Patents by Inventor Ludovic PEAUGER

Ludovic PEAUGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9376387
    Abstract: A compound of formula (I) in which the dotted lines indicate the presence of at least one double bond; n=0 to 4; R3 and R4 are H, or when n=1, R3 and R4 can also form together a double bond between the carbon atoms, and m=0, 1 or 2, Z is CH or N or Z is C and —CHR3— is ?CH— linked by the double bond to cyclopentanone; or ?(?)m- is absent, and Z is NH, >N-alkyl, >N-phenyl, >N-benzyl or >N heteroaryl; R8 is alkyl, aryl or heteroaryl which can be optionally substituted; EWG represents an electron withdrawing group selected from the group comprising COOR, COSR, CONRR?, CN, COR, CF3, SOR, SO2R, SONRR?, SO2NRR?, NO2, halogen, heteroaryl; and the pharmaceutical salts and stereisomers thereof. The compounds of formula (I) are potent in the treatment of neurodegenerative diseases such as Alzheimer's disease.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: June 28, 2016
    Inventors: Francis Marsais, Vincent Levacher, Cyril Papamicael, Pierre Bohn, Ludovic Peauger, Vincent Gembus, Nicolas Le Fur, Marie-Laurence Dumartin-Lepine
  • Publication number: 20150353493
    Abstract: A compound of formula (I) in which the dotted lines indicate the presence of at least one double bond; n=0 to 4; R3 and R4 are H, or when n=1, R3 and R4 can also form together a double bond between the carbon atoms, and m=0, 1 or 2, Z is CH or N or Z is C and —CHR3— is ?CH— linked by the double bond to cyclopentanone; or ?(?)m- is absent, and Z is NH, >N-alkyl, >N-phenyl, >N-benzyl or >N heteroaryl; R8 is alkyl, aryl or heteroaryl which can be optionally substituted; EWG represents an electron withdrawing group selected from the group comprising COOR, COSR, CONRR?, CN, COR, CF3, SOR, SO2R, SONRR?, SO2NRR?, NO2, halogen, heteroaryl; and the pharmaceutical salts and stereisomers thereof. The compounds of formula (I) are potent in the treatment of neurodegenerative diseases such as Alzheimer's disease.
    Type: Application
    Filed: January 24, 2014
    Publication date: December 10, 2015
    Applicants: INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE ROUEN, VFP THERAPIES
    Inventors: Francis MARSAIS, Vincent LEVACHER, Cyril PAPAMICAEL, Pierre BOHN, Ludovic PEAUGER, Vincent GEMBUS, Nicolas LE FUR, Marie-Laurence DUMARTIN-LEPINE