Patents by Inventor Lucas Nivon

Lucas Nivon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • De novo designed non-local beta sheet proteins
    Patent number: 11802141
    Abstract: Beta-sheet forming polypeptides at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS:1-24 are disclosed, together with their use and methods for designing beta-sheet forming polypeptides.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: October 31, 2023
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Tamuka Chidyausiku, Enrique Marcos, Lucas Nivon, Gustav Oberdorfer, David Baker, Lauren Carter
  • De Novo Designed Non-Local Beta Sheet Proteins
    Publication number: 20210122793
    Abstract: Beta-sheet forming polypeptides at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS:1-24 are disclosed, together with their use and methods for designing beta-sheet forming polypeptides.
    Type: Application
    Filed: October 23, 2020
    Publication date: April 29, 2021
    Inventors: Tamuka CHIDYAUSIKU, Enrique MARCOS, Lucas NIVON, Gustav OBERDORFER, David BAKER, Lauren CARTER
  • Methods and compositions for protein labeling using lipoic acid ligases
    Patent number: 9284541
    Abstract: The present disclosure provides compositions and methods of use thereof for labeling peptide and proteins in vitro or in vivo. The methods described herein employ lipoic acid ligase or mutants thereof, and lipoic acid analogs (e.g., lipoic acid analogs comprising a resorufin moiety) recognized by lipoic acid ligase and lipoic acid ligase mutants. Also provided herein is a method of imaging protein-protein interaction via a reaction mediated by lipoic acid ligase.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: March 15, 2016
    Assignees: Massachusetts Institute of Technology, University of Washington through its Center for Commercialization
    Inventors: Alice Y. Ting, David Baker, Florian Richter, Lucas Nivon, Daniel Shao-Chen Liu
  • METHODS AND COMPOSITIONS FOR PROTEIN LABELING USING LIPOIC ACID LIGASES
    Publication number: 20120129159
    Abstract: The present disclosure provides compositions and methods of use thereof for labeling peptide and proteins in vitro or in vivo. The methods described herein employ lipoic acid ligase or mutants thereof, and lipoic acid analogs (e.g., lipoic acid analogs comprising a resorufin moiety) recognized by lipoic acid ligase and lipoic acid ligase mutants. Also provided herein is a method of imaging protein-protein interaction via a reaction mediated by lipoic acid ligase.
    Type: Application
    Filed: October 6, 2011
    Publication date: May 24, 2012
    Inventors: Alice Y. Ting, David Baker, Florian Richter, Lucas Nivon, Daniel Shao-Chen Liu