Patents by Inventor Luis M Negron

Luis M Negron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Supramolecular hacky sacks (SHS), method of synthesis and applications thereof
    Patent number: 10106572
    Abstract: The invention is directed to small molecules that self-assemble hierarchically to form NPs termed SHS (due to their architectural features). These SHS are composed by precise supramolecules known as Supramolecular G-Quadruplexes (SGQs) which are formed when amphiphilic guanosine (G) derivatives that self-assemble in presence of salt by non-covalent interactions. The resulting SGQs are made of amphiphilic guanosine (G) subunits (with precisely eight subunits at neutral pH (pH>5.7) or sixteen subunits at acidic pH (pH<5.7)). The SGQs are responsive entities that further self-assemble upon an external stimulus, such as an increase in temperature or a change in pH, leading to the formation of the aforementioned SHS.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: October 23, 2018
    Assignee: University of Puerto Rico
    Inventors: Jose M Rivera, Luis M Negron