Abstract: The dosing apparatus comprises a conveying device (5), which is driven by at least one conveying drive (4), for conveying fluid from the interior (3) of a container (2). The fluid by means of the conveying device (5) is conveyable from the container to a dispensing opening (6). The conveying device (5) comprises a cylinder (7) having at least one intake opening (11) and at least one outlet opening (12) on an inner cylinder wall (8), and a first piston (9) and a second piston (10). The first piston (9) and the second piston (10) are mounted within the cylinder (7) so as to be displaceable in the longitudinal direction. Furthermore, the first piston (9) and the second piston (10) between the end sides thereof and together with a portion of the inner cylinder wall (8) delimit a variable fluid volume (17).

Abstract: The device (1) has a housing (2), and a flexible bag arranged in the housing and intended to receive a liquid. A dispensing device, in particular an injection syringe (5), is also arranged in the housing, so that it is removable from the housing. A transfer channel (6) serves for direct or indirect transfer of the liquid from the bag into the dispensing device. At least one pressure plate (7) is also provided, which can be pressed against the bag in order to empty the bag. The pressure plate is preferably activated via a spring mechanism (16), which serves as energy accumulator. The device, according to the invention, makes it possible, with a few manoeuvres, to prepare an injection liquid and deliver it to the injection syringe, with the substances being brought together by a largely automated procedure.

Abstract: A device (1) for dispensing a fluid, in particular to a patient, comprising a container (15), in particular an at least partly collapsible container, with an interior (17) for receiving the fluid. The container (15) comprises a closure piece (20) which is rigidly arranged in the container (15) in particular and on which a dispensing opening (24) is formed, wherein the fluid can be dispensed out of the interior (17) through the dispensing opening. The device (1) comprises a pump device (40) driven by a pump drive (50) in order to pump the fluid out of the interior (17) of the container (15). The pump device (40) is fluidically arranged between the interior (17) and the dispensing opening (24) so that the fluid can be pumped out of the interior (17) to the dispensing opening (24) by the pump device (40).

Abstract: The present invention relates to a dialysis machine for the purification of blood, a manifold for the dialysis machine as well as to a process for the regeneration of the dialysis bath. It is an object of the present invention to provide a dialysis machine, a manifold for the dialysis machine as well a process which facilitates the administration of medical preparations during a dialysis procedure. In order to solve the object, a dialysis machine according to the present invention comprises tubes (1, 5, 8) connected with a dialyzer (6), means for delivering pharmaceuticals into the tubes and a pump (11) for the transport of blood through the tubes and the dialyzer. The dialysis machine comprises means for administration (4) of at least one pharmaceutical by a suction effect of the pump or by a pressure effect of the pump or by an excess pressure of a gas or a liquid.

Abstract: A dispensing device (1) for dispensing a fluid comprising a base (2) having a longitudinal axis (A), a receiving chamber (14) formed in the base for the fluid, and a dispensing opening (18) formed in the base for dispensing the fluid from the receiving chamber. The dispensing opening (18) is formed in a dispensing area (4) of the dispensing device (1). Furthermore, the dispensing device (1) comprises a closure element which is movably arranged on the base. The closure element (30) comprises a dispensing channel (40) that is open to the outside. The closure element (30) is movable from a closed position, in which a fluid connection between the dispensing opening (18) and the dispensing channel (40) is interrupted, into a dispensing position, in which there is a fluid-tight fluid connection between the dispensing opening (18) and the dispensing channel (40). The dispensing device (1) includes a protective device (70).

Abstract: A device is placed upon a container that is sealed by a sealing element and filled with a liquid, the device allowing the liquid to be withdrawn. The device is provided with a penetration element with a hollow needle that is held in an unused position on a head section. The penetration element is held by guide elements on the head section so that the element can be pressed against the sealing element in a withdrawal position, in which the hollow needle penetrates the sealing element. At least one aeration channel is provided to equalize the pressure in the container during the withdrawal of the liquid, the channel running preferably along the hollow needle. The air sucked from the atmosphere enters the aeration channel via a filter. This prevents the contamination of the liquid and the latter can be withdrawn without the risk of a reverse flow.

Abstract: The invention relates to an adapter (1) for a transfer device (20) for a fluid, for the connection of a container (17) containing the fluid, wherein the container (17) is closed by a pierceable closure element (18), and the adapter (1) has an attachment (4) which can be fitted sealingly, in an attachment direction, onto a container mouth closed by the closure element. A penetration element (6) is mounted on the attachment (4) in such a way that the penetration element (6) is movable, with the aid of guide means, between a rest position (R) and a withdrawal position (E), wherein the penetration element (6) has a hollow needle (9) with which the closure element (18) can be pierced in the withdrawal position (E).

Abstract: The invention relates to a tip cap assembly for closing a distal opening of a receptacle like a syringe body or a tube in a sealed manner, and to a method for producing the tip cap. A cap assembly according to the invention comprises a frangible tip of a receptacle, preferably a pre-filled receptacle. An upper portion of the tip closes the receptacle respectively a lower tip portion comprising a passage as known from the state of the art. Hence, the receptacle is reliably sealed to prevent contamination or loss of the medication. Compared with the state of the art, a receptacle has a more effectively sealed tip. It is necessary to break the upper tip portion away in order to open the receptacle. A cap element protects the tip on one side. On the other side, unscrewing the cap breaks the upper portion away without hurting a person.

Abstract: The invention relates to a device (1) for receiving or dispensing a fluid (39), preferably containing a pharmaceutical, comprising a container that can be collapsed at least in some regions and a closure piece (2). The closure piece (2) comprises a dispensing channel (18) that fluidically connects a dispensing opening (2.1) to a removal opening (21), wherein a dispensing section (18.1) of the dispensing channel (18) communicates with the dispensing opening (2.1) and a removal section (18.2) of the dispensing channel (18) communicates with the removal opening (21). The dispensing channel (18) comprises a valve device (23) having two valve openings (22, 25), which are arranged next to one another on a valve surface (6.1). A first valve opening (25) of said valve device communicates with the dispensing opening (2.1) via the dispensing section (18.1) of the dispensing channel (18) and a second valve opening (22) communicates with the removal opening (21) via the removal section (18.

Abstract: A method and a receptacle for storing and supplying a liquid, especially a liquid medical preparation. It is an object of the invention to provide a suitable receptacle and method for storing and supplying a desired liquid quantity. It is solved by a liquid tight and preferably gas-tight receptacle, comprising a compressible tube (7) or foil bag. A rigid opening portion (6) is sealingly mounted to one end of the tube (7). The diameter of the opening portion (6) is the same as the diameter of the tube (7). The tube (7) diameter is not more than 10 mm The liquid has a volume of not more than 1.5 ml, preferably of not more than 1.3 ml. The tube (7) contains additionally a gas having a volume of 10 to 15% of the liquid volume. The tube (7) or foil bag comprises a flat portion having an inscription.

Abstract: A device is placed upon a container that is sealed by a sealing element and filled with a liquid, the device allowing the liquid to be withdrawn. The device is provided with a penetration element with a hollow needle that is held in an unused position on a head section. The penetration element is held by guide elements on the head section so that the element can be pressed against the sealing element in a withdrawal position, in which the hollow needle penetrates the sealing element. At least one aeration channel is provided to equalize the pressure in the container during the withdrawal of the liquid, the channel running preferably along the hollow needle. The air sucked from the atmosphere enters the aeration channel via a filter. This prevents the contamination of the liquid and the latter can be withdrawn without the risk of a reverse flow.

Abstract: The present invention relates to a dialysis machine for the purification of blood, a manifold for the dialysis machine as well as to a process for the regeneration of the dialysis bath. It is an object of the present invention to provide a dialysis machine, a manifold for the dialysis machine as well a process which facilitates the administration of medical preparations during a dialysis procedure. In order to solve the object, a dialysis machine according to the present invention comprises tubes (1, 5, 8) connected with a dialyzer (6), means for delivering pharmaceuticals into the tubes and a pump (11) for the transport of blood through the tubes and the dialyzer. The dialysis machine comprises means for administration (4) of at least one pharmaceutical by a suction effect of the pump or by a pressure effect of the pump or by an excess pressure of a gas or a liquid.

Abstract: The invention relates to a tip cap assembly for closing a distal opening of a receptacle like a syringe body or a tube in a sealed manner, and to a method for producing the tip cap. A cap assembly according to the invention comprises a frangible tip of a receptacle, preferably a pre-filled receptacle. An upper portion of the tip closes the receptacle respectively a lower tip portion comprising a passage as known from the state of the art. Hence, the receptacle is reliably sealed to prevent contamination or loss of the medication. Compared with the state of the art, a receptacle has a more effectively sealed tip. It is necessary to break the upper tip portion away in order to open the receptacle. A cap element protects the tip on one side. On the other side, unscrewing the cap breaks the upper portion away without hurting a person.

Abstract: The invention relates to a method for storing and supplying a liquid, especially a liquid medical preparation. The invention further relates to a receptacle for storing and supplying a liquid, especially a liquid medical preparation. It is an object of the invention to provide a suitable receptacle and method for storing and supplying a desired liquid quantity. The object of the invention is solved by a receptacle for storing and supplying a liquid which receptacle is liquid tight and preferably gas-tight comprising a tube or a foil bag which can be compressed. The tube or foil bag preferably comprises a rigid opening portion sealingly mounted to one end of the tube. The diameter of the opening portion preferably is the same as the diameter of the tube. The rigid opening portion is stable in respect of shape. The tube diameter preferably is not more than 10 mm and, in an embodiment of the invention, the tube contains a liquid, preferably a liquid medical preparation.

Abstract: Pharmaceutical compositions for oral administration, in particular administration as an oral delivery system to be swallowed directly or capable of disintegration in the oral cavity, comprising iron oxy-hydroxide in high loading.