Patents by Inventor Luigi Maria LONGO
Luigi Maria LONGO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240398699Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: ApplicationFiled: May 30, 2024Publication date: December 5, 2024Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Luigi Maria LONGO
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Publication number: 20240299551Abstract: The invention provides a composition for use as a delivery vehicle comprising at least one thermo-responsive polymer (polymer A) and at least one ion-sensitive polymer (polymer B) in a liquid formulation. Polymer A is preferably a polyoxyethylene-poly-oxypropylene block copolymer or a cellulose derivative. Polymer B is preferably a polysaccharide. The composition can include an active substance for delivery or can be used as a delivery vehicle for a substance added at the time of administration such as mesenchymal stem cells.Type: ApplicationFiled: May 17, 2024Publication date: September 12, 2024Applicant: COSMO TECHNOLOGIES LTD.Inventors: Franca FERRARI, Cristina BONFERONI, Giuseppina SANDRI, Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI
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Patent number: 12036316Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: GrantFiled: December 27, 2022Date of Patent: July 16, 2024Assignee: COSMO TECHNOLOGIES LTD.Inventors: Luigi Moro, Luigi Maria Longo
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Patent number: 12011483Abstract: The invention provides a composition for use as a delivery vehicle comprising at least one thermo-responsive polymer (polymer A) and at least one ion-sensitive polymer (polymer B) in a liquid formulation. Polymer A is preferably a polyoxyethylene-polyoxypropylene block copolymer or a cellulose derivative. Polymer B a polysaccharide. The composition can include an active substance for delivery or can be used as a delivery vehicle for a substance added at the time of administration such as mesenchymal stem cells.Type: GrantFiled: December 20, 2018Date of Patent: June 18, 2024Assignee: COSMO TECHNOLOGIES LTD.Inventors: Franca Ferrari, Cristina Bonferoni, Giuseppina Sandri, Luigi Maria Longo, Cristina Macelloni, Silvia Rossi
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Publication number: 20240189324Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.Type: ApplicationFiled: December 14, 2023Publication date: June 13, 2024Applicant: Cassiopea S.P.A.Inventor: Luigi Maria LONGO
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Patent number: 11883415Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.Type: GrantFiled: November 23, 2021Date of Patent: January 30, 2024Assignee: Cassiopea S.P.A.Inventor: Luigi Maria Longo
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Publication number: 20230135346Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: ApplicationFiled: December 27, 2022Publication date: May 4, 2023Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Luigi Maria LONGO
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Patent number: 11564883Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: GrantFiled: November 7, 2018Date of Patent: January 31, 2023Assignee: COSMO TECHNOLOGIES LTD.Inventors: Luigi Moro, Luigi Maria Longo
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Publication number: 20220193093Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.Type: ApplicationFiled: November 23, 2021Publication date: June 23, 2022Applicant: Cassiopea S.P.A.Inventor: Luigi Maria LONGO
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Patent number: 11213531Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.Type: GrantFiled: March 24, 2020Date of Patent: January 4, 2022Assignee: Cassiopea S.P.A.Inventor: Luigi Maria Longo
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Patent number: 11123460Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.Type: GrantFiled: October 25, 2019Date of Patent: September 21, 2021Assignee: COSMO TECHNOLOGIES LTD.Inventors: Luigi Maria Longo, Luigi Moro, Enrico Frimonti, Alessandro Repici
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Publication number: 20210154300Abstract: The invention provides a composition for use as a delivery vehicle comprising at least one thermo-responsive polymer (polymer A) and at least one ion-sensitive polymer (polymer B) in a liquid formulation. Polymer A is preferably a polyoxyethylene-polyoxypropylene block copolymer or a cellulose derivative. Polymer B a polysaccharide. The composition can include an active substance for delivery or can be used as a delivery vehicle for a substance added at the time of administration such as mesenchymal stem cells.Type: ApplicationFiled: December 20, 2018Publication date: May 27, 2021Applicant: COSMO TECHNOLOGIES LTD.Inventors: Franca FERRARI, Cristina BONFERONI, Giuseppina SANDRI, Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI
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Patent number: 10980819Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.Type: GrantFiled: August 1, 2019Date of Patent: April 20, 2021Assignee: Cassiopea S.P.A.Inventor: Luigi Maria Longo
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Patent number: 10925978Abstract: The present invention provides a novel liquid composition in the form of an emulsion or microemulsion for rectal administration comprising at least one dye, at least one emulsifier, and at least one physiologically acceptable excipient, and its use in a diagnostic endoscopic procedure of sigmoid colon and/or rectum. Preferably, said diagnostic endoscopic procedure of sigmoid colon and/or rectum is an anoscopy, a proctoscopy, a rectoscopy and/or a sigmoidoscopy.Type: GrantFiled: January 29, 2015Date of Patent: February 23, 2021Assignee: COSMO TECHNOLOGIES LIMITEDInventors: Luigi Moro, Enrico Frimonti, Luigi Maria Longo
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Publication number: 20210007993Abstract: The present invention provides an innovative combination of biomaterials, multifunctional polymers, able to structure themselves at the site of action. The innovative combination of biomaterials of the invention is formulated in a solid composition and can be used as a versatile delivery vehicle or carrier in many pharmaceutical fields. The solid composition comprising the combination of biomaterials of the invention is provided to target delivery for medical purposes in humans.Type: ApplicationFiled: December 20, 2018Publication date: January 14, 2021Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI, Franca FERRARI
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Patent number: 10849979Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.Type: GrantFiled: August 9, 2019Date of Patent: December 1, 2020Assignee: COSMO TECHNOLOGIES LIMITEDInventors: Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
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Publication number: 20200281850Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: ApplicationFiled: November 7, 2018Publication date: September 10, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Luigi Maria LONGO
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Publication number: 20200222429Abstract: The present disclosure provides high concentration formulations of cortexolone-I 7u-propionate suitable for treating 0 alopecia.Type: ApplicationFiled: March 24, 2020Publication date: July 16, 2020Applicant: Cassiopea S.P.A.Inventor: Luigi Maria LONGO
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Patent number: 10603327Abstract: The present disclosure provides high concentration formulations of cortexolone-17?-propionate suitable for treating alopecia.Type: GrantFiled: June 20, 2016Date of Patent: March 31, 2020Assignee: Cassiopea S.P.A.Inventor: Luigi Maria Longo
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Publication number: 20200054797Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.Type: ApplicationFiled: October 25, 2019Publication date: February 20, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi Maria LONGO, Luigi MORO, Enrico FRIMONTI, Alessandro REPICI