Abstract: A thrombolysis catheter apparatus is disclosed comprising: (a) an elongated thrombolysis catheter portion comprising a plurality of independently controllable electroactive polymer actuators, which provide a curvature to the thrombolysis catheter based upon received control signals; (b) a control unit coupled to the plurality of actuators and sending the control signals to the plurality of actuators; and (c) an occlusion removal device. Also disclosed is a method of treating an arterial occlusion by advancing the thrombolysis catheter portion through the arterial vasculature of a patient to a position proximate the occlusion, while controlling the shape of the thrombolysis catheter portion using the control unit. The occlusion is then removed using the occlusion removal device.

Abstract: An endoscope is provided which comprises an elongated body adapted for insertion into a body lumen, and a plurality of electrically controlled actuators associated with the body which are controllable to impart an orientation to the body that is complimentary to the natural orientation of the lumen into which the endoscope is inserted.

Abstract: A novel capture device apparatus comprising: (a) a capture device portion, at least a part of which is adaptable for insertion into a patient and (b) a control unit. The capture device portion comprises one or more apertures and one or more electroactive polymer actuators that open and close the one or more apertures based on control signals sent from the control unit. In another aspect of the present invention, a method of capturing a specimen within a patient's body of provided. The method comprises (a) providing a capture device apparatus like that above, (b) inserting at least a portion of the capture device portion of the apparatus into the patient such that the capture device portion is adjacent the specimen; and (c) closing the one or more apertures using the control unit, thereby capturing the specimen.

Abstract: An endoscope is provided which comprises an elongated body adapted for insertion into a body lumen, and a plurality of electrically controlled actuators associated with the body which are controllable to impart an orientation to the body that is complimentary to the natural orientation of the lumen into which the endoscope is inserted.

Abstract: The present invention is an integrated and automated irrigation and aspiration system for use in an endoscopic imaging system. The system provides for the automated cleaning of poorly prepared patients during a colonoscopy procedure as well as automated cleaning of an imaging system of an endoscope. The invention analyzes images obtained from an image sensor to detect the presence of an obstructed field of view, whereupon a wash routine is initiated to remove the obstruction. The wash routine may be adjusted in accordance with environmental conditions within the patient that are sensed by one or more sensors within the endoscope. In another embodiment, insufflation is automatically controlled to inflate a patient's colon as a function of one or more sensor readings obtained from one or more environmental sensor(s) on the endoscope.

Abstract: The present invention is an integrated and automated irrigation and aspiration system for use in an endoscopic imaging system. The system provides for the automated cleaning of poorly prepared patients during a colonoscopy procedure as well as automated cleaning of an imaging system of an endoscope. The invention analyzes images obtained from an image sensor to detect the presence of an obstructed field of view, whereupon a wash routine is initiated to remove the obstruction. The wash routine may be adjusted in accordance with environmental conditions within the patient that are sensed by one or more sensors within the endoscope. In another embodiment, insufflation is automatically controlled to inflate a patient's colon as a function of one or more sensor readings obtained from one or more environmental sensor(s) on the endoscope.

Abstract: An endoscopic imaging system includes a reusable control cabinet having a number of actuators that control the orientation of a lightweight endoscope that is connectable thereto. The endoscope is used with a single patient and is then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet. The endoscope is coated with a hydrophilic coating that reduces its coefficient of friction and because it is lightweight, requires less force to advance it to a desired location within a patient.

Abstract: A pump apparatus, which comprises: (a) a tubular portion comprising an electroactive polymer actuator that expands and contracts an inner volume of the tubular portion based upon received control signals; and (b) a control unit electrically coupled to the electroactive polymer actuator and sending control signals to the actuator. The pump apparatus can further include at least one valve that is in fluid communication with the inner volume of the tubular portion. The pump apparatus can be used, for example, as a heart-lung bypass pump apparatus. Also disclosed herein is a method of providing circulatory support for patient.

Abstract: An endoscopic imaging system for examining a patient's body cavity includes an endoscope having a distal end, a proximal end and a number of lumens therein. One or more distal gas ports are disposed at or adjacent the distal end of the endoscope and one or more proximal gas ports are disposed proximal to the distal gas ports. Insufflation gas is delivered to the distal gas ports and withdrawn from the proximal gas ports or vice versa such that a gas bubble is formed in the body cavity and travels with the distal tip of the endoscope.

Abstract: A system, device and method for serializing and authorizing a single use imaging device are provided. In one embodiment, the invention provides a single use imaging device comprising a memory having a stored code that includes a unique serial identifier. In another embodiment, the invention provides a system for authorizing a single use imaging device comprising a single use imaging device with an image of a verification object that includes a serial identifier uniquely associated with the device, a control unit capable of electronically receiving the verification object image, a decoder capable of extracting a serial identifier from the verification object image, a database of authorized serial identifiers, and means for determining if the single use imaging device is authorized.

Abstract: A guide catheter apparatus that comprises the following: (a) a guide catheter portion that includes a plurality of electroactive polymer actuators disposed along its axial length and (b) a control unit coupled to the actuators and sending control signals to the actuators. The actuators change the shape of the guide catheter portion based upon the control signals that are received from the control unit. In another aspect of the present invention, a method of introducing a guide catheter into a body lumen is provided. The method comprises: (a) providing a guide catheter apparatus like that above, and (b) inserting the guide catheter portion of the guide catheter apparatus into the body lumen, while using the control unit to control the shape of the guide catheter portion.

Abstract: An endoscope apparatus and method of operating the same. The endoscope apparatus comprises an endoscope portion and a control and display unit. The endoscope portion preferably comprises: (i) a sensor disposed at a distal end of the endoscope portion and providing endoscope data; (ii) one or more electronically controlled actuators (e.g., electroactive polymer actuators) controlling the operation of the endoscope portion based on received control signals; (iii) a first wireless transceiver coupled to the sensor and the one or more electronically controlled actuators, transmitting received endoscope data from the sensor and forwarding received control signals to the one or more electronically controlled actuators; and (iv) a portable power source (e.g., a battery) coupled to the sensor, the first wireless transceiver, and the one or more electronically controller actuators.

Abstract: An ultrasonic imaging catheter apparatus and a method of using the same to scan the inner wall of a body lumen. The ultrasonic imaging catheter apparatus comprises: (a) a flexible elongate element adapted for insertion into a body lumen, the elongate element having distal and proximal ends; (b) an ultrasonic transducer generating and detecting ultrasonic energy disposed proximate the distal end of the elongate element; (c) a reflective member disposed proximate the ultrasonic transducer and optionally rotatable with respect to an axis of the body lumen, wherein the reflective member is adapted to reflect (i) ultrasonic energy generated by the ultrasonic transducer to a wall of the body lumen and (ii) ultrasonic energy reflected by the wall back to the transducer; and (d) an actuator, for example, an electroactive polymer actuator, adapted to change the angle of incidence of the ultrasonic energy relative to the reflective member.

Abstract: A novel capture device apparatus comprising: (a) a capture device portion, at least a part of which is adaptable for insertion into a patient and (b) a control unit. The capture device portion comprises one or more apertures and one or more electroactive polymer actuators that open and close the one or more apertures based on control signals sent from the control unit. In another aspect of the present invention, a method of capturing a specimen within a patient's body of provided. The method comprises (a) providing a capture device apparatus like that above, (b) inserting at least a portion of the capture device portion of the apparatus into the patient such that the capture device portion is adjacent the specimen; and (c) closing the one or more apertures using the control unit, thereby capturing the specimen.

Abstract: A guide catheter apparatus that comprises the following: (a) a guide catheter portion that includes a plurality of electroactive polymer actuators disposed along its axial length and (b) a control unit coupled to the actuators and sending control signals to the actuators. The actuators change the shape of the guide catheter portion based upon the control signals that are received from the control unit. In another aspect of the present invention, a method of introducing a guide catheter into a body lumen is provided. The method comprises: (a) providing a guide catheter apparatus like that above, and (b) inserting the guide catheter portion of the guide catheter apparatus into the body lumen, while using the control unit to control the shape of the guide catheter portion.

Abstract: An endoscope is provided which comprises an elongated body adapted for insertion into a body lumen, and a plurality of electrically controlled actuators associated with the body which are controllable to impart an orientation to the body that is complimentary to the natural orientation of the lumen into which the endoscope is inserted.

Abstract: An endoscope apparatus and method of operating the same. The endoscope apparatus comprises an endoscope portion and a control and display unit. The endoscope portion preferably comprises: (i) a sensor disposed at a distal end of the endoscope portion and providing endoscope data; (ii) one or more electronically controlled actuators (e.g., electroactive polymer actuators) controlling the operation of the endoscope portion based on received control signals; (iii) a first wireless transceiver coupled to the sensor and the one or more electronically controlled actuators, transmitting received endoscope data from the sensor and forwarding received control signals to the one or more electronically controlled actuators; and (iv) a portable power source (e.g., a battery) coupled to the sensor, the first wireless transceiver, and the one or more electronically controller actuators.

Abstract: A guide catheter apparatus that comprises the following: (a) a guide catheter portion that includes a plurality of electroactive polymer actuators disposed along its axial length and (b) a control unit coupled to the actuators and sending control signals to the actuators. The actuators change the shape of the guide catheter portion based upon the control signals that are received from the control unit. In another aspect of the present invention, a method of introducing a guide catheter into a body lumen is provided. The method comprises: (a) providing a guide catheter apparatus like that above, and (b) inserting the guide catheter portion of the guide catheter apparatus into the body lumen, while using the control unit to control the shape of the guide catheter portion.

Abstract: A noninvasive, continuous monitoring device for measuring intraocular pressure without interference with vision or normal activity of the patient. A miniature, planar-faced pressure transducer is fixed in a protruding section of a compliant hydrogel ring which has been tooled to conform to the spherical surface of the sclera. The hydrogel ring is placed noninvasively under the eyelids within the conjunctival cul-de-sac, the transducer being located in the lower temperal quadrant. Applanation of the sclera against the planar surface of the transducer results as a consequence of pressure from the separated tissues. Intraocular pressure readings are based on the variations in resistance in the strain gage elements of the transducer caused by the applied stress to the transducer diaphragm. Data is transmitted through connecting wires to a telemetry unit which transmits the data to a receiver-transcriber console.