Patents by Inventor Luis Alfonso Rojas Expósito

Luis Alfonso Rojas Expósito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADENOVIRUS COMPRISING AN ALBUMIN-BINDING MOIETY
    Publication number: 20230331786
    Abstract: The invention relates to a recombinant adenovirus comprising an albumin-binding moiety on the outer surface of the adenoviral hexon protein, pharmaceutical compositions containing it and its medical use. Particularly, the invention relates to an oncolytic adenovirus comprising a sequence encoding an albumin-binding moiety inserted in the hypervariable region 1 (HVR1) of the hexon protein coding sequence and its use in the prevention and/or treatment of cancer.
    Type: Application
    Filed: January 10, 2023
    Publication date: October 19, 2023
    Inventors: Ramon Alemany Bonastre, Luis Alfonso Rojas Expósito
  • Adenovirus comprising an albumin-binding moiety
    Patent number: 11578104
    Abstract: The invention relates to a recombinant adenovirus comprising an albumin-binding moiety on the outer surface of the adenoviral hexon protein, pharmaceutical compositions containing it and its medical use. Particularly, the invention relates to an oncolytic adenovirus comprising a sequence encoding an albumin-binding moiety inserted in the hypervariable region 1 (HVR1) of the hexon protein coding sequence and its use in the prevention and/or treatment of cancer.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: February 14, 2023
    Assignees: Fundació Institut D'lnvestigació Biomedica De Bellvitge (í DIBELL), INSTITUT CATALA D'ONCOLOGIA (ICO)
    Inventors: Ramon Alemany Bonastre, Luis Alfonso Rojas Expósito
  • ADENOVIRUS COMPRISING AN ALBUMIN-BINDING MOIETY
    Publication number: 20200181208
    Abstract: The invention relates to a recombinant adenovirus comprising an albumin-binding moiety on the outer surface of the adenoviral hexon protein, pharmaceutical compositions containing it and its medical use. Particularly, the invention relates to an oncolytic adenovirus comprising a sequence encoding an albumin-binding moiety inserted in the hypervariable region 1 (HVR1) of the hexon protein coding sequence and its use in the prevention and/or treatment of cancer.
    Type: Application
    Filed: February 19, 2020
    Publication date: June 11, 2020
    Inventors: Ramon Alemany Bonastre, Luis Alfonso Rojas Expósito
  • Adenovirus comprising an albumin-binding moiety
    Patent number: 10604549
    Abstract: The invention relates to a recombinant adenovirus comprising an albumin-binding moiety on the outer surface of the adenoviral hexon protein, pharmaceutical compositions containing it and its medical use. Particularly, the invention relates to an oncolytic adenovirus comprising a sequence encoding an albumin-binding moiety inserted in the hypervariable region 1 (HVR1) of the hexon protein coding sequence and its use in the prevention and/or treatment of cancer.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: March 31, 2020
    Assignees: FUNDACIÓ INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE BELLVITGE (IDIBELL), INSTITUT CATALÀ D'ONCOLOGIA (ICO)
    Inventors: Ramon Alemany Bonastre, Luis Alfonso Rojas Expósito
  • ADENOVIRUS COMPRISING AN ALBUMIN-BINDING MOIETY
    Publication number: 20170051022
    Abstract: The invention relates to a recombinant adenovirus comprising an albumin-binding moiety on the outer surface of the adenoviral hexon protein, pharmaceutical compositions containing it and its medical use. Particularly, the invention relates to an oncolytic adenovirus comprising a sequence encoding an albumin-binding moiety inserted in the hypervariable region 1 (HVR1) of the hexon protein coding sequence and its use in the prevention and/or treatment of cancer.
    Type: Application
    Filed: April 30, 2015
    Publication date: February 23, 2017
    Inventors: Ramon Alemany Bonastre, Luis Alfonso Rojas Expósito