a predetermined value. A compensation module is configured to force this current to flow between the first terminal and the third terminal by adjusting the voltage of the fourth terminal.

Abstract: A compensation device for compensating PVT variations of an analog and/or digital circuit. The compensation device includes a transistor having a first terminal, a second terminal, a third terminal, and a fourth terminal allowing to modify a threshold voltage of the transistor. The transistor is configured to be in saturation region. The voltage at the third terminal has a predetermined value and the difference between the voltage at the second terminal and the voltage at the third terminal has a predetermined value. A current generation module is configured to generate a current of a predetermined value. A compensation module is configured to force this current to flow between the first terminal and the third terminal by adjusting the voltage of the fourth terminal.

Abstract: The present invention relates to a method and system for obtaining an interaction property between a molecule or biomolecule or particle or bioparticle or nano- or microparticle on the one hand and a target particle on the other hand. The method comprises obtaining potentiometric titration results for a potentiometric measurement during titration of a solution with a titrant, said solution being a solution of one of a ligand of the target particle or said molecule or biomolecule or particle or bioparticle or nano- or microparticle. Said titrant comprises the other of said target particle ligand or said molecule or biomolecule or particle or bioparticle or nano- or microparticle. The method also comprises deriving based on said potentiometric titration results an interaction property between said molecule or biomolecule or particle or bioparticle or nano- or microparticle and said target particle.

Abstract: The present invention relates to a potentiometric electrode and gradient polymer, both comprising electrically conducting particles, which increase in concentration away from one surface, ionophore molecules, which increase in concentration towards the same surface surface, and an electrical connection which passes proximal to said electrically conducting particles. The invention further relates to devices incorporating said electrode or gradient polymer, and to a method for their preparation. The new materials are highly robust and reliable.

Abstract: The present invention relates to a potentiometric electrode and gradient polymer, both comprising electrically conducting particles, which increase in concentration away from one surface, ionophore molecules, which increase in concentration towards the same surface surface, and an electrical connection which passes proximal to said electrically conducting particles. The invention further relates to devices incorporating said electrode or gradient polymer, and to a method for their preparation. The new materials are highly robust and reliable.