Abstract: Derivatives of 5-aminomethyl-2-furanomethanol represented by formula (I), or pharmaceutically acceptable salts thereof, which possess calcium-antagonistic activity and are effective in lowering blood pressure, and a process for preparing and using the same: ##STR1## wherein R, R.sub.1, R.sub.2 and R.sub.2 ' each represent a lower alkyl group containing 1 to 4 carbon atoms, with the proviso that R.sub.2 and R.sub.2 ', together with N, may form a 5- or 6-membered saturated heterocyclic ring which may contain an additional heteroatom, selected from the group consisting of as O, N and S, or R.sub.2 ' represents an aralkyl group;wherein R.sub.3 and R.sub.4 are each selected from the group consisting of a hydrogen atom, a halogen, a nitro group and a methoxy group; andwherein R.sub.5 is selected from the group consisting of a halogen, a difluoromethoxy group, a trifluoromethyl group, a nitro group, a carbamylmethoxy group, a cyanomethoxy group and a mesyloxy group.

Abstract: An orally administrable and stable solution containing as an active ingredient Methoxasalen (8-methoxyfuro-[3',-2':6,7]-coumarin) of the formula ##STR1## useful in the photochemotherapy of psoriasis, to a process for the preparation thereof and to a process for the use thereof.

Abstract: Quinazoline compounds of the general formula (I): ##STR1## in which (a) R is a hydrogen atom and R.sub.1 is an -(2-pyrrolidinon-1-yl)-alkyl group,(b) R is a methyl group and R.sub.1 is an -(mono- or dialkoxyphenyl)-alkyl group, p0 (c) R together with R.sub.1 forms a piperidine ring substituted with 2-keto-1-benzimidazolinyl radical in the 4-position of the piperidine group ring; or(d) R together with R.sub.1 forms a piperazine ring substituted with a hydroxyacyl group in the 4-position of the piperazine ring.

Abstract: The disclosure is directed to new 3-hydroxy-1,4-benzodiazepine-2-ones and to the process for the preparation thereof. The compounds of the invention have the structural formula ##STR1## in which R is methoxy or nitrile, R.sub.1 is hydrogen, halogen, trifluoromethyl or nitro and R.sub.2 is hydrogen or halogen, with the proviso that R is different from methoxy, if R.sub.2 is o-halogen. The compounds have marked sedative and sleep prolonging activity when evaluated in standard pharmacological procedures.

Abstract: Novel 3-Di-n-Propyl-Acetoxy-Benzodiazepine-2-Ones and use thereof as anti-convulsant compounds.

Abstract: 2-AMINOMETHYL-4,6-DIHALOGENPHENOL DERIVATIVES AND SALTS THEREOF WITH PHYSIOLOGICALLY ACCEPTABLE ACIDS OR BASES HAVING THE FORMULA: ##STR1## wherein X is the same halogen in both positions, R.sub.1 is a hydrogen atom or a lower alkyl group, R.sub.2 is an alkyl, cycloalkyl, aryl or aralkyl group, or R.sub.1 and R.sub.2 together with the nitrogen atom may form a saturated heterocyclic ring, which ring may be interrupted by an oxygen, nitrogen or sulfur atom, R.sub.3 is a hydrogen atom, an alkyl, alkoxyalkyl, carboxyalkyl, carbamylalkyl, aralkyl, acyl or sulfonyl group or a base radical, e.g. an alkali metal atom, and R.sub.3 " is a cyanoalkyl, hydroxyalkyl, carbalkoxy-alkyl, N,N-dialkylcarbamyl, N-alkylcarbamyl-alkyl or N,N-dialkylcarbamylalkyl group, are useful as diuretics and saluretics; some derivatives possess secretolytic activity.

Abstract: 2-AMINOMETHYL-4,6-DIHALOGENPHENOL DERIVATIVES AND SALTS THEREOF WITH PHYSIOLOGICALLY ACCEPTABLE ACIDS OR BASES HAVING THE FORMULA: ##STR1## wherein X is the same halogen in both positions, R.sub.1 is a hydrogen atom or a lower alkyl group, R.sub.2 is an alkyl, cycloalkyl, aryl or aralkyl group, or R.sub.1 and R.sub.2 together with the nitrogen atom may form a saturated heterocyclic ring, which ring may be interrupted by an oxygen, nitrogen or sulfur atom, R.sub.3 is a hydrogen atom, an alkyl, alkoxyalkyl, carboxyalkyl, carbamylalkyl, aralkyl, acyl or sulfonyl group or a base radical, e.g. an alkali metal atom, and R.sub.3 " is a cyanoalkyl, hydroxyalkyl, carbalkoxy-alkyl, N,N-dialkylcarbamyl, N-alkylcarbamyl-alkyl or N,N-dialkylcarbamylalkyl group, are useful as diuretics and saluretics; some derivatives possess secretolytic activity.