Patents by Inventor Luis Ghira BORGES

Luis Ghira BORGES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric antigen receptor system with adaptable receptor specificity
    Patent number: 11883432
    Abstract: The present disclosure provides chimeric antigen receptors (CARs), particularly CARs that have adaptable receptor specificity (arCARs). Also provided are polypeptides of the CARs and other related molecules, polynucleotides, vectors, and cell compositions comprising the same. Pharmaceutical compositions comprising the polypeptides, polynucleotides, vectors, or cells of the present disclosure, and their uses in treating a disease in a subject are also provided.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: January 30, 2024
    Assignee: CENTURY THERAPEUTICS, INC.
    Inventors: Jill Marinari Carton, Michael Francis Naso, Luis Ghira Borges, John Wheeler, Andrew Devaney
  • GENE TRANSFER VECTORS AND METHODS OF ENGINEERING CELLS
    Publication number: 20220331361
    Abstract: The present disclosure provides compositions and methods for use in genome engineering of induced pluripotent stem cells (iPSCs). Specifically, the methods and compositions described are useful for introducing transgenes into iPSCs such as pluripotent hematopoietic stem cells and/or progenitor cells (HSC/PC) using an CRISPR nuclease-based system (e.g., MAD7 nuclease-based system) and preparing immune-effector cells derived from the iPSCs.
    Type: Application
    Filed: April 6, 2022
    Publication date: October 20, 2022
    Applicant: CENTURY THERAPEUTICS, INC.
    Inventors: Michael Francis NASO, Buddha GURUNG, Jill Marinari CARTON, John WHEELER, Luis Ghira BORGES
  • CHIMERIC ANTIGEN RECEPTOR SYSTEM WITH ADAPTABLE RECEPTOR SPECIFICITY
    Publication number: 20220193133
    Abstract: The present disclosure provides chimeric antigen receptors (CARs), particularly CARs that have adaptable receptor specificity (arCARs). Also provided are polypeptides of the CARs and other related molecules, polynucleotides, vectors, and cell compositions comprising the same. Pharmaceutical compositions comprising the polypeptides, polynucleotides, vectors, or cells of the present disclosure, and their uses in treating a disease in a subject are also provided.
    Type: Application
    Filed: December 17, 2021
    Publication date: June 23, 2022
    Applicant: CENTURY THERAPEUTICS, INC.
    Inventors: Jill Marinari CARTON, Michael Francis NASO, Luis Ghira BORGES, John WHEELER, Andrew DEVANEY