Abstract: A method of regulating data flow in a wireless communication network includes: collecting data regarding dynamic loading of sector-carrier pairs (pilots) in communication sectors of the wireless communication network; obtaining data rates for data flows of the pilots to access terminals within the wireless communication network; determining one or more pilots to use for conveying data in the wireless communication network based on the data rates and the dynamic loading; and altering data flow over the pilots by at least one of changing a data rate over at least one of the pilots or changing a combination of pilots used by the wireless communication network for conveying data to increase total data flow.

Abstract: The present disclosure provides compositions and methods for modulating gene expression by using EGS to target miRNA. Another aspect of the present disclosure is the use of EGS to target mitochondrial RNA. MiRNA targets may include immature or mature forms of miRNA, such as miRNA overexpressed in diseases such as cancer.