Abstract: The present invention relates to a vector for use in the treatment of a polyglutamine repeat spinocerebellar ataxia, which vector comprises cholesterol 24-hydroxylase encoding nucleic acid.

Abstract: A new edible oil and fat filtering device, designed to extend the useful life of oils used in frying procedures, designed to extend the useful life of oils used in frying procedures, due to the fact that it has reduced dimensions, enabled to be immersed in the frying pan directly into the oil to be filtered, thus eliminating the time spent with the removal and transport of the hot oil, compared to traditional filtering methods, reducing the filtering time and making the process safer; and at the same time keeping the oil viscosity low and making it easier to pass through the filtering element.

Abstract: The present invention relates to a vector for use in the treatment of a polyglutamine repeat spinocerebellar ataxia, which vector comprises cholesterol 24-hydroxylase encoding nucleic acid.

Abstract: A method for optimization of electrical discharge machining process for eroding a workpiece by an electrode mounted in an electrical discharge machine tool, wherein a plurality of electrodes are required to form a plurality of cavities on the workpiece.

Abstract: Some embodiments of the present BOP control systems include a system controller configured to actuate a first BOP function by communicating one or more commands to one or more nodes of a functional pathway selected from one or more available functional pathways associated with the first BOP function, each node comprising an actuatable component configured to actuate in response to a command received from the system controller, each node having one or more sensors configured to capture a first data set corresponding to actuation of the component and a processor configured to analyze the first data set to determine a useful life remaining of the component and/or compare the first data set to a second data set corresponding to a simulation of actuation of the component.

Abstract: The seeding positioner device applied to agricultural planters comprising a structure consisted of a rotating seed pusher that directs the seeds to a labyrinth (14) moving in a opposite direction, allowing to control the seed release as the speed the assembly rotates, so that the discharge spacing will be commanded by a gears-driven compartment (22) which directs the seeds to a discharge tube (23), wherein the pneumatic system generates positive air pressure. Thus, the compressed air will push the seed against the soil in order to maintain the perfect line positioning and increasing the planting speed. The seeding positioner device can be driven by an electric motor, a pneumatic motor, a hydraulic motor, a cardan shaft, a pitch chain, or a twisting cable, according to the planter type. In addition, the device constructional shape prevents the seeds from being damaged and loses germination capacity when passing through the mechanism, allowing the equipment to be applied and adapted to work with any seed type.

Abstract: A subsea processor may be located near the seabed of a drilling site and used to coordinate operations of underwater drilling components. The subsea processor may be enclosed in a single interchangeable unit that fits a receptor on an underwater drilling component, such as a blow-out preventer (BOP). The subsea processor may issue commands to control the BOP and receive measurements from sensors located throughout the BOP. The subsea processor may relay information to the surface for recording or monitoring. The subsea processor may also be programmed with a model from which to base operation of the BOP, such as in emergency conditions.

Abstract: A subsea processor may be located near the seabed of a drilling site and used to coordinate operations of underwater drilling components. The subsea processor may be enclosed in a single interchangeable unit that fits a receptor on an underwater drilling component, such as a blow-out preventer (BOP). The subsea processor may issue commands to control the BOP and receive measurements from sensors located throughout the BOP. The subsea processor may relay information to the surface for recording or monitoring. The subsea processor may also be programmed with a model from which to base operation of the BOP, such as in emergency conditions.

Abstract: The present invention relates to a vector for use in the treatment of a polyglutamine repeat spinocerebellar ataxia, which vector comprises cholesterol 24-hydroxylase encoding nucleic acid.

Abstract: Some embodiments of the present BOP control systems include a system controller configured to actuate a first BOP function by communicating one or more commands to one or more nodes of a functional pathway selected from one or more available functional pathways associated with the first BOP function, each node comprising an actuatable component configured to actuate in response to a command received from the system controller, each node having one or more sensors configured to capture a first data set corresponding to actuation of the component and a processor configured to analyze the first data set to determine a useful life remaining of the component and/or compare the first data set to a second data set corresponding to a simulation of actuation of the component.

Abstract: Systems and methods for detecting degradation and failures, include types of failures, in a hose assembly are disclosed. One system includes a hose degradation monitoring circuit having a hose assembly including a hose having first and second conductive layers, and a degradation monitoring circuit configured to detect a resistance of the hose across the conductive layers. The degradation monitoring circuit includes a voltage source electrically connected to the first conductive layer, and a resistor electrically connected between the second conductive layer and ground. The degradation monitoring circuit further includes a voltage monitoring circuit electrically connected between the resistor and the second conductive layer, to periodically monitor a voltage at the location and detect a possible failure of the hose assembly upon determining that, based at least in part on a change in the voltage at the location over time, a resistance of the hose assembly has passed a threshold level.

Abstract: Some embodiments of the present BOP control systems include a system controller configured to actuate a first BOP function by communicating one or more commands to one or more nodes of a functional pathway selected from one or more available functional pathways associated with the first BOP function, each node comprising an actuatable component configured to actuate in response to a command received from the system controller, each node having one or more sensors configured to capture a first data set corresponding to actuation of the component and a processor configured to analyze the first data set to determine a useful life remaining of the component and/or compare the first data set to a second data set corresponding to a simulation of actuation of the component.

Abstract: A subsea processor may be located near the seabed of a drilling site and used to coordinate operations of underwater drilling components. The subsea processor may be enclosed in a single interchangeable unit that fits a receptor on an underwater drilling component, such as a blow-out preventer (BOP). The subsea processor may issue commands to control the BOP and receive measurements from sensors located throughout the BOP. A shared communications bus may interconnect the subsea processor and underwater components and the subsea processor and a surface or onshore network. The shared communications bus may be operated according to a time division multiple access (TDMA) scheme.

Abstract: Systems and methods for detecting degradation and failures, include types of failures, in a hose assembly are disclosed. One system includes a hose degradation monitoring circuit having a hose assembly including a hose having first and second conductive layers, and a degradation monitoring circuit configured to detect a resistance of the hose across the conductive layers. The degradation monitoring circuit includes a voltage source electrically connected to the first conductive layer, and a resistor electrically connected between the second conductive layer and ground. The degradation monitoring circuit further includes a voltage monitoring circuit electrically connected between the resistor and the second conductive layer, to periodically monitor a voltage at the location and detect a possible failure of the hose assembly upon determining that, based at least in part on a change in the voltage at the location over time, a resistance of the hose assembly has passed a threshold level.

Abstract: This disclosure includes subsea pumping apparatuses and related methods. Some apparatuses include one or more subsea pumps, each having an inlet and an outlet, and one or more motors, each configured to actuate at least one pump to communicate a hydraulic fluid from the inlet to the outlet, where the subsea pumping apparatus is configured to be in fluid communication with a hydraulically actuated device of a blowout preventer. Some subsea pumping apparatuses include one or more of: a desalination system configured to produce at least a portion of the hydraulic fluid; one or more valves, each configured to selectively route hydraulic fluid from an outlet of a pump to, for example, a subsea environment, a reservoir, and/or the inlet of the pump; and a reservoir configured to store at least a portion of the hydraulic fluid. Some apparatuses are configured to be directly coupled to the hydraulically actuated device.

Abstract: This disclosure includes BOP control and/or power and/or data communication systems and related methods. Some systems use or include a plurality of controllers, each in communication with a BOP control network and configured to transmit information associated with the BOP, and a signal conditioning circuit in electrical communication with and configured to provide a power signal and a data signal to at least one of the plurality of controllers, the signal conditioning circuit including a signal coupler, a subsea signal decoupler, an amplifier, and/or a frequency converter, where each controller is in communication with one or more processors and is configured to transmit at least a portion of the information through the BOP control network during a respective time interval.

Abstract: Systems and methods for print head calibration. In an exemplary embodiment, the method may include scanning an image on a print media to obtain an optical density profile. The method may also include selecting at least one window in the optical density profile. The method may also include generating an average profile for each window. The method may also include identifying variations in uniformity.

Abstract: A subsea processor may be located near the seabed of a drilling site and used to coordinate operations of underwater drilling components. The subsea processor may be enclosed in a single interchangeable unit that fits a receptor on an underwater drilling component, such as a blow-out preventer (BOP). The subsea processor may issue commands to control the BOP and receive measurements from sensors located throughout the BOP. A shared communications bus may interconnect the subsea processor and underwater components and the subsea processor and a surface or onshore network. The shared communications bus may be operated according to a time division multiple access (TDMA) scheme.

Abstract: A subsea processor may be located near the seabed of a drilling site and used to coordinate operations of underwater drilling components. The subsea processor may be enclosed in a single interchangeable unit that fits a receptor on an underwater drilling component, such as a blow-out preventer (BOP). The subsea processor may issue commands to control the BOP and receive measurements from sensors located throughout the BOP. The subsea processor may relay information to the surface for recording or monitoring. The subsea processor may also be programmed with a model from which to base operation of the BOP, such as in emergency conditions.

Abstract: A filter for edible oil and fat designed to increase the useful life of oil and fat used for frying foodstuff and to improve the quality thereof, having reduced shape and dimensions, thus allowing to be immersed in the oil to be filtered, thus eliminating the time spent for removing and conveying the hot oil compared to the traditional filtering methods and making the process safer; the shorter time reducing the loss of heat, thus keeping the oil hot and the viscosity low and thus facilitating the passage thereof through filtering element.