Patents by Inventor Luis Gerardo Hernandez Aguayo

Luis Gerardo Hernandez Aguayo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Real time electrophysiological testing of agents of interest for treatment of amyloid-type diseases
    Patent number: 8609361
    Abstract: This invention corresponds to an in vitro method that employs an electrophysiology technique; in particular, an embodiment of the patch-clamp technique in its perforated type, which will allow us evaluating the neurotoxic capacity of protein structures associated to the generation of neurodegenerative diseases. It addition, it allows evaluating potential pharmacologic capacities of candidate molecules (drugs) in order to prevent, treat, or cure the said diseases. The invention involves the use of peptides that cause neurodegenerative diseases in order to form a spontaneous perforated recording that only occurs with peptides in the patch clamp glass pipette.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: December 17, 2013
    Assignee: Universidad de Concepcion
    Inventors: Luis Gerardo Hernandez Aguayo, Carlos Roberto Martinez Opazo, Jorge Luis Rivera Parodi
  • Electrophysiology Methods for Identification of Protein Structures in Membranes Associated to Neurodegenerative Diseases
    Publication number: 20100311102
    Abstract: This invention corresponds to an in vitro method that employs an electrophysiology technique; in particular, an embodiment of the patch-clamp technique in its perforated type, which will allow us evaluating the neurotoxic capacity of protein structures associated to the generation of neurodegenerative diseases. It addition, it allows evaluating potential pharmacologic capacities of candidate molecules (drugs) in order to prevent, treat, or cure the said diseases. The invention involves the use of peptides that cause neurodegenerative diseases in order to form a spontaneous perforated recording that only occurs with peptides in the patch clamp glass pipette.
    Type: Application
    Filed: October 9, 2008
    Publication date: December 9, 2010
    Applicant: UNIVERSIDAD DE CONCEPCION
    Inventors: Luis Gerardo Hernandez Aguayo, Carlos Roberto Martinez Opazo, Jorge Luis Rivera Parodi