Patents by Inventor Luciano Paulino Da Silva

Luciano Paulino Da Silva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLANT DERIVED ANTIBIOTIC PEPTIDE RICH IN GLYCINE
    Publication number: 20110190197
    Abstract: The present invention relates to a novel peptide extracted from guava (Psidium guajava) seeds, that provides bactericide activity, Preferentially against Gram-negative bacteria which are known to cause urinary, hospital, and intestinal tract infections (Proteus sp. And Klebsiella sp.). The peptide, that has the amino acid sequence RESPSSRMEC YEQAERYGYG GYGGGRYGGG YGSGRGQPVG QGVERSHDDN RNQPR, belongs to the class of glycine rich proteins and has approximately 5 kDa of molecular weight. The invention also relates to antibiotic compositions for human, veterinary and plant treatments. Alternatively, the peptide, or a functionally similar derivative, subjects of the present invention, can be used for transforming organisms aiming pathogen resistance, other adaptive advantages, as well as various properties, specially for plants and animals.
    Type: Application
    Filed: January 2, 2008
    Publication date: August 4, 2011
    Applicants: UBEC & UCB, Empresa Brasileira de Pesquisa Agropecuaria - EMBRAPA
    Inventors: Octavio Luiz Franco, Patrícia Barbosa Pelegrini, Carlos Bloch Junior, Luciano Paulino da Silva
  • Cationic peptides of the phylloseptin family isolated from the skin secretion of
    Patent number: 7371720
    Abstract: The present invention relates to a class of anti-microbial peptides, called Phyllosepti ns, isolated from Phyllomedusa hypochondrialis. The invention also relates to therapeutic and agricultural compositions comprising one or more Phylloseptins. Methods of treating infections of various mammalian organs such as the skin and methods of treating plant infections are also included in the invention.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: May 13, 2008
    Assignees: Empressa Brasileira de Pesquisa Agropecuaria - Embrapa, Fundacao Universidade de Brasilia
    Inventors: Genaro Ribeiro De Paiva, Carlos Bloch Júnior, José Roberto de Souza De Almeida Leite, Luciano Paulino Da Silva
  • Cationic peptides of the dermaseptin family isolated from the skin secretion of phyllomedusa hypochondrialis
    Publication number: 20040242488
    Abstract: This invention is related to anti-microbial peptides having the same amino acid sequence and at least the same anti-microbial activity as those of Phylloseptins which are isolated from the skin of Phyllomedusa hypochondrialis. The peptides did not have any structural homology with another known peptide. The 19-residue anti-microbial peptides are cationic and based on their primary structure, all peptides can be fitted to an amphiphilic a-helix. The peptide masses analyzed by mass spectrometry were in the range of 1.9 to 2.0 kDa. These peptides can be used in compositions for retarding plant pathogens and for protecting plants from pathogens, comprising at least one antibiotic peptide and an agriculturally acceptable carrier. Another embodiment of the invention is to provide therapeutic compositions suitable for human, veterinary, or pharmaceutical use, comprising one or more of the peptides released in this invention and an adequate pharmacological carrier.
    Type: Application
    Filed: July 2, 2004
    Publication date: December 2, 2004
    Inventors: Genaro Ribeiro De Paiva, Carlos Bloch Junior, Jose Roberto de Souza De Almeida Leite, Luciano Paulino da Silva