Patents by Inventor Luis Fernando Romero Millán

Luis Fernando Romero Millán has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11931385
    Abstract: A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-?-d-xylanase) and a ?-glucanase (and optionally a further fibre degrading enzyme).
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: March 19, 2024
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Mai Faurschou Isaksen, Marion Bernardeau, Luis Fernando Romero Millan, Elijah G. Kiarie, Susan Lund Arent, Päivi Nurminen, Sofia Forssten, Daniel Petri, Elizabeth Ann Galbraith, Mari Ellen Davis
  • Publication number: 20230093634
    Abstract: The present invention relates to a method for solubilising arabinoxylan-containing material (particularly insoluble arabinoxylan-containing material), comprising admixing a xylan-containing material with a xylanase comprising a polypeptide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10. SEQ ID No. 11 or SEQ ID No. 15, or a variant, homologue, fragment or derivative thereof having at least 75% identity with SEQ ID No. 3 or SEQ ID No. 2 or SEQ ID No. 1 or SEQ ID No. 9 or SEQ ID No. 10 or SEQ ID No. 11 or SEQ ID No. 15; or a polypeptide sequence which comprises SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10. SEQ ID No. 11 or SEQ ID No. 15 with a conservative substitution of at least one of the amino acids; or a xylanase which is encoded by a nucleotide sequence shown herein as SEQ ID No. 6, SEQ ID No. 5, SEQ ID No. 4, SEQ ID No. 12. SEQ ID No. 13. SEQ ID No. 14. SEQ ID No. 16. SEQ ID No. 17 or SEQ ID No.
    Type: Application
    Filed: September 1, 2022
    Publication date: March 23, 2023
    Inventors: Luis Fernando Romero Millan, Susan Arent Lund, Brian Soegaard Laursen, Elijah Gituanjah Kiarie, Zhenghong Zhang, Rosalyn Lau, Zheyong Yu, Floor Klaaske Kooy, Jan Hendrik Van Tuijl, Bart Christiaan Koops, Mads Brogger Pedersen, Soren Dalsgaard
  • Publication number: 20220218001
    Abstract: Novel superoxide dismutases of fungal origin are active, gastric stable and thermal stable, and effective for use in animal feed additives. The use of superoxide dismutase in animal feed improve animal growth, animal health and intestinal health of animals.
    Type: Application
    Filed: April 5, 2020
    Publication date: July 14, 2022
    Applicant: Novozymes A/S
    Inventors: Ming Li, Marianne Thorup Cohn, Kirk Matthew Schnorr, Elodie Bacou, Luis Fernando Romero Millan, Maria Walsch, Tianqi Sun, Ye Liu, Lan Tang, Estefania Perez Calvo, Peter Wagner
  • Publication number: 20220183322
    Abstract: Novel polypeptides of fungal origin with catalase active are active, gastric stable and thermal stable, and effective for use in animal feed additives.
    Type: Application
    Filed: April 5, 2020
    Publication date: June 16, 2022
    Applicant: Novozymes A/S
    Inventors: Ming Li, Kirk Matthew Schnorr, Ye Liu, Lan Tang, Elodie Bacou, Luis Fernando Romero Millan, Maria Walsch, Estefania Perez Calvo, Peter Wagner
  • Publication number: 20220040241
    Abstract: A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-?-d-xylanase) and a ?-glucanase (and optionally a further fibre degrading enzyme).
    Type: Application
    Filed: July 6, 2021
    Publication date: February 10, 2022
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Mai Faurschou Isaksen, Marion Bernardeau, Luis Fernando Romero Millan, Elijah G. Kiarie, Susan Arent Lund, Päivi Nurminen, Sofia Forssten, Daniel Petri, Elizabeth Ann Galbraith, Mari Ellen Davis
  • Patent number: 11172693
    Abstract: A feed additive composition comprising a direct fed microbial in combination with a protease, and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease and a phytase.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: November 16, 2021
    Assignee: DuPont Nutrition Biosciences APS
    Inventor: Luis Fernando Romero Millan
  • Publication number: 20200318092
    Abstract: The present invention relates to a method for solubilising arabinoxylan-containing material (particularly insoluble arabinoxylan-containing material), comprising admixing a xylan-containing material with a xylanase comprising a polypeptide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15, or a variant, homologue, fragment or derivative thereof having at least 75% identity with SEQ ID No. 3 or SEQ ID No. 2 or SEQ ID No. 1 or SEQ ID No. 9 or SEQ ID No. 10 or SEQ ID No. 11 or SEQ ID No. 15; or a polypeptide sequence which comprises SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15 with a conservative substitution of at least one of the amino acids; or a xylanase which is encoded by a nucleotide sequence shown herein as SEQ ID No. 6, SEQ ID No. 5, SEQ ID No. 4, SEQ ID No. 12, SEQ ID No. 13, SEQ ID No. 14, SEQ ID No. 16, SEQ ID No.17 or SEQ ID No.
    Type: Application
    Filed: April 3, 2020
    Publication date: October 8, 2020
    Inventors: LUIS FERNANDO ROMERO MILLAN, SUSAN ARENT LUND, BRIAN SOEGAARD LAURSEN, ELIJAH G. KIARIE, ZHENGHONG ZHANG, ROSALYN LAU, ZHEYONG YU, FLOOR K KOOY, JAN HENDRIK A VAN TUIJL, BART C KOOPS, MADS BROEGGER PEDERSEN, SOREN DALSGAARD
  • Publication number: 20200281225
    Abstract: Disclosed is feed additive composition consisting essentially of a direct fed microbial comprising one or more bacterial strains in combination with at least one protease and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed, which method comprising administering to a subject a direct fed microbial in combination with a protease.
    Type: Application
    Filed: November 4, 2016
    Publication date: September 10, 2020
    Inventors: Elijah G. Kiarie, Luis Fernando Romero Millan, Laura Payling, Maria Walsh, Susan Arent Lund
  • Publication number: 20200245642
    Abstract: A method of preparing a feed additive composition comprising: (a) admixing at least one proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having (i) (A) Proline at P1; and (B) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids at P1; or (ii) (a?) Proline at PV; and (b?) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids or amines at PV; and one or more ingredients selected from the group consisting of a salt, polyol including sorbitol and glycerol, whe
    Type: Application
    Filed: January 16, 2020
    Publication date: August 6, 2020
    Inventors: SVEND HAANING, KARSTEN MATTHIAS KRAGH, STEPAN SHIPOVSKOV, ANDREI MIASNIKOV, MARIA MA, LUIS FERNANDO ROMERO MILLAN, LUKE BARNARD, SHUKUN YU, ERNST MEINJOHANNS, STEFFEN YDE BAK, PÄIVI NURMINEN, HELI ANGLENIUS
  • Patent number: 10695384
    Abstract: A feed additive composition comprising a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for avoiding the negative effects of necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: June 30, 2020
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Luis Fernando Romero Millan, Gregory Ross Siragusa, Mari Ellen Davis, Alexandra Helena Smith
  • Patent number: 10612014
    Abstract: The present invention relates to a method for solubilizing arabinoxylan-containing material (particularly insoluble arabinoxylan-containing material), comprising admixing a xylan-containing material with a xylanase comprising a polypeptide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15, or a variant, homolog, fragment or derivative thereof having at least 75% identity with SEQ ID No. 3 or SEQ ID No. 2 or SEQ ID No. 1 or SEQ ID No. 9 or SEQ ID No. 10 or SEQ ID No. 11 or SEQ ID No. 15; or a polypeptide sequence which comprises SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15 with a conservative substitution of at least one of the amino acids; or a xylanase which is encoded by a nucleotide sequence shown herein as SEQ ID No. 6, SEQ ID No. 5, SEQ ID No. 4, SEQ ID No. 12, SEQ ID No. 13, SEQ ID No. 14, SEQ ID No. 16, SEQ ID No. 17 or SEQ ID No.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: April 7, 2020
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Luis Fernando Romero Millan, Susan Arent Lund, Brian Soegaard Laursen, Elijah G Kiarie, Zhenghong Zhang, Rosalyn Lau, Zheyong Yu, Floor K Kooy, Jan Hendrik A Van Tuijl, Bart C Koops, Mads Broegger Pedersen, Soeren Dalsgaard
  • Publication number: 20190223470
    Abstract: A feed additive composition comprising a direct fed microbial in combination with a protease, and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease and a phytase.
    Type: Application
    Filed: January 25, 2019
    Publication date: July 25, 2019
    Inventor: Luis Fernando Romero Millan
  • Publication number: 20190090525
    Abstract: The present invention relates to a method of preparing a corn based product said method comprising contacting a plant composition comprising (consisting of or consisting essentially of) corn or a corn by-product or a combination thereof with a xylanase comprising: i) a polypeptide as set forth in SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or ii) a variant, fragment homologue, fragment or derivative thereof having at least 85% identity with SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or with a xylanase encoded by: a) a nucleotide sequence shown herein as SEQ ID No. 3. SEQ ID No. 2 or SEQ ID No. 1; or b) a nucleotide sequence which can hybridize to the complement of SEQ ID No. 3. SEQ ID No. 2 or SEQ ID No. 1 under high stringency conditions: or c) a nucleotide sequence which has at least 80% identity with SEQ ID No. 3. SEQ ID No. 2 or SEQ ID No. 1. The present invention further relates to the use of the enzyme to produce corn based feedstuffs.
    Type: Application
    Filed: October 10, 2018
    Publication date: March 28, 2019
    Inventors: Susan Arent Lund, Brian Soegaard Laursen, Elijah G. Kiarie, Luis Fernando Romero Millan, Zhenghong Zhang, Rosalyn Lau, Zheyong Yu, Mads Broegger Pedersen, Soeren Dalsgaard
  • Patent number: 10227623
    Abstract: A process for mechanical destructuring of cellulosic biomass was developed that makes use of a short application of high compression, impact, and shearing forces. The biomass may be destructured using a specific energy input that is less than 40% of the total combustible energy of the biomass. The destructured biomass, with or without saccharification and/or in-feed glycosyl hydrolase enzymes, may be used in feed applications.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: March 12, 2019
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Wathudura Indika Namal De Silva, Paul Joseph Fagan, F Glenn Gallagher, Zheng-Zheng Huang, Guangliang Gary Liu, Aaron Perelman, Luis Fernando Romero Millan, Anton Shpilsky, Daniel A Slanac, Maria Walsh
  • Publication number: 20180295858
    Abstract: A method of preparing a feed additive composition comprising: (a) admixing at least one proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having (i) (A) Proline at P1; and (B) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids at P1; or (ii) (a?) Proline at P1?; and (b?) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids or amines at P1?; and one or more ingredients selected from the group consisting of a salt, polyol including sorbitol and glycerol, w
    Type: Application
    Filed: October 23, 2015
    Publication date: October 18, 2018
    Inventors: Svend Haaning, Karsten Matthias Kragh, Stepan Shipovskov, Andrei Miasnikov, Maria Ma, Luis Fernando Romero Millan, Luke Barnard, Shukun Yu, Ernst Meinjohanns, Steffen Bak, Päivi Nurminen, Heli Putaala
  • Patent number: 10058110
    Abstract: The disclosure relates to enzyme producing Bacillus strains that provide benefits to animals and methods of using these strains. In one embodiment, the disclosure relates compositions comprising the enzyme producing Bacillus strains. In yet another embodiment, the disclosure relates to a feed for an animal comprising enzyme producing Bacillus strains.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: August 28, 2018
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Mari Ellen Davis, Justin Sawall, Anthony Neumann, Gregory Ross Siragusa, Luis Fernando Romero Millan
  • Publication number: 20180094253
    Abstract: The present invention relates to a method for solubilising arabinoxylan-containing material (particularly insoluble arabinoxylan-containing material), comprising admixing a xylan-containing material with a xylanase comprising a polypeptide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15, or a variant, homologue, fragment or derivative thereof having at least 75% identity with SEQ ID No. 3 or SEQ ID No. 2 or SEQ ID No. 1 or SEQ ID No. 9 or SEQ ID No. 10 or SEQ ID No. 11 or SEQ ID No. 15; or a polypeptide sequence which comprises SEQ ID No. 3. SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15 with a conservative substitution of at least one of the amino acids; or a xylanase which is encoded by a nucleotide sequence shown herein as SEQ ID No. 6, SEQ ID No. 5, SEQ ID No. 4, SEQ ID No. 12, SEQ ID No. 13, SEQ ID No. 14, SEQ ID No. 16, SEQ ID No. 17 or SEQ ID No.
    Type: Application
    Filed: December 15, 2017
    Publication date: April 5, 2018
    Inventors: LUIS FERNANDO ROMERO MILLAN, SUSAN ARENT LUND, BRIAN SOEGAARD LAURSEN, ELIJAH G. KIARIE, ZHENGHONG ZHANG, ROSALYN LAU, ZHEYONG YU, FLOOR K KOOY, JAN HENDRIK A VAN TUIJL, BART C KOOPS, MADS BROEGGER PEDERSEN, SOEREN DALSGAARD
  • Publication number: 20150351433
    Abstract: The present invention provides a xylanase comprising amino acid sequence as set forth in SEQ ID No.1, SEQ ID No.2 or SEQ ID No.8, and a nucleotide sequence encoding said xylanase shown as SEQ ID No.3, SEQ ID No.4 or SEQ ID No.5. The present invention also provides a method of preparing a corn based product comprising contacting a plant composition comprising corn or a corn by-product or a combination thereof with said xylanase.
    Type: Application
    Filed: August 3, 2012
    Publication date: December 10, 2015
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Susan Lund Arent, Brian Sogaard Laursen, Elijah Gituanjah Kiarie, Luis Fernando Romero Millan, Zhenghong Zhang, Rosalyn Lau, Zheyong Yu, Soren Dalsgaard
  • Publication number: 20150216203
    Abstract: A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-?-d-xylanase) and a ?-glucanase (and optionally a further fibre degrading enzyme), wherein the DFM is selected from the group consisting of an enzyme producing strain; a C5 sugar-fermenting strain; a short-chain fatty acid-producing strain; a fibrolytic, endogenous microflora-promoting strain; or combinations thereof. The DFM may be selected from the group consisting of: Bacillus subtilis AGTP BS3BP5, Bacillus subtilis AGTP BS442, B. subtilis AGTP BS521, B. subtilis AGTP BS918, Bacillus subtilis AGTP BS1013, B. subtilis AGTP BS1069, B. subtilis AGTP 944, B. pumilus AGTP BS 1068 or B.
    Type: Application
    Filed: August 2, 2013
    Publication date: August 6, 2015
    Applicant: DUPONT NUTRITIONAL BIOSCIENCES APS
    Inventors: Mai Faurschou Isaksen, Marion Bernardeau, Luis Fernando Romero Millan, Elijah Gituanjah Kiarie, Susan Lund Arent, Piiivi Helena Nurminen, Sofia Forssten, Daniel Petri, Elizabeth Ann Galbraith
  • Publication number: 20150210993
    Abstract: The present invention relates to a method for solubilising arabinoxylan-containing material (particularly insoluble arabinoxylan-containing material), comprising admixing a xylan-containing material with a xylanase comprising a polypeptide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15, or a variant, homologue, fragment or derivative thereof having at least 75% identity with SEQ ID No. 3 or SEQ ID No. 2 or SEQ ID No. 1 or SEQ ID No. 9 or SEQ ID No. 10 or SEQ ID No. 11 or SEQ ID No. 15; or a polypeptide sequence which comprises SEQ ID No. 3, SEQ ID No. 2, SEQ ID No. 1, SEQ ID No. 9, SEQ ID No. 10, SEQ ID No. 11 or SEQ ID No. 15 with a conservative substitution of at least one of the amino acids; or a xylanase which is encoded by a nucleotide sequence shown herein as SEQ ID No. 6, SEQ ID No. 5, SEQ ID No. 4, SEQ ID No. 12, SEQ ID No. 13, SEQ ID No. 14, SEQ ID No. 16, SEQ ID No. 17 or SEQ ID No.
    Type: Application
    Filed: August 2, 2013
    Publication date: July 30, 2015
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Susan Lund Arent, Brian Sogaard Laursen, Elijah Gituanjah Kiarie, Luis Fernando Romero Millan, Zhenghong Zhang, Rosalyn Lau, Zheyong Yu, Floor Klaaske Kooy, Jan Hendrik Van Tuijl, Bart Christiaan Koops, Mads Brogger Pedersen, Soren Dalsgaard