Patents by Inventor Ludmila Iourtchenko

Ludmila Iourtchenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compositions and methods for treating diseases that involve angiogenesis
    Publication number: 20050277575
    Abstract: According to the present invention, S100A4 protein also known as Mts-1 interferes with the function of Annexin 2 and Annexin2/P11 tetramer by binding to Annexin 2. The present inventors have demonstrated that binding of S100A4 with Annaxin 2 modulates angiogenesis by interfering with Annexin 2 mediated tissue plasminogen activator (tPA) dependant conversion of plaminogen into plasmin and further conversion of plasmin into angiostatins. The present invention has further identified that the S100A4 protein binds to the N-terminal region of Annexin 2.
    Type: Application
    Filed: March 24, 2005
    Publication date: December 15, 2005
    Inventors: Alexandre Semov, Anatoli Onichtchenko, Ludmila Iourtchenko, Benoit Ochietti, Grzegorz Pietrzynski, Valery Alakhov