Abstract: The present disclosure is directed to compositions including a VLDLR-based decoy receptor as, as well as methods of use for preventing and treating alphavirus infection in a subject in need thereof. Compositions of the VLDLR-based decoy receptor include an Fc domain and at least one VLDLR LA domain. A subject in need thereof includes a subject having or at risk for contracting an alphavirus infection selected from at least one of Eastern equine encephalitis virus (EEEV), Chikungunya virus (CHIKV), and Venezuelan equine encephalitis virus (VEEV) infection.

Abstract: A gloss scoring system includes: a camera configured to capture an image of a surface of an object; a gloss score module configured to determine a gloss score value corresponding to a glossiness of the surface of the object based on: a representation of the image; stored representations of images stored in memory; and stored gloss value scores associated with the stored representations, respectively; and a display control module configured to display on a display the image and the gloss score value corresponding to the glossiness of the surface of the object.

Abstract: Disclosed herein are embodiments of systems, methods, and products comprises a server for efficiently processing electronic requests. The server receives a plurality of predictive computer models and a specification file for each model for registration. The server extracts validation codes for each model based on the specification file. When the server receives an electronic request, the API layer of the server validates the request by verifying the inputs of the request satisfying the validation codes of the corresponding model. If the electronic request is invalid, the server returns an error message immediately; otherwise, the API layer of the server sends the electronic request to the model execution layer. Within the model execution layer, the server executes the corresponding model based on the request inputs and generates output results. The model execution layer transmits the output results back to the API layer, which transmits the output results to the user device.

Abstract: The present invention relates to antibodies or antigen-binding fragments that are useful for treating coronavirus infections (e.g., COVID-19 caused by SARS-CoV-2). The present invention also relates to various pharmaceutical compositions and methods of treating coronavirus using the antibodies or antigen-binding fragments.

Abstract: Disclosed herein are embodiments of systems, methods, and products comprises a server for efficiently processing electronic requests. The server receives a plurality of predictive computer models and a specification file for each model for registration. The server extracts validation codes for each model based on the specification file. When the server receives an electronic request, the API layer of the server validates the request by verifying the inputs of the request satisfying the validation codes of the corresponding model. If the electronic request is invalid, the server returns an error message immediately; otherwise, the API layer of the server sends the electronic request to the model execution layer. Within the model execution layer, the server executes the corresponding model based on the request inputs and generates output results. The model execution layer transmits the output results back to the API layer, which transmits the output results to the user device.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating a user interface that includes a viewport space of a digital content item; generating, based on user input, breakpoints of the viewport space based on a height, a width, or an aspect ratio of the viewport space; based on the breakpoints, generating formatting rules that each create a different version of the digital content item when the formatting rule is applied; and distributing, to a client device, the digital content item for display within an electronic document, including providing i) text or image content of the digital content item and ii) the formatting rules, wherein the formatting rules cause a client-side application to dynamically render and display an appropriate version of the digital content item based on the formatting rules and a size of a display area in which the digital content item is presented.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating a user interface that includes a viewport space of a digital content item; generating, based on user input, breakpoints of the viewport space based on a height, a width, or an aspect ratio of the viewport space; based on the breakpoints, generating formatting rules that each create a different version of the digital content item when the formatting rule is applied; and distributing, to a client device, the digital content item for display within an electronic document, including providing i) text or image content of the digital content item and ii) the formatting rules, wherein the formatting rules cause a client-side application to dynamically render and display an appropriate version of the digital content item based on the formatting rules and a size of a display area in which the digital content item is presented.

Abstract: A method, apparatus and computer program product are provided for generation, selection, and execution of metric applications. An example of the method includes receiving, via record access circuitry, the set of record data from a record repository, determining, by a processor and from the set of record data, record key data and one or more record data tables for the set of record data, selecting, by metric management circuitry, one or more metric applications based on a mapping performed between record key data and a metric registration structure, wherein the metric registration structure comprises metric application metadata indicating data types required by each of a plurality of metric applications, executing, by a processor, each of the selected one or more metric applications, determining an output of each of the executed selected one or more metric applications, and storing the output in a memory.

Abstract: A method, apparatus and computer program product are provided for generation, selection, and execution of metric applications. An example of the method includes receiving, via record access circuitry, the set of record data from a record repository, determining, by a processor and from the set of record data, record key data and one or more record data tables for the set of record data, selecting, by metric management circuitry, one or more metric applications based on a mapping performed between record key data and a metric registration structure, wherein the metric registration structure comprises metric application metadata indicating data types required by each of a plurality of metric applications, executing, by a processor, each of the selected one or more metric applications, determining an output of each of the executed selected one or more metric applications, and storing the output in a memory.

Abstract: A control system for a machine is disclosed. The control system may have a power source, an operator input device configured to generate a first signal indicative of a desired mode of power source operation, and a work implement driven by the power source. The control system may also have a controller in communication with the power source and the operator input device. The controller may be configured to classify a currently performed work implement task and select an output map based on the classification of the currently performed work implement task and the first signal. The controller may further be configured to control the power source operation using the output map.

Abstract: An automatic shut down system for a machine having an engine and a work implement is disclosed. The automatic shut down system may have a position sensor, which may be associated with the work implement. The position sensor may be configured to generate a position signal indicative of a position of the work implement. The automatic shut down system may also have a controller, which may be in communication with the position sensor. The controller may be configured to shut down the engine, based on the position signal.

Abstract: A control system for a machine is disclosed. The control system may have a power source, an operator input device, a work implement, and a controller in communication with the power source and the operator input device. The operator input device may be configured to generate a signal indicative of a desired mode of power source operation. The work implement may be driven by the power source to accomplish a task. The controller may be configured to classify a currently performed task, and adjust power source operation based on the task signal and the classification.

Abstract: An automatic shut down system for a machine having an engine and a work implement is disclosed. The automatic shut down system may have a position sensor, which may be associated with the work implement. The position sensor may be configured to generate a position signal indicative of a position of the work implement. The automatic shut down system may also have a controller, which may be in communication with the position sensor. The controller may be configured to shut down the engine, based on the position signal.

Abstract: A system for releasing an article such as a munition or store from an aircraft employs a sway brace or cradle built into the structure of a bomb rack from lateral or pitching motion before it is released. A claw mechanism is driven out of the sway braces into the article to hold the article in place on the sway braces. The claws retain the article in the sway braces until the article is no longer influenced by the sway braces.

Abstract: A control system for a machine is disclosed. The control system may have a power source, an operator input device configured to generate a first signal indicative of a desired mode of power source operation, and a work implement driven by the power source. The control system may also have a controller in communication with the power source and the operator input device. The controller may be configured to classify a currently performed work implement task and select an output map based on the classification of the currently performed work implement task and the first signal. The controller may further be configured to control the power source operation using the output map.

Abstract: A control system for a machine is disclosed. The control system may have a power source, an operator input device, a work implement, and a controller in communication with the power source and the operator input device. The operator input device may be configured to generate a signal indicative of a desired mode of power source operation. The work implement may be driven by the power source to accomplish a task. The controller may be configured to classify a currently performed task, and adjust power source operation based on the task signal and the classification.