Patents by Inventor Lucia A. Frittitta

Lucia A. Frittitta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphic human PC-1 sequences associated with insulin resistance
    Patent number: 6465185
    Abstract: A novel polymorphism in the human PC-1 gene is characterized, which is associated with an increased predisposition to developing insulin resistance. The polymorphism affects heterozygous and homozygous carriers of the allele. The subject nucleic acids and fragments thereof, encoded polypeptides, and antibodies specific for the polymorphic amino acid sequence are useful in determining a genetic predisposition to insulin resistance. The encoded protein is useful in drug screening for compositions that affect the activity of PC-1 and insulin receptor activity or expression.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: October 15, 2002
    Assignees: Instituto di Ricovero e Cura a Carattere Scientifico, The Regents of the University of California
    Inventors: Ira Goldfine, Vincenzo Trischitta, Riccardo Vigneri, Antonio Pizzuti, Lucia A. Frittitta