Patents by Inventor Luis Leon
Luis Leon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11987841Abstract: Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.Type: GrantFiled: October 9, 2018Date of Patent: May 21, 2024Assignee: Psomagen, Inc.Inventors: Zachary Apte, Jessica Richman, Daniel Almonacid, Eduardo Morales, Luis Leon, Sara W. Bird, Juan Ugalde
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Patent number: 11445843Abstract: An improved mechanical shoehorn that provides a new and unique enhanced application. The shoehorn includes a pivotable handle with a substantial length which helps to push the heel into the shoe. Additionally, the shoehorn includes an arched frontal assembly that widens the shoe opening which makes it easier for a user to slide their foot into the shoe. In one embodiment, the shoehorn further comprises a sock applicator that attaches to the back of the main device.Type: GrantFiled: May 12, 2020Date of Patent: September 20, 2022Inventor: Pedro Luis Leon
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Patent number: 11345355Abstract: The present invention is a method for determining an optimal speed of a first vehicle preceded by a second vehicle. Position, speed and acceleration of the second vehicle are measured in order to determine a trajectory thereof, and a dynamic model of the first vehicle is constructed. The optimal speed is then determined by minimizing the energy consumption of the vehicle by use of the dynamic model by minimization being constrained by the trajectory of the second vehicle.Type: GrantFiled: September 6, 2018Date of Patent: May 31, 2022Assignee: IFP ENERGIES NOUVELLESInventors: Luis Leon Ojeda, Jihun Han, Antonio Sciarretta, Laurent Thibault, Giovanni De Nunzio
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Publication number: 20210353084Abstract: An improved mechanical shoehorn that provides a new and unique enhanced application. The shoehorn includes a pivotable handle with a substantial length which helps to push the heel into the shoe. Additionally, the shoehorn includes an arched frontal assembly that widens the shoe opening which makes it easier for a user to slide their foot into the shoe. In one embodiment, the shoehorn further comprises a sock applicator that attaches to the back of the main device.Type: ApplicationFiled: May 12, 2020Publication date: November 18, 2021Inventor: Pedro Luis Leon
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Patent number: 10968497Abstract: A structure is heated in a tool. The structure is quenched in the tool such that a shape of the structure is maintained, in which quenching is performed by contacting the structure with a quenching medium.Type: GrantFiled: December 14, 2017Date of Patent: April 6, 2021Assignee: The Boeing CompanyInventors: Marc R. Matsen, Lee Charles Firth, Luis Leon
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Patent number: 10828615Abstract: The photoreactor comprises at least one housing (11) for at least one reaction vessel and at least one light source for lighting said at least one reaction vessel, and the photoreactor comprises: a first module (1) provided with said at least one housing (11) for at least one reaction vessel and comprising a cooling/heating circuit (15) for regulating the temperature of said at least one reaction vessel; a second module (2) provided with said at least one light source; and a thermal insulating layer (5) placed between the first module (1) and the second module (2). It improves reproducibility of the reactions by temperature and light intensity control.Type: GrantFiled: May 30, 2018Date of Patent: November 10, 2020Assignees: FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ), INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS (ICREA)Inventors: Julio Lloret-Fillol, Carla Casadevall Serrano, José Luis León, Arnau Call Quintana, Alicia Casitas Montero, Joan Jose Pla, Javier Pérez Hernández, Francesc Xavier Caldentey Frontera
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Publication number: 20200299763Abstract: Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.Type: ApplicationFiled: October 9, 2018Publication date: September 24, 2020Inventors: Zachary Apte, Jessica Richman, Daniel Almonacid, Eduardo Morales, Luis Leon, Sara W. Bird, Juan Ugalde
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Patent number: 10766626Abstract: Methods are disclosed for forming metal workpieces made from a heat-treatable metal that has been shaped and tempered according to specified protocols that facilitate formation of large contoured unitary metal structures having welds that are retained in the finished structure, and finished metal structures made according to such methods.Type: GrantFiled: May 24, 2017Date of Patent: September 8, 2020Assignee: The Boeing CompanyInventors: Luis Leon, Michael Nill, Pradip K. Saha, Carol S. Oliver, Ricole A. Johnson
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Publication number: 20200263171Abstract: Embodiments of a method and/or system, such as for preparation of a normalized library for sequencing such as next-generation sequencing, can include one or more of: generating one or more normalized amplicon libraries; generating one or more normalized microbial community-associated libraries; and/or generating one or more normalized combined sequence libraries associated with amplicon-associated sequencing and microbial community-associated sequencing.Type: ApplicationFiled: September 7, 2018Publication date: August 20, 2020Inventors: Zachary Apte, Jessica Richman, Daniel Almonacid, Eduardo Morales, Rodrigo Ortiz, Nicolas Ordenes, Juan Jimenez, Cristian Bravo, Natalia Scioscia, Eduardo Olivares, Luis Leon, Paulo Covarrubias, Felipe Sepulveda, Felipe Melis
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Publication number: 20200179896Abstract: The photoreactor comprises at least one housing (11) for at least one reaction vessel and at least one light source for lighting said at least one reaction vessel, and the photoreactor comprises: a first module (1) provided with said at least one housing (11) for at least one reaction vessel and comprising a cooling/heating circuit (15) for regulating the temperature of said at least one reaction vessel; a second module (2) provided with said at least one light source; and a thermal insulating layer (5) placed between the first module (1) and the second module (2). It improves reproducibility of the reactions by temperature and light intensity control.Type: ApplicationFiled: May 30, 2018Publication date: June 11, 2020Applicants: FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ), INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS (ICREA)Inventors: Julio LLORET-FILLOL, Carla CASADEVALL SERRANO, José Luis LEÓN, Arnau CALL QUINTANA, Alicia CASITAS MONTERO, Joan Jose PLA, Javier PÉREZ HERNÁNDEZ, Francesc Xavier CALDENTEY FRONTERA
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Publication number: 20200123539Abstract: Embodiments of a method 100 and/or system 200 or library preparation for sequencing associated with microorganisms can include: preparing a set of unique molecular identifier (UMI)-based molecules associated with one or more targets; preparing a set of sequencing-based primers; generating a set of tagged target molecules based on the set of UMI-based molecules and one or more samples associated with the one or more targets; and/or generating a set of sequencing-ready tagged target molecules based on the tagged target molecules and the set of sequencing-based primers.Type: ApplicationFiled: June 20, 2018Publication date: April 23, 2020Inventors: Zachary APTE, Jessica RICHMAN, Daniel AL-MONACID, Juan JIMINEZ, Rodrigo ORTIZ, Eduardo MORALES, Paulo COVARRUBIAS, Eduardo OLIVARES, Nicolas ORDENES, Luis LEON
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Publication number: 20190185949Abstract: A structure is heated in a tool. The structure is quenched in the tool such that a shape of the structure is maintained, in which quenching is performed by contacting the structure with a quenching medium.Type: ApplicationFiled: December 14, 2017Publication date: June 20, 2019Inventors: Marc R. Matsen, Lee Charles Firth, Luis Leon
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Publication number: 20190136310Abstract: Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.Type: ApplicationFiled: October 9, 2018Publication date: May 9, 2019Inventors: Zachary Apte, Jessica Richman, Daniel Almonacid, Eduardo Morales, Luis Leon, Sara W. Bird, Juan Ugalde
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Publication number: 20190078085Abstract: Embodiments of a method and/or system, such as for preparation of a normalized library for sequencing such as next-generation sequencing, can include one or more of: generating one or more normalized amplicon libraries; generating one or more normalized microbial community-associated libraries; and/or generating one or more normalized combined sequence libraries associated with amplicon-associated sequencing and microbial community-associated sequencing.Type: ApplicationFiled: September 7, 2018Publication date: March 14, 2019Inventors: Zachary Apte, Jessica Richman, Daniel Almonacid, Eduardo Morales, Rodrigo Ortiz, Nicolas Ordenes, Juan Jimenez, Cristian Bravo, Natalia Scioscia, Eduardo Olivares, Luis Leon, Paulo Covarrubias, Felipe Sepulveda, Felipe Melis
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Publication number: 20190071096Abstract: The present invention relates to a method for determining an optimal speed to be reached for a first vehicle preceded by a second vehicle. For this method, the position, the speed and the acceleration of the second vehicle are measured (MES) in order to determine the trajectory thereof (POS), and a dynamic model (MOD) of the first vehicle is constructed. The speed to be reached (VIT) is then determined by minimizing (MIN) the energy consumption of the vehicle by means of the dynamic model (MOD), the minimization being constrained by the trajectory (POS) of the second vehicle.Type: ApplicationFiled: September 6, 2018Publication date: March 7, 2019Inventors: Luis LEON OJEDA, Jihun HAN, Antonio SCIARRETTA, Laurent THIBAULT, Giovanni DE NUNZIO
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Publication number: 20180362967Abstract: Embodiments of a method 100 and/or system 200 or library preparation for sequencing associated with microorganisms can include: preparing a set of unique molecular identifier (UMI)-based molecules associated with one or more targets; preparing a set of sequencing-based primers; generating a set of tagged target molecules based on the set of UMI-based molecules and one or more samples associated with the one or more targets; and/or generating a set of sequencing-ready tagged target molecules based on the tagged target molecules and the set of sequencing-based primers.Type: ApplicationFiled: June 20, 2018Publication date: December 20, 2018Inventors: Zachary Apte, Jessica Richman, Daniel Almonacid, Juan Jimenez, Rodrigo Ortiz, Eduardo Morales, Paulo Covarrubias, Eduardo Olivares, Nicolas Ordenes, Luis Leon
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Publication number: 20180339783Abstract: Methods are disclosed for forming metal workpieces made from a heat-treatable metal that has been shaped and tempered according to specified protocols that facilitate formation of large contoured unitary metal structures having welds that are retained in the finished structure, and finished metal structures made according to such methods.Type: ApplicationFiled: May 24, 2017Publication date: November 29, 2018Inventors: Luis Leon, Michael Nill, Pradip K. Saha, Carol S. Oliver, Ricole A. Johnson
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Patent number: 8329312Abstract: A superplastically formed structural assembly is provided, as is an associated preform and method for forming such an assembly. The assembly includes a skin member and a support member that are joined to define a space between the members and between the joints. The assembly can be produced by joining the members in a flat configuration, and then forming the resulting preform to a predetermined shape of the structural assembly. The support member defines at least one aperture in communication with the space between the members. Thus, the skin member can be formed by delivering a pressurized fluid through the support member to the skin member, e.g., to superplastically form the skin member against a die that defines a contour surface corresponding in shape to the predetermined configuration of the assembly. The support member can extend in a substantially direct configuration between opposing portions of the skin member.Type: GrantFiled: June 27, 2011Date of Patent: December 11, 2012Assignee: The Boeing CompanyInventors: Daniel G. Sanders, David W. Foutch, Jeff D. Will, Luis Leon, Gregory L. Ramsey, Garry A. Booker
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Publication number: 20110256343Abstract: A superplastically formed structural assembly is provided, as is an associated preform and method for forming such an assembly. The assembly includes a skin member and a support member that are joined to define a space between the members and between the joints. The assembly can be produced by joining the members in a flat configuration, and then forming the resulting preform to a predetermined shape of the structural assembly. The support member defines at least one aperture in communication with the space between the members. Thus, the skin member can be formed by delivering a pressurized fluid through the support member to the skin member, e.g., to superplastically form the skin member against a die that defines a contour surface corresponding in shape to the predetermined configuration of the assembly. The support member can extend in a substantially direct configuration between opposing portions of the skin member.Type: ApplicationFiled: June 27, 2011Publication date: October 20, 2011Applicant: The Boeing CompanyInventors: Daniel G. Sanders, David W. Foutch, Jeff D. Will, Luis Leon, Gregory L. Ramsey, Garry A. Booker
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Patent number: 7967240Abstract: A superplastically formed structural assembly is provided, as is an associated preform and method for forming such an assembly. The assembly includes a skin member and a support member that are joined to define a space between the members and between the joints. The assembly can be produced by joining the members in a flat configuration, and then forming the resulting preform to a predetermined shape of the structural assembly. The support member defines at least one aperture in communication with the space between the members. Thus, the skin member can be formed by delivering a pressurized fluid through the support member to the skin member, e.g., to superplastically form the skin member against a die that defines a contour surface corresponding in shape to the predetermined configuration of the assembly. The support member can extend in a substantially direct configuration between opposing portions of the skin member.Type: GrantFiled: March 16, 2007Date of Patent: June 28, 2011Assignee: The Boeing CompanyInventors: Daniel G. Sanders, David W. Foutch, Jeff D. Will, Luis Leon, Gregory L. Ramsey, Garry A. Booker