Patents by Inventor Lucy Ellen DesJardin

Lucy Ellen DesJardin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of M. tuberculosis complex via reverse transcriptase SDA
    Patent number: 6204026
    Abstract: The present invention provides primers which can be used for M. tuberculosis complex-specific detection of &agr;-antigen DNA in a diagnostic assay performed on clinical specimens or in a culture-confirmation assay following growth of the organism in vitro. These primers and probes can also be employed in a reverse transcriptase-mediated amplification system for M. tuberculosis complex &agr;-antigen mRNA. Such an assay provides a means by which to determine the viability of M. tuberculosis complex organisms either in clinical specimens or when grown in culture. Also described are methods for the detection of the products of amplification with a radiolabeled probe by chemiluminescent assay or fluorescence polarization analysis.
    Type: Grant
    Filed: November 5, 1997
    Date of Patent: March 20, 2001
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Lucy Ellen DesJardin, Mac Donald Cave, Kathleen Davis Eisenach
  • Detection of M. tuberculosis complex via reverse transcriptase SDA
    Patent number: 6156508
    Abstract: The present invention provides primers which can be used for M. tuberculosis complex-specific detection of .alpha.-antigen DNA in a diagnostic assay performed on clinical specimens or in a culture-confirmation assay following growth of the organism in vitro. These primers and probes can also be employed in a reverse transcriptase-mediated amplification system for M. tuberculosis complex .alpha.-antigen mRNA. Such an assay provides a means by which to determine the viability of M. tuberculosis complex organisms either in clinical specimens or when grown in culture. The specific DNA or mRNA target region can be amplified using SDA, PCR, LCR, Nucleic Acid Sequence Based Amplification (NASBA), Self-sustained Sequence Replication (3SR) or Q.beta. Replicase-mediated systems. Also described are methods for the detection of the products of amplification with a radiolabeled probe by chemiluminescent assay or fluorescence polarization analysis.
    Type: Grant
    Filed: November 5, 1997
    Date of Patent: December 5, 2000
    Inventors: Patricia Anne Spears, Tobin James Hellyer, Lucy Ellen DesJardin, Mac Donald Cave, Kathleen Davis Eisenach