Patents by Inventor Lujue LONG

Lujue LONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250041387
    Abstract: Disclosed in the present invention is an application of lysine (K)-specific demethylase 6B (KDM6B) in regulating and controlling the function of a mesenchymal stem cell. WDR5 is a co-binding protein for negatively regulating and controlling the functions of KDM6B and the MLL1. WDR5 can form a protein complex with KDM6B to inhibit the function of KDM6B, such that expression and functions of genes are regulated and controlled by regulating and controlling the methylation state of downstream senescence and osteogenesis related genes and gene promoter region histone, and finally the effects of regulating stem cell senescence and differentiation functions and bone/tooth tissue repair and regeneration functions are achieved. For a KDM6B and WDR5 binding region sequence, small-molecule polypeptide is researched, developed, and utilized, and the function of the mesenchymal stem cell is regulated by regulating and controlling the binding of a KDM6B/WDR5 complex.
    Type: Application
    Filed: November 30, 2021
    Publication date: February 6, 2025
    Applicant: BEIJING STOMATOLOGICAL HOSPITAL, CAPITAL MEDICAL UNIVERSITY
    Inventors: Zhipeng FAN, Chen ZHANG, Yu JIANG, Lujue LONG, Yangyang CAO