Abstract: The present invention relates to a protein subunit vaccine comprising at least one antigen characterized in that it comprises at least one monomer from at least one variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), wherein the at least one monomer is selected from the group consisting of the S1 subunit of the Spike protein or the receptor-binding domain (RBD) of the Spike protein. In an aspect of the present invention, the protein subunit vaccine comprises at least one antigen characterized in that it comprises two monomers from at least one variant of SARS-CoV-2, wherein each of the monomers are selected from the group consisting of the S1 subunit or RBD protein, and wherein the monomers are chemically bound to each other, optionally through a linker, forming fusion dimers or non-fusion dimers. The protein subunit vaccine may further comprise at least an adjuvant and at least an immunostimulant.

Abstract: The invention relates to an immunogenic or vaccine composition comprising an inactivated bacterium from the species Brachyspira hyodysenteriae, to a method for producing said composition and to the medical use of this composition for inducing an immune response against a bacterium from the species Brachyspira hyodysenteriae or for protecting against an infection caused by a bacterium from the species Brachyspira hyodysenteriae. Further, the invention relates to a method for selecting a bacterium from the species Brachyspira hyodysenteriae useful for manufacturing a vaccine against swine dysentery.

Abstract: The present invention relates to mutant strains of Mycoplasma hyopneumoniae and to a method for preparing them. It also relates to carrier vectors which are used in said method, to vaccine compositions and to vaccination kits comprising the compositions against porcine enzootic pneumonia and other swine diseases. It also relates to the use of M. hyopneumoniae as a host for expressing recombinant proteins and other DNA sequences of interest.

Abstract: The present invention is related to a biocide formulation to protect, prevent or treat skin infections in a combination of pentahydrate copper salts and heptahydrate zinc salts as active biocide compounds. Preferably, the copper salt is pentahydrate copper salt and the zinc salt is heptahydrate zinc salt. In a preferred realization, the formulation comprises agents to enhance adhesion to the skin. In another preferred realization of the invention, the formulation is suitable to be applied to the teats or udders of the milking animals, inter milking, for the treatment and prevention of mastitis.

Abstract: The present invention is related to a biocide formulation to protect, prevent or treat skin infections in a combination of pentahydrate copper salts and heptahydrate zinc salts as active biocide compounds. Preferably, the copper salt is pentahydrate copper salt and the zinc salt is heptahydrate zinc salt. In a preferred realization, the formulation comprises agents to enhance adhesion to the skin. In another preferred realization of the invention, the formulation is suitable to be applied to the teats or udders of the milking animals, inter milking, for the treatment and prevention of mastitis.

Abstract: The present invention relates to mutant strains of Mycoplasma hyopneumoniae and to a method for preparing them. It also relates to carrier vectors which are used in said method, to vaccine compositions and to vaccination kits comprising the compositions against porcine enzootic pneumonia and other swine diseases. It also relates to the use of M. hyopneumoniae as a host for expressing recombinant proteins and other DNA sequences of interest.