Patents by Inventor Luis A. Costa

Luis A. Costa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of improving yield of chlorine dioxide generation processes
    Publication number: 20020037248
    Abstract: A greater yield of chlorine dioxide from a chlorine dioxide generating process is obtained by providing acidic or acidity-generating components in the product chlorine dioxide solution to provide a chlorine dioxide solution having a pH below about 5.5.
    Type: Application
    Filed: January 31, 2001
    Publication date: March 28, 2002
    Inventors: Edward J. Bechberger, Mario Luis Costa, Marek Lipsztajn
  • Crotoxin complex as cytotoxic agent
    Patent number: 5164196
    Abstract: The present invention provides a stable composition of matter based on the cytotoxic activity of a basic phospholipase A.sub.2 of molecular weight 14,500 and isoelectric point 9.6-9.7 (crotoxin B) isolated from the venom of Crotalus durissus terrificus which in complex with a specific, non-enzymatic, peptide of molecular weight 9,500 and isoelectric point 3.5-3.7 (crotoxin A) displays a preferential cytotoxic activity against various types of tumor cells. When administered parenterally in an acceptable vehicle and in pharmacologically efficient amounts to animals and humans the complex is useful in the treatment of malignant tumors in advanced stages. The method for purification of the active components, the preparation in a pharmacologically acceptable form, and the method of therapeutic use of the present composition of matter are also disclosed.
    Type: Grant
    Filed: January 3, 1990
    Date of Patent: November 17, 1992
    Assignee: Ventech Research, Inc.
    Inventors: Guillermo J. H. Plata, Luis A. Costa, Carlos M. Coni, Juan C. Vidal