Patents by Inventor Ludivine MOINE

Ludivine MOINE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
    Publication number: 20240116905
    Abstract: Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
    Type: Application
    Filed: April 28, 2023
    Publication date: April 11, 2024
    Inventors: Alexandre Côté, Victor S. Gehling, Avinash Khanna, Ludivine Moine, Jacob I. Stuckey
  • Modulators of methyl modifying enzymes, compositions and uses thereof
    Patent number: 11919912
    Abstract: Provided are novel compounds of Formula (I): Formula (I); and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: March 5, 2024
    Assignee: Constellation Pharmaceuticals, Inc.
    Inventors: Alexandre Côté, Avinash Khanna, Ludivine Moine
  • Heteroaryl sulfone-based conjugation handles, methods for their preparation, and their use in synthesizing antibody drug conjugates
    Patent number: 11712480
    Abstract: The present invention is directed to novel heteroaryl sulfone-based conjugation handles of the formula: (wherein R1, R2, Het, D, E, X, Y, Z, m, n, p, q, r, s and t are as defined herein), methods for their preparation, their use in synthesizing antibody drug conjugates, and the resulting antibody drug conjugates made with components having heteroaryl sulfone-based conjugation handles.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: August 1, 2023
    Assignee: Pfizer Inc.
    Inventors: Russell George Dushin, Daniel P. Uccello, Jeremy Starr, Ye Che, Mark Flanagan, Jeffrey M. Casavant, Christopher John O'Donnell, Gary Frederick Filzen, Jennifer Young, Joseph A. Abramite, Lawrence N. Tumey, Ludivine Moine, Adam Matthew Gilbert, Lee R. Roberts
  • Modulators of methyl modifying enzymes, compositions and uses thereof
    Patent number: 11459315
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compostions thereof, which are useful for treating a variety of conditions associated with methyl modifying enzymes.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: October 4, 2022
    Assignee: Constellation Pharmaceuticals, Inc.
    Inventors: Jehrod B. Brenneman, Alexandre Côté, Victor S. Gehling, Avinash Khanna, Julian R. Levell, Ludivine Moine
  • Modulators of methyl modifying enzymes, compositions and uses thereof
    Patent number: 11274095
    Abstract: Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: March 15, 2022
    Assignee: Constellation Pharmaceuticals, Inc.
    Inventors: Alexandre Côté, Victor S. Gehling, Avinash Khanna, Ludivine Moine, Jacob I. Stuckey
  • HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES
    Publication number: 20210308276
    Abstract: The present invention is directed to novel heteroaryl sulfone-based conjugation handles of the formula: (wherein R1, R2, Het, D, E, X, Y, Z, m, n, p, q, r, s and t are as defined herein), methods for their preparation, their use in synthesizing antibody drig conjugates, and the resulting antibody drig conjugates made with components having heteroaryl sulfone-based conjugation handles.
    Type: Application
    Filed: July 31, 2017
    Publication date: October 7, 2021
    Applicant: PFIZER INC.
    Inventors: Russell George DUSHIN, Daniel P. UCCELLO, Jeremy STARR, Ye CHE, Mark FLANAGAN, Jeffrey M. CASAVANT, Christopher John O'DONNELL, Gary Frederick FILZEN, Jennifer YOUNG, Joseph A. ABRAMITE, Lawrence N. TUMEY, Ludivine MOINE, Adam Matthew GILBERT, Lee R. ROBERTS
  • MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
    Publication number: 20210230148
    Abstract: Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compostions thereof, which are useful for treating a variety of conditions associated with methyl modifying enzymes.
    Type: Application
    Filed: November 8, 2018
    Publication date: July 29, 2021
    Inventors: Jehrod B. Brenneman, Alexandre Côté, Victor S. Gehling, Avinash Khanna, Julian R. Levell, Ludivine Moine
  • STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES
    Publication number: 20210205463
    Abstract: The present invention provides stability-modulated antibody-drug conjugates, stability-modulating linker components used to make these stability-modulated antibody-drug conjugates, therapeutic methods using stability-modulated antibody-drug conjugates, and methods of making stability modulating linkers and stability-modulated antibody-drug conjugates.
    Type: Application
    Filed: February 23, 2021
    Publication date: July 8, 2021
    Applicants: PFIZER INC., RINAT NEUROSCIENCE CORP.
    Inventors: Russell George DUSHIN, Pavel STROP, Magdalena Grazyna DORYWALSKA, Ludivine MOINE
  • MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
    Publication number: 20210206776
    Abstract: Provided are novel compounds of Formula (I): Formula (I); and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
    Type: Application
    Filed: May 17, 2019
    Publication date: July 8, 2021
    Inventors: Alexandre Côté, Avinash Khanna, Ludivine Moine
  • Stability-modulating linkers for use with antibody drug conjugates
    Patent number: 10967068
    Abstract: The present invention provides stability-modulated antibody-drug conjugates, stability-modulating linker components used to make these stability-modulated antibody-drug conjugates, therapeutic methods using stability-modulated antibody-drug conjugates, and methods of making stability modulating linkers and stability-modulated antibody-drug conjugates.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: April 6, 2021
    Assignees: PFIZER INC., RINAT NEUROSCIENCE CORP.
    Inventors: Russell George Dushin, Pavel Strop, Magdalena Grazyna Dorywalska, Ludivine Moine
  • MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
    Publication number: 20200317651
    Abstract: Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
    Type: Application
    Filed: April 23, 2020
    Publication date: October 8, 2020
    Inventors: Alexandre Côté, Victor S. Gehling, Avinash Khanna, Ludivine Moine, Jacob I. Stuckey
  • Modulators of methyl modifying enzymes, compositions and uses thereof
    Patent number: 10689371
    Abstract: Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: June 23, 2020
    Assignee: Constellation Pharmaceuticals, Inc.
    Inventors: Alexandre Côté, Victor S. Gehling, Avinash Khanna, Ludivine Moine, Jacob I. Stuckey
  • MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
    Publication number: 20190322651
    Abstract: Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
    Type: Application
    Filed: April 18, 2019
    Publication date: October 24, 2019
    Inventors: Alexandre Côté, Victor S. Gehling, Avinash Khanna, Ludivine Moine, Jacob I. Stuckey
  • STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES
    Publication number: 20180140714
    Abstract: The present invention provides stability-modulated antibody-drug conjugates, stability-modulating linker components used to make these stability-modulated antibody-drug conjugates, therapeutic methods using stability-modulated antibody-drug conjugates, and methods of making stability modulating linkers and stability-modulated antibody-drug conjugates.
    Type: Application
    Filed: August 14, 2015
    Publication date: May 24, 2018
    Applicants: PFIZER INC., RINAT NEUROSCIENCE CORP.
    Inventors: Russell George DUSHIN, Pavel STROP, Magdalena Grazyna DORYWALSKA, Ludivine MOINE