Patents by Inventor Luigi Boltri

Luigi Boltri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9233105
    Abstract: The present invention provides a pharmaceutical composition comprising taste-masked immediate release microcapsules which comprise fexofenadine and a water-insoluble polymer coating. These microcapsules and the pharmaceutical compositions comprising them have suitable drug content and desirable pharmaceutical properties, including a quick dissolution rate of fexofenadine combined with a taste masking effect.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: January 12, 2016
    Assignee: Adare Pharmaceuticals S.R.L.
    Inventors: Luigi Mapelli, Flavio Fabiani, Luigi Boltri, Paolo Gatti, Mauro Serratoni, Roberto Cassanmagnago
  • Publication number: 20140322296
    Abstract: The present invention provides a microcapsule pharmaceutical composition of at least a bisquinoline drug. said microcapsule comprises a drug core of a pharmaceutically effective amount of a bisquinoline drug and a polymeric coating over the core. This microcapsule pharmaceutical composition has desirable pharmaceutical properties, including taste masking effect and a high stability.
    Type: Application
    Filed: March 21, 2014
    Publication date: October 30, 2014
    Inventors: Christian Stollberg, Giancarla Bianchi, Flavio Fabiani, Luigi Boltri
  • Publication number: 20140276632
    Abstract: The present invention provides a process for the preparation of a stable and homogeneous liquid composition that is suitable for enteral administration comprising a digestive enzyme product and nutrients from a nutritional formula having specific amount of nutrients. The invention further provides a method for efficiently and effectively administering a therapeutically effective dose of the stable and homogeneous liquid composition by means of an enteral tube.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Aptalis Pharma Ltd.
    Inventors: Vincenza PIRONTI, Emanuela RONDA, Luigi BOLTRI
  • Publication number: 20140141091
    Abstract: The present invention provides a pharmaceutical composition comprising taste-masked immediate release microcapsules which comprise fexofenadine and a water-insoluble polymer coating. These microcapsules and the pharmaceutical compositions comprising them have suitable drug content and desirable pharmaceutical properties, including a quick dissolution rate of fexofenadine combined with a taste masking effect.
    Type: Application
    Filed: October 9, 2013
    Publication date: May 22, 2014
    Applicant: APTALIS PHARMA LIMITED
    Inventors: Luigi Mapelli, Flavio Fabiani, Luigi Boltri, Paolo Gatti, Mauro Serratoni, Roberto Cassanmagnago
  • Patent number: 8722096
    Abstract: Lipoic acid pellets are described, obtained from inert cores externally coated with lipoic acid. The so obtained active cores are coated with a first layer of insulating polymeric material and then with a polymeric coat that is insoluble at the gastric pH. Pellet are then formulated pharmaceutically, for instance in jelly capsules or controlled release capsules or as oral suspensions, dispersible powders, sachets, etc.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: May 13, 2014
    Assignees: Aptalis Pharma Limited, Laboratorio Chimico Internazionale S.p.A.
    Inventors: Luigi Boltri, Flavio Fabiani, Luigi Mapelli, Annibale Salvi, Paolo Magri', Antonio Nardi, Flavio Villani
  • Publication number: 20140050797
    Abstract: The present invention is directed to pharmaceutical compositions and dosage forms comprising TPR beads, wherein said TPR beads comprise a solid dispersion of at least one active pharmaceutical ingredient in at least one solubility-enhancing polymer, and a TPR coating comprising a water insoluble polymer and an enteric polymer, wherein the active pharmaceutical ingredient comprises a weakly basic active pharmaceutical ingredient having a solubility of not more than 100 ?g/mL at pH 6.8.
    Type: Application
    Filed: June 6, 2013
    Publication date: February 20, 2014
    Inventors: Gopi VENKATESH, Luigi BOLTRI, Italo COLOMBO, Jin-Wang LAI, Flavio FABIANI, Luigi MAPELLI
  • Patent number: 8580313
    Abstract: The present invention provides a pharmaceutical composition comprising taste-masked immediate release microcapsules which comprise fexofenadine and a water-insoluble polymer coating. These microcapsules and the pharmaceutical compositions comprising them have suitable drug content and desirable pharmaceutical properties, including a quick dissolution rate of fexofenadine combined with a taste masking effect.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: November 12, 2013
    Assignee: Aptalis Pharma Limited
    Inventors: Luigi Mapelli, Flavio Fabiani, Luigi Boltri, Paolo Gatti, Mauro Serratoni, Roberto Cassanmagnago
  • Publication number: 20130274297
    Abstract: The invention provides a composite of drug, polymeric carrier and at least one not cross linked polymer useful to improve the solubility of poorly water soluble drugs. The present invention comprises manufacturing process of this composite material. The manufacturing process is carried out by the solvent induced activation process, wherein the not cross-linked polymer is loaded into the composite from organic solution, possibly together with the drug. Pharmaceutical compositions comprising said composite in combination with pharmaceutical acceptable excipients are also described herein.
    Type: Application
    Filed: December 22, 2011
    Publication date: October 17, 2013
    Applicant: APTALIS PHARMA LIMITED
    Inventors: Paolo Gatti, Italo Colombo, Dario Gervasoni, Vincenza Pironti, Lia Alborghetti, Flavio Fabiani, Luigi Boltri
  • Publication number: 20120201875
    Abstract: The present invention is directed to a pharmaceutical composition or dosage form having a stable, low (diluted) digestive enzyme content comprising at least one digestive enzyme and at least one carrier, or a dosage form thereof. The invention is also directed to a process of preparation of the composition or the dosage form. In addition the invention is directed to the treatment and prevention of disorders or conditions associated with a digestive enzyme deficiency in a patient in need thereof, comprising administering to said patient a pharmaceutically acceptable amount of the composition having a stable low digestive enzyme content or dosage form thereof.
    Type: Application
    Filed: October 3, 2011
    Publication date: August 9, 2012
    Applicant: Aptalis Pharma Limited
    Inventors: Giovanni ORTENZI, Giuseppe De Franza, Danilo Clementi, Christian Stollberg, Luigi Boltri
  • Publication number: 20110250281
    Abstract: The present invention provides a pharmaceutical composition comprising taste-masked immediate release microcapsules which comprise fexofenadine and a water-insoluble polymer coating. These microcapsules and the pharmaceutical compositions comprising them have suitable drug content and desirable pharmaceutical properties, including a quick dissolution rate of fexofenadine combined with a taste masking effect.
    Type: Application
    Filed: December 2, 2010
    Publication date: October 13, 2011
    Applicant: Eurand Pharmaceuticals Limited
    Inventors: Luigi Mapelli, Flavio Fabiani, Luigi Boltri, Paolo Gatti, Mauro Serratoni, Roberto Cassanmagnago
  • Publication number: 20110020442
    Abstract: The invention relates to an oral compositions comprising telithromycin that have taste masking properties, a process for the preparation thereof, and methods of using the composition.
    Type: Application
    Filed: October 7, 2010
    Publication date: January 27, 2011
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Philippe Becourt, Nicoletta Cioloca, Luigi Boltri, Stefano De Luigi Bruschi, Luigi Giovanni Mapelli, Leonardo Rabaglia, Detlev Schwabe
  • Publication number: 20090117232
    Abstract: Lipoic acid pellets are described, obtained from inert cores externally coated with lipoic acid. The so obtained active cores are coated with a first layer of insulating polymeric material and then with a polymeric coat that is insoluble at the gastric pH. Pellet are then formulated pharmaceutically, for instance in jelly capsules or controlled release capsules or as oral suspensions, dispersible powders, sachets, etc.
    Type: Application
    Filed: May 25, 2007
    Publication date: May 7, 2009
    Applicants: EURAND PHARMACEUTICALS LIMITED, LABORATORIO CHIMICO INTERNAZIONALE S.P.A.
    Inventors: Luigi Boltri, Flavio Fabiani, Luigi Mapelli, Annibale Salvi, Paolo Magri', Antonio Nardi, Flavio Villani
  • Publication number: 20080069878
    Abstract: The present invention is directed to pharmaceutical compositions and dosage forms comprising TPR beads, wherein said TPR beads comprise a solid dispersion of at least one active pharmaceutical ingredient in at least one solubility-enhancing polymer, and a TPR coating comprising a water insoluble polymer and an enteric polymer, wherein the active pharmaceutical ingredient comprises a weakly basic active pharmaceutical ingredient having a solubility of not more than 100 ?g/mL at pH 6.8.
    Type: Application
    Filed: August 29, 2007
    Publication date: March 20, 2008
    Inventors: Gopi Venkatesh, Luigi Boltri, Italo Colombo, Jin-Wang Lai, Flavio Flabiani, Luigi Mapelli
  • Publication number: 20070048385
    Abstract: Microcapsules containing an active ingredient, constituted by a core coated with a polymer membrane, characterized in that the active ingredient is incorporated in the polymer coating layer, and in that said layer is applied using microencapsulation techniques (coacervation by means of phase separation). The microcapsules; thus produced have excellent properties of taste masking and prolonged release of the active ingredients.
    Type: Application
    Filed: May 28, 2004
    Publication date: March 1, 2007
    Inventors: Roberto Golzi, Luigi Boltri, Christian Stollberg
  • Publication number: 20050269722
    Abstract: Process for the production of microcapsules containing a drug and comprising a layer of ethylcellulose and a layer of an acrylic polymer and microcapsules produced thereby.
    Type: Application
    Filed: July 17, 2002
    Publication date: December 8, 2005
    Inventors: Stefano De Luigi Brushci, Luigi Mapelli, Leonardo Rabaglia, Luigi Boltri
  • Publication number: 20040013737
    Abstract: The invention relates to an oral compositions comprising telithromycin that have taste masking properties, a process for the preparation thereof, and methods of using the compsition.
    Type: Application
    Filed: July 19, 2002
    Publication date: January 22, 2004
    Inventors: Philippe Becourt, Nicoletta Cioloca, Luigi Boltri, Stefano De Luigi Bruschi, Luigi Giovanni Mapelli, Leonardo Rabaglia, Detlev Schwabe
  • Patent number: 6107276
    Abstract: The pharmaceutical compositions including a slightly soluble drug incorporated in a water-swellable, but water-insoluble cross-linked polymer, a surface active agent, and an oil show much improved dissolution and, consequently, bioavailability in respect of the drug as is or used with a polymeric carrier of said type.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: August 22, 2000
    Assignee: Vectorpharma International S.p.A.
    Inventors: Fabio Carli, Daniela Lombardi, Pierandrea Esposito, Luca Dobetti, Luigi Boltri
  • Patent number: 5895789
    Abstract: A pharmaceutical composition for parenteral administration having anti-inflammatory and analgesic properties is disclosed which contain, as the active principle, alkylammonium salts of 2-arylpropionic acids.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: April 20, 1999
    Assignee: Dompe' SpA
    Inventors: Marco Gentile, Luigi Boltri, Gaetano Clavenna
  • Patent number: 5858330
    Abstract: The present invention relates to a topical formulation of gel-like consistency, but nebulizable by a mechanical pump, containing colloidal silices as gelifying agent.
    Type: Grant
    Filed: March 18, 1996
    Date of Patent: January 12, 1999
    Assignee: Dompe' S.p.A.
    Inventors: Luigi Boltri, Antonietta Coppola, Marco Gentile, Gaetano Clavenna