Patents by Inventor Lucille Pourcel

Lucille Pourcel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXPRESSION SYSTEMS, RECOMBINANT CELLS AND USES THEREOF
    Publication number: 20230193341
    Abstract: A transcriptomic analysis of genes consistently upregulated in high producer clones were each evaluated for their ability to increase the production of a protein of interest. The products of these genes (metabolism influencing products (MIP)), such as actin, Erp27, Erp57, Foxa1, PPAR, Ca3, and Tagap, could be sub-categorized into different functional categories such as signaling, protein folding, cytoskeleton organization and cell survival.
    Type: Application
    Filed: October 23, 2019
    Publication date: June 22, 2023
    Applicant: Selexis SA
    Inventors: Lucille Pourcel, Audrey Berger, Valerie Le Fourn, Severine Fagete, David Calabrese, Alexandre Regamey, Nicolas Mermod, Fabien Palazzoli, Pierre-Alain Girod
  • USE OF VITAMINS AND VITAMIN METABOLIC GENES AND PROTEINS FOR RECOMBINANT PROTEIN PRODUCTION IN MAMMALIAN CELLS
    Publication number: 20180066268
    Abstract: Disclosed are eukaryotic expression systems and methods for the selection of mammalian cell lines that produce proteins of interest, such as therapeutic proteins. The systems and methods allow for a simple and fast selection of cells mediating high levels of recombinant protein production. The systems and methods decrease the efforts and time needed to bring a new therapeutic protein to the patients, and also lower the cost of the therapeutic protein by increasing the productivity of cells in a bioreactor.
    Type: Application
    Filed: April 1, 2016
    Publication date: March 8, 2018
    Inventors: Nicolas Mermod, Lucille Pourcel, Pierre-Alain Girod, Valerie Le Fourn