Patents by Inventor Luca Benatti

Luca Benatti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treatment of parkinson's disease
    Publication number: 20070093495
    Abstract: New uses of safinamide, safinamide derivatives and MAO-B inhibitors in novel types of treatment for Parkinson's Disease are described. More specifically, the invention relates to methods for treating Parkinson's Disease through the administration of safinamide, a safinamide derivative, or a MAO-B inhibitor, in combination with other Parkinson's Disease agents or treatments, such as levodopa/PDI or dopamine agonists.
    Type: Application
    Filed: April 8, 2004
    Publication date: April 26, 2007
    Inventors: Fariello Ruggero, Carlo Cattaneo, Patricia Salvati, Luca Benatti
  • Halothenoyl-cyclopropane-1-carboxylic acid derivatives
    Publication number: 20060116329
    Abstract: Compounds of formula (I) wherein R is hydroxy, linear or branched C1-C6 alkoxy, phenoxy, benzyloxy, a group —N(R1R2) wherein R1 is hydrogen, linear or branched C1-C4 alkyl, benzyl, phenyl and R2 is hydrogen or linear or branched C1-C4 alkyl, or R is a glycoside residue or a primary alkoxy residue from ascorbic acid, optionally having one or more hydroxy groups alkylated or acylated by linear or branched C1-C4 alkyl or acyl groups; X is a halogen atom and n 1 or 2 are long lasting inhibitors of kynurenine 3-monooxygenase (KMO) and potent glutamate (GLU) release inhibitors.
    Type: Application
    Filed: November 25, 2003
    Publication date: June 1, 2006
    Inventors: Luca Benatti, Ruggero Fariello, Patricia Salvati, Roberto Pellicciari, Carla Caccia
  • Recombinant KAT enzyme and process for its preparation
    Patent number: 6136572
    Abstract: Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of:(a) isolated DNA sequences which encode rat KAT;(b) an isolated DNA sequence which hybridizes to isolated DNA sequences of (a) above and which encodes a mammalian KAT enzyme; and(c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme.Vectors and host cells containing the same, oligonucleotide probes for identifying kynurenine aminotransferase, and isolated and purified kynurenine aminotransferase are also disclosed.
    Type: Grant
    Filed: April 1, 1997
    Date of Patent: October 24, 2000
    Assignees: University of Maryland at Baltimore, Pharmacia & Upjohn S.P.A.
    Inventors: Luca Benatti, Jerome Breton, Carmela Speciale, Etsuo Okuno, Robert Schwarcz, Monica Mosca
  • Recombinant kynurenine-3-hydroxylase enzyme and process for its preparation
    Patent number: 6107069
    Abstract: The present invention provides an isolated polynucleotide encoding for the kynurenine-3-hydrolase (Kyn-3-OHase) and methods of transiently expressing thereof.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: August 22, 2000
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Simona Magagnin, Luca Benatti, Massimo Cini, Carmela Speciale, Nevie Covini
  • Recombinant kat enzyme from rat
    Patent number: 5817496
    Abstract: Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of: (a) an isolated DNA sequence which encodes rat KAT; (b) an isolated DNA sequence which hybridizes to the isolated DNA sequence of (a) above and which encodes a KAT enzyme; and (c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme. Also disclosed are vectors and host cells containing the same; oligonucleotide probes for identifying kynurenine aminotransferase; and isolated and purified kynurenine aminotransferase.
    Type: Grant
    Filed: July 7, 1994
    Date of Patent: October 6, 1998
    Assignees: Pharmacia & UpJohn S.P.A., University of Maryland at Baltimore
    Inventors: Luca Benatti, Jerome Breton, Carmela Speciale, Etsuo Okuno, Robert Schwarcz, Monica Mosca
  • Isolated DNA encoding a plant ribosome inactivating protein from the leaves of saponaria officinalis
    Patent number: 5529932
    Abstract: Nucleic acid encoding the ribosome-inactivating protein SO-6 is provided.
    Type: Grant
    Filed: October 7, 1993
    Date of Patent: June 25, 1996
    Assignee: Pharmacia, S.p.A.
    Inventors: Rolando Lorenzetti, Luca Benatti, Maria Dian, Douglas Lappi, Maria B. Saccardo, Marco Soria