Patents by Inventor Luis-Manuel Vaz

Luis-Manuel Vaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing dibenzothiazepine compounds
    Patent number: 7671195
    Abstract: A dibenzothiazepine compound is suitably prepared by subjecting a 2-amino-2?-carboxy-diphenylsulfide compound to dehydration-condensation reaction in the presence of an acidic catalyst; the 2-amino-2?-carboxy-diphenylsulfide compound is suitably prepared by reducing a 2-nitro-2?-carboxy-diphenylsulfide compound in a lower aliphatic ester solvent; and the 2-nitro-2?-carboxy-diphenylsulfide compound is suitably prepared by reacting a nitrobenzene compound with a thiosalicylic acid compound in a mixture of a lower aliphatic alcohol and water.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: March 2, 2010
    Assignees: AstraZeneca UK Limited, UBE Industries, Ltd.
    Inventors: Paul Michael Murray, Luis-Manuel Vaz, Debra Ainge, Katsumasa Harada, Shigeyoshi Nishino, Kiyotaka Yoshii
  • Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl
    Publication number: 20100041905
    Abstract: The present invention relates to a novel process for the preparation of compounds of formula (V) wherein X, Q, R1, R1a and R2 are as defined in the specification, the compounds being useful in the preparation of therapeutic agents.
    Type: Application
    Filed: July 17, 2007
    Publication date: February 18, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Debra Ainge, Philip Cornwall, Duncan Michael Gill, Luis Manuel Vaz
  • Novel Crystal Modifications
    Publication number: 20090221640
    Abstract: Novel crystal modifications of (5S)-5-[4-(5-chloro-pyridin-2-yloxy)-piperidine-1-sulfonylmethyl]-5-methyl-imidazolidine-2,4-dione are disclosed together with processes for preparing such modifications, pharmaceutical compositions comprising such a modification, and the use of such a modification in therapy.
    Type: Application
    Filed: March 15, 2007
    Publication date: September 3, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Lars-Erik Briggner, Anders Eriksson, Neil Barnwell, Andrea Cole, Jacob Perkins, Luis-Manuel Vaz, Andrew Wells
  • Novel Process 1
    Publication number: 20080064884
    Abstract: The present invention relates to a novel process for the preparation of compounds of formula (I) wherein X, Q, R1 and R2 are as defined in the specification, the compounds being useful in the preparation of therapeutic agents. The invention further relates to novel intermediates useful in the preparation of the therapeutic agents.
    Type: Application
    Filed: May 3, 2007
    Publication date: March 13, 2008
    Applicant: AstraZeneca AB
    Inventors: Debra Ainge, Philip Cornwall, Duncan Michael Gill, Vinod Kumar, Luis Manuel Vaz, Philip O'Keefe, Rhona Sinclair, Edward Laurence Way
  • Process for preparing dibenzothiazepine compounds
    Publication number: 20070203336
    Abstract: A dibenzothiazepine compound is suitably prepared by subjecting a 2-amino-2?-carboxy-diphenylsulfide compound to dehydration-condensation reaction in the presence of an acidic catalyst; the 2-amino-2?-carboxy-diphenylsulfide compound is suitably prepared by reducing a 2-nitro-2?-carboxy-diphenylsulfide compound in a lower aliphatic ester solvent; and the 2-nitro-2?-carboxy-diphenylsulfide compound is suitably prepared by reacting a nitrobenzene compound with a thiosalicylic acid compound in a mixture of a lower aliphatic alcohol and water.
    Type: Application
    Filed: February 21, 2007
    Publication date: August 30, 2007
    Inventors: Paul Murray, Luis-Manuel Vaz, Debra Ainge, Katsumasa Harada, Shigeyoshi Nishino, Kiyotaka Yoshii