Patents by Inventor Lucrezia Guida

Lucrezia Guida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adenyl dinucleotides with antitumour activity and a method of preparing thereof
    Patent number: 7868163
    Abstract: The invention relates to novel adenyl dinucleotides which are isomers of the dinucleotide Ap2A, having formulae (I) and (II). The dinucleotides of the invention have antitumour activity, particularly against tumours of haematological origin, such as for example leukaemias and lymphomas. The invention further relates to the use of such dinucleotides as antitumour medicaments. Finally, the invention relates to an enzymatic method for preparing the dinucleotides of formulae (I) and (II) and to an enzymatic assay method for the dinucleotide of formula (I) which is based on its complete conversion to NAD+.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: January 11, 2011
    Assignees: Universita' Degli Studi Di Genova, Centro Biotecnologie Avanzate
    Inventors: Giovanna Basile, Umberto Benatti, Santina Bruzzone, Gianluca Damonte, Antonio De Flora, Ernesto Fattorusso, Luisa Franco, Lucrezia Guida, Orazio Taglialatela-Scafati, Elena Zocchi
  • Fluridone as an anti-inflammatory agent
    Patent number: 7786042
    Abstract: The invention relates to a novel use of fluridone—compound known per se and used as an aquatic erbicide—in the medical field, in particular as an active compound for preparing a medicament having anti-inflammatory activity. Pharmaceutical compositions comprising fluridone as an active compound and pharmaceutically acceptable carriers and/or diluents are also disclosed. Finally, there is disclosed the pro-inflammatory activity of abscisic acid (ABA), a plant hormone which is also found in mammal serum and against which fluridone acts an inhibitor.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: August 31, 2010
    Assignee: Universita' Degli Studi Di Genova
    Inventors: Elena Zocchi, Lucrezia Guida, Santina Bruzzone, Sonia Scarfi′, Mirko Magnone, Giovanna Basile, Umberto Benatti, Antonio De Flora, Iliana Moreschi, Luisa Franco, Annalisa Salis
  • Fluridone as an Anti-Inflammatory Agent
    Publication number: 20080242705
    Abstract: The invention relates to a novel use of fluridone—compound known per se and used as an aquatic erbicide—in the medical field, in particular as an active compound for preparing a medicament having anti-inflammatory activity. Pharmaceutical compositions comprising fluridone as an active compound and pharmaceutically acceptable carriers and/or diluents are also disclosed. Finally, there is disclosed the pro-inflammatory activity of abscisic acid (ABA), a plant hormone which is also found in mammal serum and against which fluridone acts an inhibitor.
    Type: Application
    Filed: October 6, 2006
    Publication date: October 2, 2008
    Inventors: Elena Zocchi, Lucrezia Guida, Santina Bruzzone, Sonia Scarfi, Mirko Magnone, Giovanna Basile, Umberto Benatti, Antonio De Flora, Illana Moreschi, Luisa Franco, Annalisa Salis
  • Novel Adenyl Dinucleotides with Antitumour Activity and a Method of preparing Thereof
    Publication number: 20080194509
    Abstract: The invention relates to novel adenyl dinucleotides which are isomers of the dinucleotide Ap2A, having formulae (I) and (II). The dinucleotides of the invention have antitumour activity, particularly against tumours of haematological origin, such as for example leukaemias and lymphomas. The invention further relates to the use of such dinucleotides as antitumour medicaments. Finally, the invention relates to an enzymatic method for preparing the dinucleotides of formulae (I) and (II) and to an enzymatic assay method for the dinucleotide of formula (I) which is based on its complete conversion to NAD+.
    Type: Application
    Filed: April 28, 2006
    Publication date: August 14, 2008
    Applicants: UNIVERSITA' DEGLI STUDI DI GENOVA, CENTRO BIOTECNOLOGIE AVANZATE
    Inventors: Giovanna Basile, Umberto Benatti, Santina Bruzzone, Gianluca Damonte, Antonio De Flora, Ernesto Fattorusso, Luisa Franco, Lucrezia Guida, Orazio Taglialatela-Scafati, Elena Zocchi