Patents by Inventor Lucia Beviglia

Lucia Beviglia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating melanoma
    Patent number: 9480744
    Abstract: Methods of inhibiting melanoma tumor growth, methods of treating melanoma and metastatic melanoma, and methods of reducing the frequency of tumor initiating cells (or cancer stem cells) in melanoma tumors are described. The methods described comprise administering a DLL4 antagonist (e.g., an antibody that specifically binds the extracellular domain of human DLL4) to a subject. Related polypeptides and polynucleotides, compositions comprising the DLL4 antagonists, and methods of making the DLL4 antagonists are also described.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: November 1, 2016
    Assignee: OncoMed Pharmaceuticals, Inc.
    Inventors: Timothy C. Hoey, Lucia Beviglia
  • Methods for Treating Melanoma
    Publication number: 20140065149
    Abstract: Methods of inhibiting melanoma tumor growth, methods of treating melanoma and metastatic melanoma, and methods of reducing the frequency of tumor initiating cells (or cancer stem cells) in melanoma tumors are described. The methods described comprise administering a DLL4 antagonist (e.g., an antibody that specifically binds the extracellular domain of human DLL4) to a subject. Related polypeptides and polynucleotides, compositions comprising the DLL4 antagonists, and methods of making the DLL4 antagonists are also described.
    Type: Application
    Filed: September 6, 2013
    Publication date: March 6, 2014
    Applicant: OncoMed Pharmaceuticals, Inc.
    Inventors: Timothy C. HOEY, Lucia Beviglia
  • Methods for treating melanoma
    Patent number: 8551479
    Abstract: Methods of inhibiting melanoma tumor growth, methods of treating melanoma and metastatic melanoma, and methods of reducing the frequency of tumor initiating cells (or cancer stem cells) in melanoma tumors are described. The methods described comprise administering a DLL4 antagonist (e.g., an antibody that specifically binds the extracellular domain of human DLL4) to a subject. Related polypeptides and polynucleotides, compositions comprising the DLL4 antagonists, and methods of making the DLL4 antagonists are also described.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: October 8, 2013
    Assignee: OncoMed Pharmaceuticals, Inc.
    Inventors: Timothy C. Hoey, Lucia Beviglia
  • Methods for Treating Melanoma
    Publication number: 20120070438
    Abstract: Methods of inhibiting melanoma tumor growth, methods of treating melanoma and metastatic melanoma, and methods of reducing the frequency of tumor initiating cells (or cancer stem cells) in melanoma tumors are described. The methods described comprise administering a DLL4 antagonist (e.g., an antibody that specifically binds the extracellular domain of human DLL4) to a subject. Related polypeptides and polynucleotides, compositions comprising the DLL4 antagonists, and methods of making the DLL4 antagonists are also described.
    Type: Application
    Filed: September 9, 2011
    Publication date: March 22, 2012
    Applicant: OncoMed Pharmaceuticals, Inc.
    Inventors: Timothy C. Hoey, Lucia Beviglia