Abstract: New physiologically active 1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones having the general formula ##STR1## wherein R.sub.1 is hydrogen or phenyl, R.sub.2 is hydrogen, alkyl, C.sub.3 -C.sub.6 -alkenyl, C.sub.1 -C.sub.4 -acyl, hydroxyalkyl, alkoxyalkyl, mono- or dialkylaminoalkyl, cyanoalkyl, alkoxyacetyl, carbamoylalkyl, acetamido-C.sub.2 -C.sub.5 -alkyl, alkoxycarbonylalkyl or (tetrahydro-2H-pyran-2-yloxy)alkyl, the alkyl and the alkoxy radicals having 1 to 5 carbon atoms, R.sub.4 is hydrogen or C.sub.1 -C.sub.4 -alkyl, R.sub.5 is hydrogen, C.sub.1 -C.sub.4 -alkyl or phenyl, R.sub.7 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkoxy and R.sub.8 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkyl, at least one of the symbols R.sub.1 to R.sub.8 being other hydrogen, processes for the preparation thereof and pharmaceutical compositions containing the same. In particular, the compounds of this invention are useful in the treatment of memory disorders.