Patents by Inventor Ludwig Bar

Ludwig Bar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8641974
    Abstract: A device dynamically detects particles of a fluid. The device can be miniaturized for detecting and selecting magnetized particles, particularly cells.
    Type: Grant
    Filed: November 27, 2008
    Date of Patent: February 4, 2014
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ludwig Bär, Oliver Hayden
  • Publication number: 20130004982
    Abstract: A magnetic flow cytometry apparatus for detection of cells labeled with magnetic nanoparticles has at least one pair of oppositely oriented magnets to provide between the magnets a first magnetic field region with a low magnetic field strength and to provide at poles of the magnets second magnetic field regions with a high magnetic field strength. The magnetic labeled cells provided within a flow input into the magnetic flow cytometry apparatus are enriched in at least one of the second magnetic field regions and supplied to the first magnetic field region, where a magnetic field is applied to the enriched magnetic labeled cells to measure the magnetic relaxation of the magnetic labeled cells in response to the applied magnetic field.
    Type: Application
    Filed: June 29, 2011
    Publication date: January 3, 2013
    Applicants: The Regents of the University of California, Siemens Aktiengesellschaft
    Inventors: Ludwig Bär, Oliver Hayden, Michael Johannes Helou, Mischa Megens, Mathias Reisbeck, Manfred Rührig, Sandro Francesco Tedde
  • Patent number: 8263331
    Abstract: A device and a method are disclosed for the detection and/or for the quantification of an analyte. In at least one embodiment, the device includes a basic matrix and magnetized nanoparticles, which are arranged in moveable fashion in or at the basic matrix and to which catcher molecules that bind specifically to the analyte are anchored. Further, the mobility of the nanoparticle in the basic matrix can be influenced by a binding of the analyte to be detected to the catcher molecules and can be read out magnetically.
    Type: Grant
    Filed: January 22, 2007
    Date of Patent: September 11, 2012
    Assignee: Siemens Aktiengesellschaft
    Inventors: Joachim Bangert, Ludwig Bär, Thomas Ehben, Hans-Dieter Feucht, Christian Zilch
  • Publication number: 20120187938
    Abstract: A flow cytometer has a flow chamber in which labeled cells are highly likely to be detected by a corresponding sensor as a medium carrying the magnetically labeled cells flows through the flow chamber. The flow chamber has at least one sensor positioned on an inner surface thereof to detect the cells. The flow chamber also has a magnetic or magnetizable cell guiding device which can be positioned upstream of the sensor in the direction of flow to guide the flowing, magnetically labeled cells directly across the sensor, so that only a small percentage of labeled cells pass outside of the reach of the sensor.
    Type: Application
    Filed: August 17, 2010
    Publication date: July 26, 2012
    Applicant: Siemens Aktiengesellschaft
    Inventors: Ludwig Bär, Helmut Eckert, Oliver Hayden, Sandro Francesco Tedde, Michael Vieth, Roland Weiss
  • Publication number: 20120182007
    Abstract: Magnetically labeled cells in a flow chamber cytometer are detected by a GMR sensor. The flow chamber includes a cell guiding device having at least one first and one second magnetic or magnetizable flow strip. The flow strips, which serve to guide the flowing cells across the sensor in a target-oriented manner, are mounted at a distance from each other such that a magnetic field BF is produced between them. The GMR sensor is arranged in the region of the magnetic field BF between the flow strips such that the magnetic field BF can be used as the operating magnetic field BGMR of the GMR sensor. In this way, the need for additional magnets for operating the GMR sensor is eliminated.
    Type: Application
    Filed: August 17, 2010
    Publication date: July 19, 2012
    Inventors: Ludwig Bär, Helmut Eckert, Oliver Hayden, Sandro Francesco Tedde, Michael Vieth, Roland Weiss
  • Publication number: 20100273184
    Abstract: A device dynamically detects particles of a fluid. The device can be miniaturized for detecting and selecting magnetized particles, particularly cells.
    Type: Application
    Filed: November 27, 2008
    Publication date: October 28, 2010
    Inventors: Ludwig Bär, Oliver Hayden
  • Patent number: 7688067
    Abstract: The invention relates to a probe for electrical measurements and use of a flexible probe to produce an inflexible probe. Conventional probes comprise a substrate which is mechanically rigid. As a result only planar surfaces may be examined with the probe. According to the invention, a probe is flexibly embodied by means of a flexible substrate such that the probe may be adjusted to match various curvature radii of test bodies.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: March 30, 2010
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ludwig Bär, Werner Heinrich
  • Patent number: 7463039
    Abstract: When using a rigid substrate eddy current probe to measure a non-planer test piece, the probe must be adapted to the test piece shape in order to avoid incorrect measurement values. Disclosed is a probe which is configured in a flexible manner via a flexible substrate so as to be adjustable to different radii of curvature of a test piece. Furthermore the probe lining is also embodied in an elastic manner.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: December 9, 2008
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ludwig Bär, Werner Heinrich
  • Publication number: 20070190640
    Abstract: A device and a method are disclosed for the detection and/or for the quantification of an analyte. In at least one embodiment, the device includes a basic matrix and magnetized nanoparticles, which are arranged in moveable fashion in or at the basic matrix and to which catcher molecules that bind specifically to the analyte are anchored. Further, the mobility of the nanoparticle in the basic matrix can be influenced by a binding of the analyte to be detected to the catcher molecules and can be read out magnetically.
    Type: Application
    Filed: January 22, 2007
    Publication date: August 16, 2007
    Inventors: Joachim Bangert, Ludwig Bar, Thomas Ehben, Hans-Dieter Feucht, Christian Zilch
  • Publication number: 20070182422
    Abstract: Disclosed is a probe which is configured in a flexible manner by means of a flexible substrate so as to be adjustable to different radii of curvature of a test piece. The lining is also embodied in an elastic manner.
    Type: Application
    Filed: June 23, 2004
    Publication date: August 9, 2007
    Inventors: Ludwig Bar, Werner Heinrich
  • Publication number: 20050140366
    Abstract: The invention relates to a probe for electrical measurements and use of a flexible probe to produce an inflexible probe. Conventional probes comprise a substrate which is mechanically rigid. As a result only planar surfaces may be examined with the probe. According to the invention, a probe is flexibly embodied by means of a flexible substrate such that the probe may be adjusted to match various curvature radii of test bodies.
    Type: Application
    Filed: December 23, 2002
    Publication date: June 30, 2005
    Inventors: Ludwig Bar, Werner Heinrich
  • Patent number: 6452384
    Abstract: A scanning head for eddy-current testing includes a probe coil configuration disposed on a film on a film base. The film base is matched to a shape of an object to be tested. This allows quick, low-interference eddy-current testing. A method for producing a scanning head for an eddy-current test and an eddy-current test method are also provided.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: September 17, 2002
    Assignee: Siemens Aktiengesellschaft
    Inventors: Erich Becker, Hans-Peter Lohmann, Gabriel Daalmans, Klaus Ludwig, Ludwig Bär