Patents by Inventor Ludmila Rizhsky

Ludmila Rizhsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and methods for production of bi-functional fatty acids in recombinant bacteria
    Patent number: 10184140
    Abstract: A method of producing bi-functional fatty acids comprising introducing into a host cell or organism, which comprises one or more ?- or ?-1 functionalized acyl-CoAs, and expressing therein a KASIII, which can use one or more of the ?- or ?-1 functionalized acyl-CoAs as a substrate; a method of producing a ?-1 hydroxy branched fatty acid, a ?-1 branched fatty acid, or a combination thereof by culturing a mutant E. coli, which does not express a functional KASIII from the endogenous fabH gene and expresses a phaA and a phaB and a functional exogenous KASIII; and a mutant E. coli, a method of making the mutant, a culture comprising the mutant, and a composition comprising ?-1 hydroxy branched fatty acids, a ?-1 branched fatty acids, or a combination thereof obtained from the culture.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: January 22, 2019
    Assignees: Iowa State University Research Foundation, Inc., OmegaChea
    Inventors: Shivani Garg, Xiaochen Yu, Huanan Jin, Marna Yandeau-Nelson, Basil Nikolau, Ludmila Rizhsky
  • MATERIALS AND METHODS FOR PRODUCTION OF BI-FUNCTIONAL FATTY ACIDS IN RECOMBINANT BACTERIA
    Publication number: 20160168603
    Abstract: A method of producing bi-functional fatty acids comprising introducing into a host cell or organism, which comprises one or more ?- or ?-1 functionalized acyl-CoAs, and expressing therein a KASIII, which can use one or more of the ?- or ?-1 functionalized acyl-CoAs as a substrate; a method of producing a ?-1 hydroxy branched fatty acid, a ?-1 branched fatty acid, or a combination thereof by culturing a mutant E. coli, which does not express a functional KASIII from the endogenous fabH gene and expresses a phaA and a phaB and a functional exogenous KASIII; and a mutant E. coli, a method of making the mutant, a culture comprising the mutant, and a composition comprising ?-1 hydroxy branched fatty acids, a ?-1 branched fatty acids, or a combination thereof obtained from the culture.
    Type: Application
    Filed: November 30, 2015
    Publication date: June 16, 2016
    Inventors: Shivani Garg, Xiaochen Yu, Huanan Jin, Marna Yandeau-Nelson, Basil Nikolau, Ludmila Rizhsky