Patents by Inventor Ludger Ickenstein

Ludger Ickenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VIRAL VECTORS AND NUCLEIC ACIDS FOR USE IN THE TREATMENT OF ILD, PF-ILD AND IPF
    Publication number: 20240011033
    Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.
    Type: Application
    Filed: November 4, 2021
    Publication date: January 11, 2024
    Inventors: Sebastian Kreuz, Ludger Ickenstein, Marc Kaestle, Stephan Klee, Holger Klein, Thorsten Lamla, Benjamin Strobel
  • VIRAL VECTORS AND NUCLEIC ACIDS FOR USE IN THE TREATMENT OF ILD, PF-ILD AND IPF
    Publication number: 20230416738
    Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF #1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF #1-induced lung fibrosis model.
    Type: Application
    Filed: November 4, 2020
    Publication date: December 28, 2023
    Inventors: Sebastian Kreuz, Holger Klein, Benjamin Strobel, Stephan Klee, Thorsten Lamla, Marc Kaestle, Ludger Ickenstein
  • VIRAL VECTORS AND NUCLEIC ACIDS FOR USE IN THE TREATMENT OF ILD, PF-ILD AND IPF
    Publication number: 20230407303
    Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.
    Type: Application
    Filed: November 4, 2021
    Publication date: December 21, 2023
    Inventors: Sebastian Kreuz, Holger Klein, Benjamin Strobel, Stephan Klee, Thorsten Lamla, Marc Kaestle, Ludger Ickenstein
  • Lipids and compositions for intracellular delivery of biologically active compounds
    Patent number: 9636302
    Abstract: The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: May 2, 2017
    Assignee: AXOLABS GMBH
    Inventors: Rainer Constien, Anke Geick, Philipp Hadwiger, Torsten Haneke, Ludger Ickenstein, Carla Alexandra Hernandez Prata, Andrea Schuster, Timo Weide
  • NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20160324781
    Abstract: The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
    Type: Application
    Filed: July 26, 2016
    Publication date: November 10, 2016
    Inventors: Rainer CONSTIEN, Anke GEICK, Philipp HADWIGER, Torsten HANEKE, Ludger ICKENSTEIN, Carla Alexandra HERNANDEZ PRATA, Andrea SCHUSTER, Timo WEIDE
  • Lipid carrier compositions with enhanced blood stability
    Publication number: 20050118250
    Abstract: Liposomes that contain at least 10 mol % of a negatively charged lipid coupled to an non-zwitterionic moiety are stable in the blood. Liposomes containing at least 1 mol % of such lipids may be frozen safely.
    Type: Application
    Filed: November 13, 2002
    Publication date: June 2, 2005
    Inventors: Paul Tardi, Murray Webb, Lawrence Mayer, Ludger Ickenstein