Patents by Inventor Luisella Bonomini

Luisella Bonomini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridopyrimidinones derivatives as telomerase inhibitors
    Patent number: 7019002
    Abstract: The invention provides pyrido[2,3-d]pyrimidin-7(8H)-one telomerase inhibitors of the formula where R1, R2 are as defined herein. The invention also provides methods for preparing the compounds of formula I, methods of using the compounds to treat diseases such as cancer, and pharmaceutical compositions comprising the compounds.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: March 28, 2006
    Assignee: Pharmacia & Upjohn, S.p.A.
    Inventors: Mauro Angiolini, Dario Ballinari, Domenico Fusar Bassini, Luisella Bonomini, Markus Gude, Maria Menichincheri, Jurgen Moll, Jean-Yves Trosset
  • Disubstituted 7,9-guanines halides as telomerase inhibitors
    Publication number: 20050037990
    Abstract: The present invention relates to benzylmethyl and/or naphtylmethyl disubstituted 7,9-guaninium halides possessing antitumor activity, to pharmaceutical compositions comprising them and to a process for preparing the same. Furthermore, those compounds are expected to enhance the efficacy of other chemotherapeutic agents, in the treatment of cancer.
    Type: Application
    Filed: June 8, 2001
    Publication date: February 17, 2005
    Inventors: Alberto Bargiotti, Antonella Ermoli, Maria Menichincheri, Ermes Vanotti, Luisella Bonomini, Antonella Fretta
  • Disubstituted 1,7-guanines
    Publication number: 20040138212
    Abstract: The present invention relates to 1,7 disubstituted guanines inhibitors possessing antitumor activity and to a process for preparing the same. Furthermore, these compounds are expected to enhance the efficacy of other chemotherapeutic agents, in the treatment of cancer.
    Type: Application
    Filed: March 15, 2004
    Publication date: July 15, 2004
    Inventors: Alberto Bargiotti, Antonella Ermoli, Maria Menichincheri, Ermes Vanotti, Luisella Bonomini, Antonella Fretta
  • Aurones as telomerase inhibitors
    Publication number: 20040132807
    Abstract: The present invention relates to know and novel substituted aurones active as telomerase inhibitors, to their use as therapeutic agents, in particular as antitumoral agents, to a process for their preparation as to pharmaceutical compositions comprising them.
    Type: Application
    Filed: October 17, 2003
    Publication date: July 8, 2004
    Inventors: Dario Ballinari, Luisella Bonomini, Antonella Ermoli, Markus Gude, Maria Menichincheri, Jurgen Moll, Ermes Vanotti
  • Substituted benzopyranones as telomerase inhibitors
    Publication number: 20040063665
    Abstract: The present invention relates to benzopyranone derivative, to methods for treating telomerase-modulated diseases, in particular cancers, with said derivatives, to a process for their preparation, to their use as medicaments and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: September 16, 2003
    Publication date: April 1, 2004
    Inventors: Alberto Bargiotti, Luisella Bonomini, Maria Menichincheri, Jurgen Moll, Paolo Polucci, Chiara Soncini, Ermes Vanotti
  • Pyridopyrimidinones derivatives as telomerase inhibitors
    Publication number: 20040009993
    Abstract: The invention provides novel pyrido[2,3-d]pyrimidin-7(8H)-ones derivatives active as telomerase inhibitors, the use of the derivatives as therapeutic agents, such as antitumoral agents, processes for preparation of the derivatives, and to pharmaceutical compositions comprising the derivatives.
    Type: Application
    Filed: December 4, 2002
    Publication date: January 15, 2004
    Applicant: Pharmacia Italia S.p.A.
    Inventors: Mauro Angiolini, Dario Ballinari, Domenico Fusar Bassini, Luisella Bonomini, Markus Gude, Maria Menichincheri, Jurgen Moll, Jean-Yves Trosset
  • Novel telomerase inhibitors
    Publication number: 20030186978
    Abstract: The present invention relates to novel telomerase inhibitors possessing antitumor activity and to a process for preparing the same. Furthermore, these compounds enhance the efficacy of other chemotherapeutic agents, in the treatment of cancer.
    Type: Application
    Filed: May 23, 2003
    Publication date: October 2, 2003
    Inventors: Alberto Bargiotti, Antonella Ermoli, Maria Menichincheri, Ermes Vanotti, Luisella Bonomini, Antonella Fretta
  • Substituted benzopyranones as telomerase inhibitors
    Publication number: 20020160983
    Abstract: The present invention relates to benzopyranone derivatives, to methods for treating telomerase-modulated diseases, in particular cancers, with said derivatives, to a process for their preparation, to their use as medicaments and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: March 16, 2001
    Publication date: October 31, 2002
    Inventors: Alberto Bargiotti, Luisella Bonomini, Maria Menichincheri, Jurgen Moll, Paolo Polucci, Chiara Soncini, Ermes Vanotti