Patents by Inventor Lucie Fransen

Lucie Fransen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7258861
    Abstract: The present invention is based on the finding that peptides derived from a specific domain of tumor necrosis factor-alpha (TNF-?) can efficiently be used to treat oedema. More specifically, the present invention relates to the usage of peptides derived from the region of human TNF-? from Ser100 to Glu116 to treat pulmonary oedema. For example, the circularized peptide having amino acid sequence CGQRETPEGAEAKPWYC is shown to be very efficient in inducing oedema resorption.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: August 21, 2007
    Assignee: Innogenetics N.V.
    Inventors: Rudolf Lucas, Patrick De Baetselier, Jérôme Pugin, Alain Bloc, Lucie Fransen
  • Publication number: 20030185791
    Abstract: The present invention is based on the finding that peptides derived from a specific domain of tumor necrosis factor-alpha (TNF-&agr;) can efficiently be used to treat oedema. More specifically, the present invention relates to the usage of peptides derived from the region of human TNF-&agr; from Ser100 to Glu116 to treat pulmonary oedema. For example, the circularized peptide having amino acid sequence CGQRETPEGAEAKPWYC is shown to be very efficient in inducing oedema resorption.
    Type: Application
    Filed: June 6, 2002
    Publication date: October 2, 2003
    Inventors: Rudolf Lucas, Patrick De Baetselier, Jerome Pugin, Alain Bloc, Lucie Fransen
  • Publication number: 20030105021
    Abstract: The present invention relates to the finding that peptides derived from a specific domain of tumor necrosis factor-alpha (TNF-&agr;) can efficiently be used to treat oedema. More specifically, the present invention relates to the usage of peptides derived from the region of human TNF-&agr; from Ser100 to Glu116 to treat pulmonary oedema. Moreover, the present invention concerns a circularized peptide having amino acid sequence CGQRETPEGAEAKPWYC which is very efficient in inducing oedema resorption.
    Type: Application
    Filed: February 9, 2001
    Publication date: June 5, 2003
    Inventors: Rudolf Lucas, Patrick De Baetselier, Jerome Pugin, Alain Bloc, Lucie Fransen