Patents by Inventor Lucy A. WARD

Lucy A. WARD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenicity of a CpG-adjuvanted recombinant plague vaccine
    Patent number: 12364745
    Abstract: The present disclosure relates to immunogenic compositions comprising at least one Yersinia pestis (Y. pestis) antigen, an aluminum salt adjuvant, and an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against Y. pestis in a subject in need thereof. The present disclosure also relates to kits and methods using the immunogenic compositions, or two separate compositions which together comprise the antigen, the aluminum salt adjuvant, and the oligonucleotide.
    Type: Grant
    Filed: June 29, 2023
    Date of Patent: July 22, 2025
    Assignees: Dynavax Technologies Corporation, The Government of the United States, as Represented by the Secretary of the Army
    Inventors: Robert S. Janssen, David Novack, Wai Kwan Chung, Andrew M. Glenn, Lucy A. Ward
  • IMMUNOGENICITY OF A CPG-ADJUVANTED RECOMBINANT PLAGUE VACCINE
    Publication number: 20240165215
    Abstract: The present disclosure relates to immunogenic compositions comprising at least one Yersinia pestis (Y. pestis) antigen, an aluminum salt adjuvant, and an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against Y. pestis in a subject in need thereof. The present disclosure also relates to kits and methods using the immunogenic compositions, or two separate compositions which together comprise the antigen, the aluminum salt adjuvant, and the oligonucleotide.
    Type: Application
    Filed: June 29, 2023
    Publication date: May 23, 2024
    Applicants: Dynavax Technologies Corporation, The Government of the United States, as Represented by the Secretary of the Army
    Inventors: Robert S. JANSSEN, David Novack, Wai Kwan Chung, Andrew M. Glenn, Lucy A. Ward
  • Methods and compositions for inducing protective immunity against filovirus infection
    Patent number: 11918639
    Abstract: The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: March 5, 2024
    Assignees: Bavarian Nordic A/S, Janssen Vaccines & Prevention B.V., The United States of America, as represented by The Secretary, Department of Health and Human Service
    Inventors: Ariane Volkmann, Robin Steigerwald, Ulrike Dirmeier, Maria Grazia Pau, Benoit Christophe Stephan Callendret, Lucy A. Ward
  • METHODS AND COMPOSITIONS FOR INDUCING PROTECTIVE IMMUNITY AGAINST FILOVIRUS INFECTION
    Publication number: 20220088170
    Abstract: The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
    Type: Application
    Filed: October 11, 2021
    Publication date: March 24, 2022
    Inventors: Ariane VOLKMANN, Robin STEIGERWALD, Ulrike DIRMEIER, Maria Grazia PAU, Benoit Christophe Stephan CALLENDRET, Lucy A. WARD
  • Methods and compositions for inducing protective immunity against filovirus infection
    Patent number: 11173201
    Abstract: The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: November 16, 2021
    Assignees: Bavarian Nordic A/S, Janssen Vaccines & Prevention B.V., The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Ariane Volkmann, Robin Steigerwald, Ulrike Dirmeier, Maria Grazia Pau, Benoit Christophe Stephan Callendret, Lucy A. Ward
  • Methods and compositions for enhancing immune responses
    Patent number: 10561722
    Abstract: Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime and an adenovirus vector as a boost and is characterized by a high level of antibody response specific to the immunogen, and an enhanced cellular immune response. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: February 18, 2020
    Assignees: Bavarian Nordic A/S, Janssen Vaccines & Prevention B.V., The United States of America, as represented by The Secretary, Department of Health and Human Services
    Inventors: Ariane Volkmann, Robin Steigerwald, Ulrike Dirmeier, Benoit Christophe Stephan Callendret, Macaya Julie Douoguih, Lucy A. Ward
  • Methods and compositions for inducing protective immunity against filovirus infection
    Patent number: 10561721
    Abstract: The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: February 18, 2020
    Assignees: Bavarian Nordic A/S, Janssen Vaccines & Prevention B.V., The United States of America, as represented by The Secretary, Department of Health and Human Services
    Inventors: Ariane Volkmann, Robin Steigerwald, Ulrike Dirmeier, Maria Grazia Pau, Benoit Christophe Stephan Callendret, Lucy A. Ward
  • METHODS AND COMPOSITIONS FOR INDUCING PROTECTIVE IMMUNITY AGAINST FILOVIRUS INFECTION
    Publication number: 20200038500
    Abstract: The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
    Type: Application
    Filed: October 17, 2019
    Publication date: February 6, 2020
    Inventors: Ariane VOLKMANN, Robin STEIGERWALD, Ulrike DIRMEIER, Maria Grazia PAU, Benoit Christophe Stephan CALLENDRET, Lucy A. WARD
  • METHODS AND COMPOSITIONS FOR ENHANCING IMMUNE RESPONSES
    Publication number: 20170340721
    Abstract: Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime and an adenovirus vector as a boost and is characterized by a high level of antibody response specific to the immunogen, and an enhanced cellular immune response. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.
    Type: Application
    Filed: September 3, 2015
    Publication date: November 30, 2017
    Inventors: Ariane VOLKMANN, Robin STEIGERWALD, Ulrike DIRMEIER, Benoit Christophe Stephan CALLENDRET, Macaya Julie DOUOGUIH, Lucy A. WARD
  • METHODS AND COMPOSITIONS FOR INDUCING PROTECTIVE IMMUNITY AGAINST FILOVIRUS INFECTION
    Publication number: 20170290904
    Abstract: The present invention provides compositions, vaccines and methods for inducing protective immunity against filovirus infection, particularly protective immunity against infection of one or more subtypes of Ebola viruses and Marburg virus.
    Type: Application
    Filed: September 3, 2015
    Publication date: October 12, 2017
    Applicants: Bavarian Nordic A/S, Janssen Vaccines & Prevention B.V., The United States of America, as represented by the Secretary Department of Health and Human Ser..
    Inventors: Ariane VOLKMANN, Robin STEIGERWALD, Ulrike DIRMEIER, Maria Grazia PAU, Benoit Christophe CALLENDRET, Lucy A. WARD