Patents by Inventor Ludovic HALBY

Ludovic HALBY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hemi-synthetic trilobine analogs for use as a drug
    Patent number: 10544156
    Abstract: The invention concerns a compound of the following formula (I) or a pharmaceutically acceptable salt or solvate thereof as well as a pharmaceutical composition containing such a compound, and the use of such a compound as a drug, notably as a DNMT inhibitor, in particular in the treatment of cancer.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: January 28, 2020
    Assignees: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Ludovic Halby, Yoann Menon, El Bachir Kaloun, Christophe Long, Paola B. Arimondo
  • Substituted quinazoline derivatives as DNA methyltransferase inhibitors
    Patent number: 10450299
    Abstract: The present invention relates to compounds of the following formula (I) and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: October 22, 2019
    Assignees: Centre National de la Recherche Scientifique (CNRS), Pierre Fabre Medicament, Sapienza Universita di Roma
    Inventors: Ludovic Halby, Paola Arimondo, Antonello Mai, Dante Rotili
  • HEMI-SYNTHETIC TRILOBINE ANALOGS FOR USE AS A DRUG
    Publication number: 20190062339
    Abstract: The invention concerns a compound of the following formula (I) or a pharmaceutically acceptable salt or solvate thereof as well as a pharmaceutical composition containing such a compound, and the use of such a compound as a drug, notably as a DNMT inhibitor, in particular in the treatment of cancer.
    Type: Application
    Filed: October 3, 2016
    Publication date: February 28, 2019
    Applicants: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Ludovic HALBY, Yoann MENON, El Bachir KALOUN, Christophe LONG, Paola B. ARIMONDO
  • Substituted Quinazoline Derivatives as DNA Methyltransferase Inhibitors
    Publication number: 20180118717
    Abstract: The present invention relates to compounds of the following formula (I) and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: March 25, 2016
    Publication date: May 3, 2018
    Inventors: Ludovic Halby, Paola Arimondo, Antonello Mai, Dante Rotili
  • Quinazoline derivatives and their use as DNA methyltransferase inhibitors
    Patent number: 9951044
    Abstract: The present invention relates to compounds of the following formula (I): and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: April 24, 2018
    Assignees: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Ludovic Halby, Paola Barbara Arimondo
  • QUINAZOLINE DERIVATIVES AND THEIR USE AS DNA METHYLTRANSFERASE INHIBITORS
    Publication number: 20160229834
    Abstract: The present invention relates to compounds of the following formula (I): and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: September 19, 2014
    Publication date: August 11, 2016
    Applicants: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Ludovic HALBY, Paola Barbara ARIMONDO