Patents by Inventor Luisa W Cheng

Luisa W Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity monoclonal antibodies for detecting amanitins
    Patent number: 11802147
    Abstract: Amatoxins (AMAs) are lethal toxins found in a variety of mushroom species. Detection methods are needed to determine the occurrence of AMAs in mushroom species, often suspected in mushroom poisonings. Provided herein are novel, sensitive monoclonal antibodies (mAbs) detection and purification techniques utilizing the mAbs that show selectivity for ?-amanitin (?-AMA), ?-amanitin (?-AMA) and ?-amanitin (?-AMA).
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: October 31, 2023
    Assignee: The United States of America, as represented by The Secretary of Agriculture
    Inventors: Candace R. Bever, Larry H. Stanker, Robert M. Hnasko, Luisa W. Cheng
  • HIGH AFFINITY MONOCLONAL ANTIBODIES FOR DETECTING AMANITINS
    Publication number: 20210002357
    Abstract: Amatoxins (AMAs) are lethal toxins found in a variety of mushroom species. Detection methods are needed to determine the occurrence of AMAs in mushroom species, often suspected in mushroom poisonings. Provided herein are novel, sensitive monoclonal antibodies (mAbs) detection and purification techniques utilizing the mAbs that show selectivity for ?-amanitin (?-AMA), ?-amanitin (?-AMA) and ?-amanitin (?-AMA).
    Type: Application
    Filed: June 19, 2020
    Publication date: January 7, 2021
    Inventors: Candace R. Bever, Larry H. Stanker, Robert M. Hnasko, Luisa W. Cheng
  • High affinity monoclonal antibodies for detection of Shiga toxin 2 (STX2)
    Patent number: 9310368
    Abstract: High affinity monoclonal antibodies against Stx2 and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting Stx2 and variants thereof in a sample as well as neutralization of Shiga toxin in vivo.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: April 12, 2016
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Xiaohua He, Larry H. Stanker, Luisa W. Cheng
  • High-affinity monoclonal antibodies for botulinum toxin type B
    Patent number: 9145455
    Abstract: High affinity antibodies for binding epitopes of BoNT/B and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/B in a sample.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: September 29, 2015
    Assignee: The United States of America, as represented by The Secretary of Agriculture
    Inventors: Larry H. Stanker, Miles C. Scotcher, Luisa W. Cheng, Robert M. Hnasko, Jeffery A. McGarvey
  • HIGH-AFFINITY MONOCLONAL ANTIBODIES FOR BOTULINUM TOXIN TYPE B
    Publication number: 20150152168
    Abstract: High affinity antibodies for binding epitopes of BoNT/B and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/B in a sample.
    Type: Application
    Filed: October 20, 2014
    Publication date: June 4, 2015
    Inventors: Larry H. Stanker, Miles C. Scotcher, Luisa W. Cheng, Robert M. Hnasko, Jeffery A. McGarvey
  • High-affinity monoclonal antibodies for botulinum toxin type B
    Patent number: 8900824
    Abstract: High affinity antibodies for binding epitopes of BoNT/B and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/B in a sample.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: December 2, 2014
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Larry H. Stanker, Miles C. Scotcher, Luisa W. Cheng, Robert M. Hnasko, Jeffery A. McGarvey
  • High-affinity monoclonal antibodies for botulinum toxin type A
    Patent number: 7732579
    Abstract: High affinity antibodies for binding epitopes of BoNT/Aand hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/A in a sample.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: June 8, 2010
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Larry H Stanker, Luisa W Cheng, Miles C Scotcher
  • High-Affinity Monoclonal Antibodies for Botulinum Toxin Type A
    Publication number: 20090117587
    Abstract: High affinity antibodies for binding epitopes of BoNT/A and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/A in a sample.
    Type: Application
    Filed: June 13, 2008
    Publication date: May 7, 2009
    Applicant: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Larry H. Stanker, Luisa W. Cheng, Miles C. Scotcher