Patents by Inventor Luc Nelles

Luc Nelles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antagonists of IL17C for the treatment of inflammatory disorders
    Patent number: 10815297
    Abstract: The present invention provides antagonists of IL17C for use in the treatment of an inflammatory disorder.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: October 27, 2020
    Assignees: MORPHOSYS AG, GALAPAGOS NV
    Inventors: Andreas Bültmann, Robert Mühlbacher, Teresa Garcia, Reginald Christophe Xavier Brys, Luc Nelles, Katja Conrath
  • ANTAGONISTS OF IL17C FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20190062422
    Abstract: The present invention provides antagonists of IL17C for use in the treatment of an inflammatory disorder.
    Type: Application
    Filed: November 8, 2018
    Publication date: February 28, 2019
    Inventors: Andreas BÜLTMANN, Robert MÜHLBACHER, Teresa GARCIA, Reginald Christophe Xavier BRYS, Luc NELLES, Katja CONRATH
  • Methods and means for treatment of osteoarthritis
    Patent number: 9951337
    Abstract: The invention relates to the field of medicinal research, cartilage physiology and diseases involving the degeneration of cartilage tissue. More specifically, the invention relates to methods and means for identifying compounds that inhibit catabolic processes in chondrocytes and that decrease the degradation of cartilage and/or ECM. The invention also relates to the compounds that are useful in the treatment of osteoarthritis. The invention also relates to targets, the modulation of which results in a decrease in the degradation of ECM and/or cartilage and decrease inflammation. In addition, the invention relates to compositions and methods for the use thereof in treating conditions that are characterized by the degradation of ECM and/or cartilage and inflammation.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: April 24, 2018
    Assignee: GALAPAGOS NV
    Inventors: Reginald Christophe Xavier Brys, Luc Nelles, Nick Ernest Rene Vandeghinste, Blandine Mille-Baker, Michela Angela Tessari
  • Methods and Means for Treatment of Osteoarthritis
    Publication number: 20160208266
    Abstract: The invention relates to the field of medicinal research, cartilage physiology and diseases involving the degeneration of cartilage tissue. More specifically, the invention relates to methods and means for identifying compounds that inhibit catabolic processes in chondrocytes and that decrease the degradation of cartilage and/or ECM. The invention also relates to the compounds that are useful in the treatment of osteoarthritis. The invention also relates to targets, the modulation of which results in a decrease in the degradation of ECM and/or cartilage and decrease inflammation. In addition, the invention relates to compositions and methods for the use thereof in treating conditions that are characterized by the degradation of ECM and/or cartilage and inflammation.
    Type: Application
    Filed: February 3, 2016
    Publication date: July 21, 2016
    Inventors: Reginald Christophe Xavier Brys, Luc Nelles, Nick Ernest Rene Vandeghinste, Blandine Mille-Baker, Michela Angela Tessari
  • ANTAGONISTS OF IL17C FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20140243506
    Abstract: The present invention provides antagonists of IL17C for use in the treatment of an inflammatory disorder.
    Type: Application
    Filed: October 19, 2012
    Publication date: August 28, 2014
    Inventors: Andreas Bültmann, Robert Mühlbacher, Teresa Garcia, Reginald Christophe Xavier Brys, Luc Nelles, Katja Conrath
  • Methods and Means for Treatment of Osteoarthritis
    Publication number: 20140200258
    Abstract: The invention relates to the field of medicinal research, cartilage physiology and diseases involving the degeneration of cartilage tissue. More specifically, the invention relates to methods and means for identifying compounds that inhibit catabolic processes in chondrocytes and that decrease the degradation of cartilage and/or ECM. The invention also relates to the compounds that are useful in the treatment of osteoarthritis. The invention also relates to targets, the modulation of which results in a decrease in the degradation of ECM and/or cartilage and decrease inflammation. In addition, the invention relates to compositions and methods for the use thereof in treating conditions that are characterized by the degradation of ECM and/or cartilage and inflammation.
    Type: Application
    Filed: January 24, 2014
    Publication date: July 17, 2014
    Inventors: Reginald Christophe Xavier Brys, Luc Nelles, Nick Ernest Rene Vandeghinste, Blandine Mille-Baker, Michela Angela Tessari
  • Methods and means for treatment of osteoarthritis
    Patent number: 8663930
    Abstract: The invention relates to the field of medicinal research, cartilage physiology and diseases involving the degeneration of cartilage tissue. More specifically, the invention relates to methods and means for identifying compounds that inhibit catabolic processes in chondrocytes and that decrease the degradation of cartilage and/or ECM. The invention also relates to the compounds that are useful in the treatment of osteoarthritis. The invention also relates to targets, the modulation of which results in a decrease in the degradation of ECM and/or cartilage and decrease inflammation. In addition, the invention relates to compositions and methods for the use thereof in treating conditions that are characterized by the degradation of ECM and/or cartilage and inflammation.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: March 4, 2014
    Assignee: Galapagos NV
    Inventors: Reginald Christophe Xavier Brys, Luc Nelles, Nick Ernest Rene Vandeghinste, Blandine Mille-Baker, Michela Angela Tessari
  • METHODS AND MEANS FOR TREATMENT OF OSTEOARTHRITIS
    Publication number: 20120027766
    Abstract: The invention relates to the field of medicinal research, cartilage physiology and diseases involving the degeneration of cartilage tissue. More specifically, the invention relates to methods and means for identifying compounds that inhibit catabolic processes in chondrocytes and that decrease the degradation of cartilage and/or ECM. The invention also relates to the compounds that are useful in the treatment of osteoarthritis. The invention also relates to targets, the modulation of which results in a decrease in the degradation of ECM and/or cartilage and decrease inflammation. In addition, the invention relates to compositions and methods for the use thereof in treating conditions that are characterized by the degradation of ECM and/or cartilage and inflammation.
    Type: Application
    Filed: April 1, 2010
    Publication date: February 2, 2012
    Inventors: Reginald Christophe Xavier Brys, Luc Nelles, Nick Ernest Rene Vandeghinste, Blandine Mille-Baker, Michela Angela Tessari