Patents by Inventor Luis A. Pardo

Luis A. Pardo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7910100
    Abstract: The present invention relates to a particularly advantageous antibody, antibody fragment or derivative thereof, which specifically binds to/interacts with at least one epitope of the extracellular or intracellular domain or the mammalian EAG1 ion channel and to nucleic acid molecules encoding these anti-EAG1 antibodies, antibody fragments or derivatives and to vectors comprising such nucleic acid molecules. The invention additionally relates to methods for the preparation of such anti-EAG1 antibodies, antibody fragments or derivatives thereof, pharmaceutical compositions comprising these antibodies, antibody fragments or derivatives, and methods of using the antibodies, antibody fragments or derivatives or the compositions for a variety of purposes, such as diagnosing disease, treating disease, assessing for the presence of EAG1-expressing cells, or blocking EAG1 function in cells.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: March 22, 2011
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissen
    Inventors: Walter Stühmer, Hendrik Knötgen, David Gómez-Varela, Luis A. Pardo, Mike Rothe, Esther Zwick-Wallasch, Kerstin Dehne
  • Publication number: 20090028851
    Abstract: The present invention relates to a particularly advantageous antibody, antibody fragment or derivative thereof, which specifically binds to/interacts with at least one epitope of the extracellular or intracellular domain or the mammalian EAG1 ion channel and to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to methods for the preparation of said antibody, antibody fragments or derivatives thereof and to pharmaceutical compositions comprising the same. Furthermore, the use of said antibody, antibody fragment or derivative thereof and also diagnostic compositions comprising said components are disclosed in the specification. The invention also relates to a method of assessing for the presence of EAG1 expressing cells and for a method of blocking EAG1 function in said cells. The invention further relates to a method of treating diseases with the help or said antibody or antibody fragment or derivative thereof.
    Type: Application
    Filed: October 4, 2005
    Publication date: January 29, 2009
    Applicants: MAXPLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCH, U3 PHARMA AG
    Inventors: Walter Stuhmer, Hendrik Knotgen, David Gomez-Varela, Luis A. Pardo, Mike Rothe, Esther Zwick-Wallasch, Kerstin Dehne
  • Patent number: 7364845
    Abstract: The present invention relates to a novel human K+ ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: April 29, 2008
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften, E.V.
    Inventors: Luis A Pardo-Fernandez, Walter Stuhmer, Synnove Beckh, Andrea Bruggemann, Donato Del Camino Fernandez-Miranda, Araceli Sanchez Perez, Rudiger Weseloh
  • Patent number: 7364730
    Abstract: The present invention relates to a novel human K+ ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: April 29, 2008
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften, E.V.
    Inventors: Luis A Pardo-Fernandez, Walter Stuhmer, Synnove Beckh, Andrea Bruggemann, Donato Del Camino Fernandez-Miranda, Araceli Sanchez Perez, Rudiger Weseloh
  • Patent number: 7314914
    Abstract: The present invention relates to a novel human K+ ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: January 1, 2008
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften, E.V.
    Inventors: Luis A Pardo-Fernandez, Walter Stuhmer, Synnove Beckh, Andrea Bruggemann, Donato Del Camino Fernandez-Miranda, Araceli Sanchez Perez, Rudiger Weseloh
  • Patent number: 7129207
    Abstract: The present invention relates to a novel human K+ ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: October 31, 2006
    Assignee: Max-Planck-Gesellschaft zur Forderung Wissenschaften e.V.
    Inventors: Luis A Pardo-Fernandez, Walter Stuhmer, Synnove Beckh, Andrea Bruggemann, Donato Del Camino Fernandez-Miranda, Araceli Sanchez Perez, Rudiger Weseloh