Abstract: Embodiments described herein relate to compounds for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. Further embodiments relate to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic conversion of specific substrates which are contained in the compositions. Additional embodiments relate to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Abstract: Embodiments described herein relate to compounds for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. Further embodiments relate to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic conversion of specific substrates which are contained in the compositions. Additional embodiments relate to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Abstract: Provided herein are microbial infection indicator devices, including dressing with indicators, standalone indicator inserts or disks that can be freely placed at a wound site or dressing, and applications thereof for displaying a visible or detectable signal to a user upon detection of an analyte or biomarker indicative of an infection, such as a color change.

Abstract: A wound dressing is selectively configurable for use in a pressure gradient wound therapy system and for use without a pressure gradient wound therapy system. The wound dressing can include a covering layer, an aperture and a microbial barrier. The microbial barrier can be arranged to cover the aperture.

Abstract: A wound dressing is selectively configurable for use in a pressure gradient wound therapy system and for use without a pressure gradient wound therapy system. The wound dressing can include a covering layer, an aperture and a base plate. the base plate can be configured to sealingly receive a connector part.

Abstract: Provided herein are microbial infection indicator devices, including dressing with indicators, standalone indicator inserts or disks that can be freely placed at a wound site or dressing, and applications thereof for displaying a visible or detectable signal to a user upon detection of an analyte or biomarker indicative of an infection, such as a color change.

Abstract: Embodiments described herein relate to compounds for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. Further embodiments relate to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic conversion of specific substrates which are contained in the compositions. Additional embodiments relate to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Abstract: Polymeric superporous hydrogels, methods for making the same, and wound dressings incorporating the same are disclosed herein. The polymeric superporous hydrogels may be PVA-based hydrogel foams. The polymeric superporous hydrogels may exhibit intrinsic antimicrobial activity against Gram-positive bacteria. The polymeric superporous hydrogels may be well suited for incorporation into wound dressings or the like.

Abstract: The invention relates to a chemically modified cellulose based dressing particularly for use in the dressing of wounds but also for use as a packing material. Dressings according to the invention seek to mitigate the problems associated with shrinkage encountered with fibrous dressings made of gel-forming fibres and comprise a compressed body of chemically modified polysaccharide having a density of at least 0.08 g/cm3.

Abstract: Embodiments described herein relate to compounds for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. Further embodiments relate to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic conversion of specific substrates which are contained in the compositions. Additional embodiments relate to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Abstract: Provided herein are microbial infection indicator devices, including dressing with indicators, standalone indicator inserts or disks that can be freely placed at a wound site or dressing, and applications thereof for displaying a visible or detectable signal to a user upon detection of an analyte or biomarker indicative of an infection, such as a color change.

Abstract: Antibacterial nanofibres and methods for their preparation are described. Antibacterial nanofibres include as-spun alginate nanofibres treated with silver to generate silver-alginate nanofibres. Antibacterial nanofibres provided are useful components of wound dressings, wherein the wound dressings optionally further comprise malodor absorbing agents such as cyclodextrins.

Abstract: The invention relates to a chemically modified cellulose based dressing particularly for use in the dressing of wounds but also for use as a packing material. Dressings according to the invention seek to mitigate the problems associated with shrinkage encountered with fibrous dressings made of gel-forming fibres and comprise a compressed body of chemically modified polysaccharide having a density of at least 0.08 g/cm3.