Patents by Inventor Luis E. Martinez

Luis E. Martinez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of quinones and phenols on solid support
    Patent number: 7226661
    Abstract: Generally, and in one form, the present invention is a method of making a benzene-modified compound on solid support that includes the steps of forming an (oxy)(aryl)carbene complex, esterifying the (oxy)(aryl)carbene complex to form an (ester)(aryl)carbene complex, and contacting the (ester)(aryl)carbene complex with a solid support such that the (ester)(aryl)carbene complex is bound to the solid support. In another form, the present invention includes compositions for the resulting (ester)(aryl)carbene complexes on solid support, such as any resulting solid support compounds formed after the initial coupling as well as those from any subsequent reaction, including those with linkers and on a solid support. The method and compositions of the present invention yield stable, durable, highly efficient and cost-effective as well as potentially biologically active lead compounds on solid support.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: June 5, 2007
    Assignee: Board of Regents, the University of Texas System
    Inventor: Luis E. Martinez
  • Synthesis of quinones and phenols on solid support
    Publication number: 20040151908
    Abstract: Generally, and in one form, the present invention is a method of making a benzene-modified compound on solid support that includes the steps of forming an (oxy)(aryl)carbene complex, esterifying the (oxy)(aryl)carbene complex to form an (ester)(aryl)carbene complex, and contacting the (ester)(aryl)carbene complex with a solid support such that the (ester)(aryl)carbene complex is bound to the solid support. In another form, the present invention includes compositions for the resulting (ester)(aryl)carbene complexes on solid support, such as any resulting solid support compounds formed after the initial coupling as well as those from any subsequent reaction, including those with linkers and on a solid support. The method and compositions of the present invention yield stable, durable, highly efficient and cost-effective as well as potentially biologically active lead compounds on solid support.
    Type: Application
    Filed: February 3, 2003
    Publication date: August 5, 2004
    Inventor: Luis E. Martinez
  • Stereoselective ring opening reactions
    Patent number: 5929232
    Abstract: The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic chiral catalyst to produce a stereoisomerically or regioselectively enriched product.
    Type: Grant
    Filed: March 25, 1996
    Date of Patent: July 27, 1999
    Assignee: President and Fellows of Harvard College
    Inventors: Eric N. Jacobsen, James L. Leighton, Luis E. Martinez
  • Stereoselective ring opening reactions
    Patent number: 5665890
    Abstract: The present invention relates a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic chiral catalyst to produce a steroisomerically or regioselectively enriched product.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: September 9, 1997
    Assignee: President and Fellows of Harvard College
    Inventors: Eric N. Jacobsen, James L. Leighton, Luis E. Martinez