Patents by Inventor Luigi Maria LONGO

Luigi Maria LONGO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240398699
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Application
    Filed: May 30, 2024
    Publication date: December 5, 2024
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Luigi Maria LONGO
  • Publication number: 20240299551
    Abstract: The invention provides a composition for use as a delivery vehicle comprising at least one thermo-responsive polymer (polymer A) and at least one ion-sensitive polymer (polymer B) in a liquid formulation. Polymer A is preferably a polyoxyethylene-poly-oxypropylene block copolymer or a cellulose derivative. Polymer B is preferably a polysaccharide. The composition can include an active substance for delivery or can be used as a delivery vehicle for a substance added at the time of administration such as mesenchymal stem cells.
    Type: Application
    Filed: May 17, 2024
    Publication date: September 12, 2024
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Franca FERRARI, Cristina BONFERONI, Giuseppina SANDRI, Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI
  • Patent number: 12036316
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Grant
    Filed: December 27, 2022
    Date of Patent: July 16, 2024
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Moro, Luigi Maria Longo
  • Patent number: 12011483
    Abstract: The invention provides a composition for use as a delivery vehicle comprising at least one thermo-responsive polymer (polymer A) and at least one ion-sensitive polymer (polymer B) in a liquid formulation. Polymer A is preferably a polyoxyethylene-polyoxypropylene block copolymer or a cellulose derivative. Polymer B a polysaccharide. The composition can include an active substance for delivery or can be used as a delivery vehicle for a substance added at the time of administration such as mesenchymal stem cells.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: June 18, 2024
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Franca Ferrari, Cristina Bonferoni, Giuseppina Sandri, Luigi Maria Longo, Cristina Macelloni, Silvia Rossi
  • Publication number: 20240189324
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Application
    Filed: December 14, 2023
    Publication date: June 13, 2024
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria LONGO
  • Patent number: 11883415
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: January 30, 2024
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • Publication number: 20230135346
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Application
    Filed: December 27, 2022
    Publication date: May 4, 2023
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Luigi Maria LONGO
  • Patent number: 11564883
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: January 31, 2023
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Moro, Luigi Maria Longo
  • Publication number: 20220193093
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Application
    Filed: November 23, 2021
    Publication date: June 23, 2022
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria LONGO
  • Patent number: 11213531
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: January 4, 2022
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • Patent number: 11123460
    Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: September 21, 2021
    Assignee: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Maria Longo, Luigi Moro, Enrico Frimonti, Alessandro Repici
  • Publication number: 20210154300
    Abstract: The invention provides a composition for use as a delivery vehicle comprising at least one thermo-responsive polymer (polymer A) and at least one ion-sensitive polymer (polymer B) in a liquid formulation. Polymer A is preferably a polyoxyethylene-polyoxypropylene block copolymer or a cellulose derivative. Polymer B a polysaccharide. The composition can include an active substance for delivery or can be used as a delivery vehicle for a substance added at the time of administration such as mesenchymal stem cells.
    Type: Application
    Filed: December 20, 2018
    Publication date: May 27, 2021
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Franca FERRARI, Cristina BONFERONI, Giuseppina SANDRI, Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI
  • Patent number: 10980819
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: April 20, 2021
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • Patent number: 10925978
    Abstract: The present invention provides a novel liquid composition in the form of an emulsion or microemulsion for rectal administration comprising at least one dye, at least one emulsifier, and at least one physiologically acceptable excipient, and its use in a diagnostic endoscopic procedure of sigmoid colon and/or rectum. Preferably, said diagnostic endoscopic procedure of sigmoid colon and/or rectum is an anoscopy, a proctoscopy, a rectoscopy and/or a sigmoidoscopy.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: February 23, 2021
    Assignee: COSMO TECHNOLOGIES LIMITED
    Inventors: Luigi Moro, Enrico Frimonti, Luigi Maria Longo
  • Publication number: 20210007993
    Abstract: The present invention provides an innovative combination of biomaterials, multifunctional polymers, able to structure themselves at the site of action. The innovative combination of biomaterials of the invention is formulated in a solid composition and can be used as a versatile delivery vehicle or carrier in many pharmaceutical fields. The solid composition comprising the combination of biomaterials of the invention is provided to target delivery for medical purposes in humans.
    Type: Application
    Filed: December 20, 2018
    Publication date: January 14, 2021
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI, Franca FERRARI
  • Patent number: 10849979
    Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: December 1, 2020
    Assignee: COSMO TECHNOLOGIES LIMITED
    Inventors: Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
  • Publication number: 20200281850
    Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.
    Type: Application
    Filed: November 7, 2018
    Publication date: September 10, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi MORO, Luigi Maria LONGO
  • Publication number: 20200222429
    Abstract: The present disclosure provides high concentration formulations of cortexolone-I 7u-propionate suitable for treating 0 alopecia.
    Type: Application
    Filed: March 24, 2020
    Publication date: July 16, 2020
    Applicant: Cassiopea S.P.A.
    Inventor: Luigi Maria LONGO
  • Patent number: 10603327
    Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: March 31, 2020
    Assignee: Cassiopea S.P.A.
    Inventor: Luigi Maria Longo
  • Publication number: 20200054797
    Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 20, 2020
    Applicant: COSMO TECHNOLOGIES LTD.
    Inventors: Luigi Maria LONGO, Luigi MORO, Enrico FRIMONTI, Alessandro REPICI