Patents by Inventor Luigi Nicolais

Luigi Nicolais has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8658147
    Abstract: The invention relates to a method for the preparation of a polymer hydrogel, comprising cross-linking a precursor comprising a hydrophilic polymer optionally in combination with a second hydrophilic polymer, using a polycarboxylic acid as the cross-linking agent. The invention further concerns the polymer hydrogel obtainable by the method of the invention and the use thereof in a number of different applications.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: February 25, 2014
    Assignee: Gelesis LLC
    Inventors: Alessandro Sannino, Luigi Ambrosio, Luigi Nicolais, Christian Demitri
  • Patent number: 7976745
    Abstract: The present invention relates to a process for the preparation of a composite polymeric material containing nanometric inorganic inclusions comprising the steps of: mixing a polymer with a thermolytic precursor to provide a homogeneous dispersion of said at least one precursor and of said at least one polymer; subjecting said homogeneous dispersion to heating to provide a molten polymer and thermolytic fission of the precursor, generating the inclusions dispersed in the molten polymer.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: July 12, 2011
    Assignees: STMicroelectronics S.r.l., Universita degli Studi di Napoli Federico II
    Inventors: Raffaele Vecchione, Gianfranco Carotenuto, Valeria Casuscelli, Floriana Esposito, Salvatore Leonardi, Luigi Nicolais, Maria Viviana Volpe
  • Publication number: 20110027364
    Abstract: A method of producing a soybean-based biomaterial which is suitable for use in a biomedical product, the method comprising: defatting soy flour; either prior to or at the same time as, performing a solvent extraction; to produce a biomaterial comprising variable levels of soy proteins, carbohydrates and isoflavones. The resulting biomaterials have a range of biomedical uses and are particularly desirable because of their isoflavone content. Examples of biomedical products containing the biomaterials include wound dressings; scaffolds for tissue engineering; fillers or implants for use in surgery; temporary barriers for use in dental or surgical procedures or to prevent post-surgical tissue adherence; carriers for the delivery of drugs, bioactive peptides or plasmids; anti-inflammatory agents; coatings for wound dressings or for dental, medical, surgical or veterinary devices or implants; and compositions for soothing skin or gum irritation.
    Type: Application
    Filed: November 26, 2008
    Publication date: February 3, 2011
    Applicant: UNIVERSITY OF BRIGHTON
    Inventors: Luigi Ambrosio, Luigi Nicolais, Jonathan Peter Salvage, Matteo Santin, Guy Standen
  • Publication number: 20100234233
    Abstract: The invention relates to a method for the preparation of a polymer hydrogel, comprising cross-linking a precursor comprising a hydrophilic polymer optionally in combination with a second hydrophilic polymer, using a polycarboxylic acid as the cross-linking agent. The invention further concerns the polymer hydrogel obtainable by the method of the invention and the use thereof in a number of different applications.
    Type: Application
    Filed: February 10, 2010
    Publication date: September 16, 2010
    Inventors: Alessandro Sannino, Luigi Ambrosio, Luigi Nicolais
  • Patent number: 7695543
    Abstract: The present invention relates to a process for the production of continuous silver wires having micrometric or sub-micrometric diameter comprising a step of thermal decomposition of silver dodecyl-mercaptide in the presence of metallic aluminum.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: April 13, 2010
    Assignee: C.R.F. Societa Consortile per Azioni
    Inventors: Brunetto Martorana, Luigi Nicolais, Gianfranco Carotenuto, Piero Perlo
  • Publication number: 20080227944
    Abstract: The invention relates to a method for the preparation of a superabsorbent polymer hydrogel, comprising the steps of (i) crosslinking a 3% overall aqueous solution of carboxymethylcellulose sodium salt and hydroxyethylcellulose with 5% carbodiimide, in the presence of an acid catalyst; (ii) washing the gel obtained at least once by swelling in a polar organic solvent; and (iii) drying the gel by phase inversion in a non-solvent for cellulose. The invention further concerns the superabsorbent hydrogels obtainable by said method and the uses thereof.
    Type: Application
    Filed: December 28, 2005
    Publication date: September 18, 2008
    Inventors: Luigi Ambrosio, Luigi Nicolais, Alessandro Sannino
  • Patent number: 7329700
    Abstract: The method for the production of polymer/metal or metal sulphide composites comprises the stages of: preparing a dispersion of a metal mercaptide in a polymer, the metal of the mercaptide being selected from the group comprising the transition metals and earth metals, and heating the said dispersion so as to cause thermal decomposition of the mercaptide and obtain the corresponding metal or metal sulphide in the form of inclusions in a polymer matrix.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: February 12, 2008
    Assignee: CRF Societa Consortile per Azioni
    Inventors: Gianfranco Carotenuto, Luigi Nicolais, Pietro Perlo, Brunetto Martorana
  • Publication number: 20070293613
    Abstract: The method for the production of polymer/metal or metal sulphide composites comprises the stages of: preparing a dispersion of a metal mercaptide in a polymer, the metal of the mercaptide being selected from the group comprising the transition metals and earth metals, and heating the said dispersion so as to cause thermal decomposition of the mercaptide and obtain the corresponding metal or metal sulphide in the form of inclusions in a polymer matrix.
    Type: Application
    Filed: June 18, 2004
    Publication date: December 20, 2007
    Inventors: Gianfranco Carotenuto, Luigi Nicolais, Pietro Perlo, Brunetto Martorana
  • Publication number: 20060260720
    Abstract: The present invention relates to a process for the production of continuous silver wires having a micrometric or sub-micrometric diameter comprising a step of thermal decomposition of silver dodecyl-mercaptide in the presence of metallic aluminium.
    Type: Application
    Filed: March 8, 2006
    Publication date: November 23, 2006
    Applicant: C.R.F. Societa Consortile per Azioni
    Inventors: Brunetto Martorana, Luigi Nicolais, Gianfranco Carotenuto, Piero Perlo
  • Patent number: 7071327
    Abstract: A superabsorbent polysaccharide can be obtained by crosslinking a polysaccharide or derivative thereof with at least 1% by weight of a flexible spacer having a chain length of at least 9 chain atoms and having terminal activated coupling groups. The flexible spacer may comprise a polyalkyleneglycol with a molecular weight from about 400 to 10,000. The coupling groups may be provided by divinyl sulphone units.
    Type: Grant
    Filed: March 9, 2001
    Date of Patent: July 4, 2006
    Assignee: SCA Hygiene Products AB
    Inventors: Guiseppe Mensitieri, Fabrizio Porro, Luigi Nicolais, Alessandro Sannino
  • Publication number: 20060121262
    Abstract: The present invention relates to a process for the preparation of a composite polymeric material containing nanometric inorganic inclusions comprising the steps of: mixing a polymer with a thermolytic precursor to provide a homogeneous dispersion of said at least one precursor and of said at least one polymer; subjecting said homogeneous dispersion to heating to provide a molten polymer and thermolytic fission of the precursor, generating the inclusions dispersed in the molten polymer.
    Type: Application
    Filed: November 4, 2005
    Publication date: June 8, 2006
    Applicants: STMicroelectronics S.r. I, Universita degli Studi di Napoli Federico II
    Inventors: Raffaele Vecchione, Gianfranco Carotenuto, Valeria Casuscelli, Floriana Esposito, Salvatore Leonardi, Luigi Nicolais, Maria Volpe
  • Publication number: 20050031927
    Abstract: A polyelectrolyte membrane includes at least one syndiotactic styrenic polymer or copolymer in its clathrate form. The syndiotactic styrenic polymer or copolymer in its clathrate form is syndiotactic polystyrene. The polyelectrolyte membrane has a good electrical conductivity as well as good mechanical properties. This type of membrane is used for fuel cells and similar electrochemical applications.
    Type: Application
    Filed: June 29, 2004
    Publication date: February 10, 2005
    Applicant: STMicroelectronics S.r.l.
    Inventors: Teresa Napolitano, Salvatore Coffa, Giuseppe Mensitieri, Anna Borriello, Luigi Nicolais
  • Publication number: 20040081698
    Abstract: The invention provides thermoplastic materials for biomedical applications through the processing of soybean de-fatted Tofu cheese. The material films show a relatively high degree of water uptake from the dry state as well as good tensile strength and elastic modulus when tested in wet conditions. The materials minimise in vitro the humoral and cell-mediated inflammatory response, promote the formation of calcium phosphate crystals and undergo a slow degradation in buffer systems. Adhesion and proliferation of tissue cells are favoured by this natural composite material.
    Type: Application
    Filed: June 9, 2003
    Publication date: April 29, 2004
    Inventors: Matteo Santin, Luigi Nicolais, Luigi Ambrosio
  • Publication number: 20030149263
    Abstract: A superabsorbent polysaccharide can be obtained by crosslinking a polysaccharide or derivative thereof with at least 1% by weight of a flexible spacer having a chain length of at least 9 chain atoms and having terminal activated coupling groups. The flexible spacer may comprise a polyalkyleneglycol with a molecular weight from about 400 to 10,000. The coupling groups may be provided by divinyl sulphone units.
    Type: Application
    Filed: December 27, 2002
    Publication date: August 7, 2003
    Inventors: Guiseppee Mensitieri, Fabrizio Porrro, Luigi Nicolais, Alessandro Sannino
  • Patent number: 5645592
    Abstract: Provided are orthopedic fasteners and replacements such as nails, screws, pins, hip and knee replacements, etc., coated with hydrogels and other biocompatible/biodegradable materials which expand in the presence of liquids. Swelling of such coatings causes the fastener or replacement to be securely fixed into position once inserted into bone material. Useful coating materials include methacrylates, hyaluronic acid esters, and crosslinked esters of hyaluronic acid resulting from the esterification of hyaluronic acid with polyhydric alcohols. Also provided is a method for fixing a bone or bone replacement in position employing such coated orthopedic fasteners or replacements.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: July 8, 1997
    Assignee: M.U.R.S.T. Italian Ministry for Universities and Scientific and Technological Research
    Inventors: Luigi Nicolais, Luigi Ambrosio, Paolo Antonio Netti, Lanfranco Callegaro
  • Patent number: 4931325
    Abstract: This invention relates to composite manufactured articles formed by a set of uniaxially oriented isotatic polypropylene films, having a resistance to delamination of at least 0.4 kg/cm are prepared by heating under pressure a plurality of isotatic polypropylene films superimposed to each other and separated from each other by a non oriented polypropylene films. The oriented films show an orientation of the crystalline phase such as to produce X-ray scattering angles .DELTA..times. equal to or lower than 10.degree.. The non oriented film show an orientation of the crystalline phase such as to produce X-ray scattering angles higher than 20.degree., at a temperature between a temperature equal to or higher than the melting temperature, measured in non restrain conditions, of the non oriented film and a temperature lower than the melting temperature, measured in restrained conditions, of the oriented films.
    Type: Grant
    Filed: December 21, 1987
    Date of Patent: June 5, 1990
    Assignee: Montedison S.p.A.
    Inventors: Paolo Corradini, Claudio De Rosa, Gaetano Guerra, Luigi Nicolais, Vittorio Petraccone, Giancarlo Attalla