Patents by Inventor Lucas Liu

Lucas Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250188172
    Abstract: Provided herein are, inter alia, antibody binding domains for cluster of differentiation 3 T cell receptor (CD3), antibody binding domains for epidermal growth factor receptor (EGFR), cleavable linker sequences, and protease-activatable bispecific fusion proteins such as protease-activatable T cell engagers, as well as uses and methods of treatment.
    Type: Application
    Filed: February 25, 2025
    Publication date: June 12, 2025
    Inventors: Viktoriya Dubrovskaya, Eric Johansen, Sina Khorsand, Lucas Liu, Volker Schellenberger, Milton To, Tracy Young, André Frenzel, Philipp Kuhn
  • Publication number: 20250188184
    Abstract: Provided herein are, inter alia, antigen-binding molecules with binding specificity to cluster of differentiation 3 T cell receptor (CD3), antigen-binding molecules with binding specificity to prostate-specific membrane antigen (PSMA), cleavable linker sequences, and protease-activatable bispecific fusion proteins such as protease-activatable T cell engagers, as well as uses and methods of treatment.
    Type: Application
    Filed: February 25, 2025
    Publication date: June 12, 2025
    Inventors: Viktoriya Dubrovskaya, Eric Johansen, Lucas Liu, Darragh MacCann, Volker Schellenberger, Milton To
  • Publication number: 20240400696
    Abstract: Provided herein are, inter alia, antibody binding domains for cluster of differentiation 3 T cell receptor (CD3), antibody binding domains for epidermal growth factor receptor (EGFR), cleavable linker sequences, and protease-activatable bispecific fusion proteins such as protease-activatable T cell engagers, as well as uses and methods of treatment.
    Type: Application
    Filed: April 16, 2024
    Publication date: December 5, 2024
    Inventors: Viktoriya Dubrovskaya, Eric Johansen, Sina Khorsand, Lucas Liu, Volker Schellenberger, Milton To, Tracy Young, André Frenzel, Philipp Kuhn
  • Publication number: 20240327538
    Abstract: Provided herein are, inter alia, antigen-binding molecules with binding specificity to cluster of differentiation 3 T cell receptor (CD3), antigen-binding molecules with binding specificity to prostate-specific membrane antigen (PSMA), cleavable linker sequences, and protease-activatable bispecific fusion proteins such as protease-activatable T cell engagers, as well as uses and methods of treatment.
    Type: Application
    Filed: February 9, 2024
    Publication date: October 3, 2024
    Inventors: Viktoriya Dubrovskaya, Eric Johansen, Lucas Liu, Darragh MacCann, Volker Schellenberger, Milton To
  • Publication number: 20240281705
    Abstract: The disclosed concepts relate to pretraining of machine learning models. One example method involves performing separate optimization of a first machine learning model and a second machine learning model. The first machine learning model can be optimized based at least on first predictions and the second machine learning model can be optimized based at least on second predictions. The first predictions can represent predictions of masked values in first sequences of values values, and the second predictions can represent whether or not the first values were replaced with different values predicted by the first machine learning model.
    Type: Application
    Filed: June 21, 2023
    Publication date: August 22, 2024
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Xiaodong LIU, Chengyu DONG, Lucas LIU, Hao CHENG, Jianfeng GAO
  • Publication number: 20230303267
    Abstract: An autonomous vehicle includes a chassis for housing an aircraft ground contacting structure (GCS) and one or more GCS coupling and lifting mechanisms, GCS securing mechanisms, drivetrain, batteries and a sensor stack for performing autonomous navigation. Further, the vehicle incorporates multiple sensors, such as high-resolution machine vision cameras, GPS modules, Lidars, ultrasonic range sensors, and radars. The sensors deliver spatial perception capabilities to the vehicle and feed relevant data to onboard computing units to achieve location-based navigation, precision alignment with aircraft, obstacle detection and collision avoidance capabilities. A series of batteries deliver power to all components, including but not limited to, motors, electromechanical units, onboard computers, sensors and any other component requiring electrical input. External ports allow the vehicle to recharge batteries after each utilization cycle without replacement.
    Type: Application
    Filed: February 15, 2023
    Publication date: September 28, 2023
    Inventors: Javier Vidal Rojas, Saunon Rod Malekshahi, Andrew Arnold, Dimitrios Bailas, Atanaz Bohlooli, Camille Carr, Orhan Elam, Dima Fayyad, Marc Jabbour, Lucas Liu, Berke Ozdemir, Vedant Singh, Philipp Haban, Matthew Derkach
  • Patent number: 11521409
    Abstract: An approach for determining similar text documents. The approach can calculate a first set of vectors for a first cluster of text documents and a first comparison vector for a text document of interest. The approach can select a subset of text documents from the cluster of text documents based on comparing the vectors from the first set of vectors to the first comparison vector and picking a predetermined number of closest comparison text documents. The approach can calculate a second set of vectors for the subset of documents and second comparison vector for the document of interest. The approach can generate similarity ratings for the subset of documents based on pairwise comparisons of the second comparison vector and the second set of vectors. The approach can generate a ranked list of the second cluster of text documents based on the similarity ratings.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: December 6, 2022
    Assignee: International Business Machines Corporation
    Inventors: Rachel Tzoref-Brill, Lucas Liu, Brian Midei, Dagmawi Sraj, Thomas North Adams, Tianqiong Wang
  • Publication number: 20220327310
    Abstract: An approach for determining similar text documents. The approach can calculate a first set of vectors for a first cluster of text documents and a first comparison vector for a text document of interest. The approach can select a subset of text documents from the cluster of text documents based on comparing the vectors from the first set of vectors to the first comparison vector and picking a predetermined number of closest comparison text documents. The approach can calculate a second set of vectors for the subset of documents and second comparison vector for the document of interest. The approach can generate similarity ratings for the subset of documents based on pairwise comparisons of the second comparison vector and the second set of vectors. The approach can generate a ranked list of the second cluster of text documents based on the similarity ratings.
    Type: Application
    Filed: April 9, 2021
    Publication date: October 13, 2022
    Inventors: Rachel Tzoref-Brill, Lucas Liu, Brian Midei, Dagmawi Sraj, Thomas North Adams, Tianqiong Wang