Patents by Inventor Ludwig Paul Cooymans

Ludwig Paul Cooymans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,4-DIAMINOQUINAZOLINE DERIVATIVES AND MEDICAL USES THEREOF
    Publication number: 20230278964
    Abstract: This application relates to quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and medical uses thereof.
    Type: Application
    Filed: January 24, 2023
    Publication date: September 7, 2023
    Inventors: David Craig MC GOWAN, Werner Constant Johan EMBRECHTS, Jérôme Émile Georges GUILLEMONT, Ludwig Paul COOYMANS, Tim Hugo Maria JONCKERS, Pierre Jean-Marie RABOISSON
  • RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES
    Publication number: 20230203004
    Abstract: The invention concerns compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising these compounds and the compounds for use in the treatment of respiratory syncytial virus infection.
    Type: Application
    Filed: April 21, 2021
    Publication date: June 29, 2023
    Inventors: Sandrine Céline GROSSE, Jérôme Émile Georges GUILLEMONT, Pierre Jean-Marie Bernard RABOISSON, David Craig MC GOWAN, Werner Constant J. EMBRECHTS, Ludwig Paul COOYMANS, Tim Hugo Maria JONCKERS
  • 2,4-diaminoquinazoline derivatives and medical uses thereof
    Patent number: 11597704
    Abstract: This application relates to quinazoline derivatives of formula (I), pharmaceutical compositions comprising the compounds of formula (I), and the use of the compounds of formula (I) in the treatment or prevention of a viral infection, of a virus-induced disease, of cancer or of an allergy.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: March 7, 2023
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig Mc Gowan, Werner Constant Johan Embrechts, Jérôme Émile Georges Guillemont, Ludwig Paul Cooymans, Tim Hugo Maria Jonckers, Pierre Jean-Marie Raboisson
  • DIHYDROPYRANOPYRIMIDINES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20210387997
    Abstract: This invention relates to dihydropyranopyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: June 23, 2021
    Publication date: December 16, 2021
    Inventors: Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON, Jérôme Émile Georges GUILLEMONT, David Craig MC GOWAN, Werner Constant Johan EMBRECHTS, Ludwig Paul COOYMANS, Laurent CALMUS
  • Dihydropyranopyrimidines for the treatment of viral infections
    Patent number: 11053256
    Abstract: This invention relates to dihydropyranopynmidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: July 6, 2021
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Jérôme Émile Georges Guillemont, David Craig McGowan, Werner Constant Johan Embrechts, Ludwig Paul Cooymans, Laurent Calmus
  • 2,4-DIAMINOQUINAZOLINE DERIVATIVES AND MEDICAL USES THEREOF
    Publication number: 20210040046
    Abstract: This application relates to quinazoline derivatives of formula (I), pharmaceutical compositions comprising the compounds of formula (I), and the use of the compounds of formula (I) in the treatment or prevention of a viral infection, of a virus-induced disease, of cancer or of an allergy.
    Type: Application
    Filed: February 28, 2019
    Publication date: February 11, 2021
    Applicant: Janssen Sciences Ireland Unlimi
    Inventors: David Craig MC GOWAN, Werner Constant Johan EMBRECHTS, Jérôme Émile Georges GUILLEMONT, Ludwig Paul COOYMANS, Tim Hugo Maria JONCKERS, Pierre Jean-Marie RABOISSON
  • Heterocyclic indoles for use in influenza virus infection
    Patent number: 10626108
    Abstract: The current invention relates to a compound of formula (I) which can be used for the treatment of, or against viral influenza infections.
    Type: Grant
    Filed: November 25, 2016
    Date of Patent: April 21, 2020
    Assignee: JANSSEN SCIENCES IRELAND UC
    Inventors: Tim Hugo Maria Jonckers, David Craig McGowan, Jérôme Émile Georges Guilllemont, Ludwig Paul Cooymans, Werner Constant Johan Embrechts, Christophe Francis Robert Nestor Buyck, Wendy Mia Albert Balemans, Pierre Jean-Marie Bernard Raboisson
  • Indoles for use in influenza virus infection
    Patent number: 10597390
    Abstract: The invention relates to compounds having the structure of formula (I) which can be used for the treatment of or against influenza infections.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: March 24, 2020
    Assignee: Janssen Sciences Ireland UC
    Inventors: Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Jérôme Émile Georges Guillemont, David Craig McGowan, Werner Constant Johan Embrechts, Ludwig Paul Cooymans, Antoine Benjamin Michaut
  • DIHYDROPYRANOPYRIMIDINES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20190322678
    Abstract: This invention relates to dihydropyranopynmidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 24, 2019
    Applicant: Janssen Sciences Ireland Unlimited Company
    Inventors: Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON, Jérôme Émile Georges GUILLEMONT, David Craig MC GOWAN, Werner Constant Johan EMBRECHTS, Ludwig Paul COOYMANS, Laurent CALMUS
  • HETEROCYCLIC INDOLES FOR USE IN INFLUENZA VIRUS INFECTION
    Publication number: 20180258074
    Abstract: The current invention relates to a compound of formula (I) which can be used for the treatment of, or against viral influenza infections.
    Type: Application
    Filed: November 25, 2016
    Publication date: September 13, 2018
    Inventors: Tim Hugo Maria JONCKERS, David Craig MCGOWAN, Jérôme Émile George GUILLLEMONT, Ludwig Paul COOYMANS, Werner Constant Johan EMBRECHTS, Christophe Francis Robert Nest BUYCK, Wendy Mia Albert BALEMANS, Pierre Jean-Marie Bernard RABOISSON
  • Piperidine substituted pyrazolo[1,5-A]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV)
    Patent number: 9981976
    Abstract: The invention concerns novel substituted bicyclic pyrazolo pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: May 29, 2018
    Assignee: Janssen Sciences Ireland UC
    Inventors: Abdellah Tahari, Sandrine Marie Helene Vendeville, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Samuël Dominique Demin, Lili Hu, Ludwig Paul Cooymans
  • Indoles as respiratory syncytial virus antiviral agents
    Patent number: 9944638
    Abstract: Indoles having inhibitory activity on RSV replication and having the formula I the prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof; compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: April 17, 2018
    Assignee: JANSSEN SCIENCES IRELAND US
    Inventors: Ludwig Paul Cooymans, Samuël Dominique Demin, Lili Hu, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Abdellah Tahri, Sandrine Marie Helene Vendeville
  • Azaindoles as respiratory syncytial virus antiviral agents
    Patent number: 9896459
    Abstract: Azaindoles having inhibitory activity on RSV replication and having the formula I compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: February 20, 2018
    Assignee: Janssen Sciences Ireland UC
    Inventors: Ludwig Paul Cooymans, Samuël Dominique Demin, Lili Hu, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Abdellah Tahri, Sandrine Marie Helene Vendeville
  • Azabenzimidazoles as respiratory syncytial virus antiviral agents
    Patent number: 9890178
    Abstract: A compound satisfying formula I, a prodrug, N-oxide, addition salt, quaternary amine, metal complex, or a stereochemically isomeric form thereof; compositions contain these compounds as active ingredient and processes for preparing these compounds and compositions.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: February 13, 2018
    Assignee: Janssen Sciences Ireland UC
    Inventors: Ludwig Paul Cooymans, Samuël Dominique Demin, Lili Hu, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Abdellah Tahri, Sandrine Marie Helene Vendeville
  • 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents
    Patent number: 9845321
    Abstract: The present invention is concerned with novel 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles having formula (I) stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherein R4, R5, Z and Het have the meaning defined in the claims. The compounds according to the present invention are useful as inhibitors on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: December 19, 2017
    Assignee: Janssen Sciences Ireland UC
    Inventors: Abdellah Tahri, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Sandrine Marie Helene Vendeville, Lili Hu, Samuel Dominique Demin, Ludwig Paul Cooymans
  • PIPERIDINE SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES WITH INHIBITORY ACTIVITY ON THE REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)
    Publication number: 20170349591
    Abstract: The invention concerns novel substituted bicyclic pyrazolo pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
    Type: Application
    Filed: December 7, 2015
    Publication date: December 7, 2017
    Inventors: Abdellah TAHARI, Sandrine Marie Helene VENDEVILLE, Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON, Samuël Dominique DEMIN, Lili HU, Ludwig Paul COOYMANS
  • INDOLES FOR USE IN INFLUENZA VIRUS INFECTION
    Publication number: 20170226102
    Abstract: The invention relates to compounds having the structure of formula (I) which can be used for the treatment of or against influenza infections.
    Type: Application
    Filed: August 7, 2015
    Publication date: August 10, 2017
    Inventors: Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Jérôme Émile Georges Guillemont, David Craig Mc Gowan, Werner Constant Johan Embrechts, Ludwig Paul Cooymans, Antoine Benjamin Michaut
  • RSV antiviral compounds
    Patent number: 9617289
    Abstract: Inhibitors of RSV replication of formula RI including stereochemically isomeric forms, and salts or solvates thereof, wherein R22, W, Q, V, Z p, s, and Het have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other RSV inhibitors, in RSV therapy.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: April 11, 2017
    Assignee: JANSSEN SCIENCES IRELAND UC
    Inventors: Abdellah Tahri, Sandrine Marie Helene Vendeville, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Lili Hu, Samuël Dominique Demin, Ludwig Paul Cooymans
  • AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS
    Publication number: 20160251377
    Abstract: Azaindoles having inhibitory activity on RSV replication and having the formula I compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.
    Type: Application
    Filed: May 12, 2016
    Publication date: September 1, 2016
    Inventors: Ludwig Paul Cooymans, Samuël Dominique DEMIN, Lili HU, Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON, Abdellah TAHRI, Sandrine Marie Helene VENDEVILLE
  • INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS
    Publication number: 20160237083
    Abstract: Indoles having inhibitory activity on RSV replication and having the formula I the prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof; compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.
    Type: Application
    Filed: April 22, 2016
    Publication date: August 18, 2016
    Inventors: Ludwig Paul COOYMANS, Samuël Dominique DEMIN, Lili HU, Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON, Abdellah TAHRI, Sandrine Marie Helene VENDEVILLE