Abstract: A portable self-contained apparatus for delivery of cardiopulmonary resuscitation (CPR) including an arrangement for applying cyclical chest compression and a lung ventilator operatively connected to the chest compression arrangement to deliver volume control ventilation simultaneously with chest compression or asynchronously with chest compression after a predetermined number of compressions. Span adjustment for the thumper accommodates patients with different chest sizes and also adjusts the length of stroke and force of the chest compression thumper as well as the volume of the ventilator output. A ratchet connected to the thumper allows natural expansion of the chest during inhalation by the patient while allowing compression by the apparatus. A control arrangement allows selectively operating the chest compression thumper and the ventilator in a predetermined sequence as well as monitor a patient's vital signs.