Patents by Inventor Luca Comai
Luca Comai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120079628Abstract: The present invention provides compositions and methods for modulating cell division in plants. In particular, the present invention provides polynucleotides that encode REVOLUTA. In addition, REVOLUTA vectors and transformed plants are provided wherein plant cell division is modulated by expression of a REVOLUTA transgene as compared to a control population of untransformed plants. The present invention also provides methods for the isolation and identification of REVOLUTA genes from higher plants.Type: ApplicationFiled: September 23, 2011Publication date: March 29, 2012Applicant: University of WashingtonInventors: Ann Joan SLADE, Linda Madisen, Luca Comai
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Publication number: 20110004965Abstract: The present invention provides compositions and methods for modulating cell division in plants. In particular, the present invention provides polynucleotides that encode REVOLUTA. In addition, REVOLUTA vectors and transformed plants are provided wherein plant cell division is modulated by expression of a REVOLUTA transgene as compared to a control population of untransformed plants. The present invention also provides methods for the isolation and identification of REVOLUTA genes from higher plants.Type: ApplicationFiled: March 30, 2010Publication date: January 6, 2011Inventors: Ann Joan SLADE, Linda Madisen, Luca Comai
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Patent number: 7816139Abstract: The present invention provides compositions and methods for modulating cell division in plants. In particular, the present invention provides polynucleotides that encode REVOLUTA. In addition, REVOLUTA vectors and transformed plants are provided wherein plant cell division is modulated by expression of a REVOLUTA transgene as compared to a control population of untransformed plants. The present invention also provides methods for the isolation and identification of REVOLUTA genes from higher plants.Type: GrantFiled: May 25, 2006Date of Patent: October 19, 2010Assignee: University of WashingtonInventors: Ann Slade, Linda Madisen, Luca Comai
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Publication number: 20060218676Abstract: The present invention provides compositions and methods for modulating cell division in plants. In particular, the present invention provides polynucleotides that encode REVOLUTA. In addition, REVOLUTA vectors and transformed plants are provided wherein plant cell division is modulated by expression of a REVOLUTA transgene as compared to a control population of untransformed plants. The present invention also provides methods for the isolation and identification of REVOLUTA genes from higher plants.Type: ApplicationFiled: May 25, 2006Publication date: September 28, 2006Applicant: University of WashingtonInventors: Ann Slade, Linda Madisen, Luca Comai
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Patent number: 7056739Abstract: The present invention provides compositions and methods for modulating cell division in plants. In particular, the present invention provides polynucleotides that encode REVOLUTA. In addition, REVOLUTA vectors and transformed plants are provided wherein plant cell division is modulated by expression of a REVOLUTA transgene as compared to a control population of untransformed plants. The present invention also provides methods for the isolation and identification of REVOLUTA genes from higher plants.Type: GrantFiled: November 10, 2000Date of Patent: June 6, 2006Assignee: University of WashingtonInventors: Ann Joan Slade, Linda Madisen, Luca Comai
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Publication number: 20060031967Abstract: The present invention provides compositions and methods for modulating cell division in plants. In particular, the present invention provides polynucleotides that encode REVOLUTA. In addition. REVOLUTA vectors and transformed plants are provided wherein plant cell division is modulated by expression of a REVOLUTA transgene as compared to a control population of untransformed plants. The present invention also provides methods for the isolation and identification of REVOLUTA genes from higher plants.Type: ApplicationFiled: July 1, 2005Publication date: February 9, 2006Inventors: Ann Slade, Linda Madisen, Luca Comai
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Patent number: 6774283Abstract: Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.Type: GrantFiled: November 23, 1999Date of Patent: August 10, 2004Assignee: Calgene LLCInventors: Robert M. Goodman, Vic C. Knauf, Catherine M. Houck, Luca Comai
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Publication number: 20010049830Abstract: Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.Type: ApplicationFiled: April 7, 1999Publication date: December 6, 2001Inventors: ROBERT M. GOODMAN, VIC C. KNAUF, CATHERINE HOUCK, LUCA COMAI
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Patent number: 6096547Abstract: Constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.Type: GrantFiled: July 31, 1998Date of Patent: August 1, 2000Assignee: Calgene, LLCInventors: Robert M. Goodman, Vic C. Knauf, Catherine M. Houck, Luca Comai
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Patent number: 6051753Abstract: This invention relates to a novel plant promoter derived from the figwort mosaic virus and methods of use of same.Type: GrantFiled: December 4, 1992Date of Patent: April 18, 2000Assignee: Calgene, Inc.Inventors: Luca Comai, Margaret P. Sanger, Stephen Daniel Daubert
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Patent number: 5629175Abstract: Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.Type: GrantFiled: June 5, 1995Date of Patent: May 13, 1997Assignee: Calgene, Inc.Inventors: Robert M. Goodman, Vic C. Knauf, Catherine M. Houck, Luca Comai
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Patent number: 5550038Abstract: Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.Type: GrantFiled: December 8, 1993Date of Patent: August 27, 1996Assignee: Calgene, Inc.Inventors: Robert M. Goodman, Vic C. Knauf, Catherine M. Houck, Luca Comai
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Patent number: 5187267Abstract: Novel nucleic acid sequences, constructs employing such sequences, transgenic plant cells and plants are provided employing sequences associated with tomato heat shock protein 80.5 ("hsp80"). Nucleic acid sequences obtainable from the use of hsp80 as a probe in other plant species are also disclosed. In particular, the 5' noncoding region of tomato hsp80 or other plant promoters obtainable therefrom, especially to provide differentially specific initiation of transcription of a desired nucleic acid sequence of interest. Also provided are putative sequences believed to represent Scaffold Attachment Regions (SAR) of the plant hsp80 gene.Type: GrantFiled: June 19, 1990Date of Patent: February 16, 1993Assignee: Calgene, Inc.Inventors: Luca Comai, Ann J. Koning
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Patent number: 5106739Abstract: Unexpectedly high levels of expression of coding sequences can be obtained by the use of a CaMv 35s enhanced mannopine synthase promoter in plant host cells.Type: GrantFiled: February 7, 1990Date of Patent: April 21, 1992Assignee: Calgene, Inc.Inventors: Luca Comai, Paul M. Moran
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Patent number: 5094945Abstract: Enhanced resistance to glyphosate, an inhibitor of the aromatic amino acid biosynthesis pathway, is imparted to a glyphosate sensitive host. A mutated aroA gene is employed which expresses 5-enolpyruvyl-3-phosphoshikimate synthase (EC: 2.5.1.19) (ES-3-P synthase). Methods are provided for obtaining the aroA mutation which provides the enzyme resistant to inhibition by glyphosate, means for introducing the structural gene into a sensitive host, as well as providing a method of producing the enzyme.The E. coli strain C600 (pPMG1) has been deposited at the A.T.C.C. on December 14, 1982 and given A.T.C.C. Accession No. 39256.Type: GrantFiled: August 30, 1988Date of Patent: March 10, 1992Assignee: Calgene, Inc.Inventor: Luca Comai
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Patent number: 5068193Abstract: Method and compositions are provided for introducing alien DNA into a nucleic acid in vivo by providing a plasmid capable of replication in a first host, which is capable of conjugation with a second host into which the alien DNA is to be introduced. The plasmid is characterized by being capable of maintenance in said first host, being incapable of maintenance in said second host, having a region of homology with DNA present in said second host, not self-transmissable but capable of mobilization by a helper plasmid and having a marker, which may be the alien DNA, for selection in said second host. The invention finds particular application for introducing alien DNA into the Ti plasmid of Agrobacterium tumefaciens for introduction into plant cells.Type: GrantFiled: May 11, 1988Date of Patent: November 26, 1991Assignee: Calgene, Inc.Inventor: Luca Comai
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Patent number: 4956282Abstract: Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.Type: GrantFiled: July 29, 1985Date of Patent: September 11, 1990Assignee: Calgene, Inc.Inventors: Robert M. Goodman, Vic C. Knauf, Catherine M. Houck, Luca Comai
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Patent number: 4795855Abstract: Woody species, particularly poplar, are produced by transformation of shoot cultures with the foreign DNA and regeneration of plants from transformed cells, where the plants are capable of expression of the foreign gene. Particularly, poplar shoot cultures are employed and are transformed employing a manipulated Agrobacterium transformation system, followed by regeneration of the plant tissue into plants.Type: GrantFiled: February 24, 1986Date of Patent: January 3, 1989Inventors: Joanne Fillatti, Luca Comai
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Patent number: 4769061Abstract: Enhanced resistance to glyphosate, an inhibitor of the aromatic amino acid biosynthesis pathway, is imparted to a glyphosate sensitive host. A mutated aroA gene is employed which expresses 5-enolpyruvyl-3- phosphoshikimate synthase (EC: 2.5.1.19) (ES-3-P synthase). Methods are provided for obtaining the aroA mutation which provides the enzyme resistant to inhibition by glyphosate, means for introducing the structural gene into a sensitive host, as well as providing a method of producing the enzyme.The E. coli strain C600(pPMG1) has been deposited at the A.T.C.C. on Dec. 14, 1982 and given A.T.C.C. Accession No. 39256.Type: GrantFiled: February 4, 1985Date of Patent: September 6, 1988Assignee: Calgene Inc.Inventor: Luca Comai
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Patent number: 4762785Abstract: Method and compositions are provided for introducing alien DNA into a nucleic acid in vivo by providing a plasmid capable of replication in a first host, which is capable of conjugation with a second host into which the alien DNA is to be introducted. The plasmid is characterized by being capable of maintenance in said first host, being incapable of maintenance in said second host, having a region of homology with DNA present in said second host, not self-transmissable but capable of mobilization by a helper plasmid and having a marker, which may be the alien DNA, for selection in said second host. The invention finds particular application for introducing alien DNA into the Ti plasmid of Agrobacterium tumefaciens for introduction into plant cells.Type: GrantFiled: November 6, 1985Date of Patent: August 9, 1988Assignee: Calgene, Inc.Inventor: Luca Comai