Patents by Inventor Lucy Liaw

Lucy Liaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies against osteopontin
    Patent number: 8399207
    Abstract: The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein. The present invention also relates to assays for the determination of the presence of osteopontin fragments in samples obtained from subjects and, further, the correlation of osteopontin fragment levels fragment levels with disease detection, progression and prognosis.
    Type: Grant
    Filed: January 3, 2011
    Date of Patent: March 19, 2013
    Assignee: Maine Medical Center
    Inventors: Lucy Liaw, Ah-Kau Ng
  • MONOCLONAL ANTIBODIES AGAINST OSTEOPONTIN
    Publication number: 20110165697
    Abstract: The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein. The present invention also relates to assays for the determination of the presence of osteopontin fragments in samples obtained from subjects and, further, the correlation of osteopontin fragment levels fragment levels with disease detection, progression and prognosis.
    Type: Application
    Filed: January 3, 2011
    Publication date: July 7, 2011
    Applicants: UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES, MAINE MEDICAL CENTER
    Inventors: Lucy Liaw, Ah-Kau Ng
  • Monoclonal antibodies against osteopontin
    Patent number: 7867725
    Abstract: The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein. The present invention also relates to assays for the determination of the presence of osteopontin fragments in samples obtained from subjects and, further, the correlation of osteopontin fragment levels fragment levels with disease detection, progression and prognosis.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: January 11, 2011
    Assignees: Maine Medical Center, University of Maine System Board
    Inventors: Lucy Liaw, Ah-Kau Ng
  • Inhibiting breast cancer cell growth by administering an intracellular domain of NOTCH2
    Patent number: 7700113
    Abstract: The present invention relates to the ability of constitutively active Notch 2 to function as an inhibitor of breast cancer. The invention provides methods and compositions for inhibiting breast cancer cells by using hNotch2ICD polypeptides.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: April 20, 2010
    Assignee: Maine Medical Research Institute, a division of Maine Medical Center
    Inventor: Lucy Liaw
  • Monoclonal antibodies against osteopontin
    Publication number: 20080176337
    Abstract: The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein. The present invention also relates to assays for the determination of the presence of osteopontin fragments in samples obtained from subjects and, further, the correlation of osteopontin fragment levels fragment levels with disease detection, progression and prognosis.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 24, 2008
    Inventors: Lucy Liaw, Ah-Kau Ng
  • Notch2 signaling as a breast cancer suppressor pathway
    Publication number: 20080112940
    Abstract: The present invention relates to the ability of constitutively active Notch 2 to function as an inhibitor of breast cancer. The invention provides methods and compositions for inhibiting breast cancer cells by using hNotch2ICD polypeptides.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 15, 2008
    Applicant: MAINE MEDICAL CENTER RESEARCH INSTITUTE
    Inventor: Lucy Liaw