Abstract: This invention relates to novel dibenzo[d,g][1,3,6]dioxazocine derivatives represented by the general formula I ##STR1## wherein R.sub.1 and R.sub.2 independently represent hydrogen, halogen, cyano or trifluoromethyl,Y stands for hydrogen or a group of formula ##STR2## wherein A stands for a straight or branched chained alkylene having from 2 to 5 carbon atoms andR.sub.3 and R.sub.4 independently stand for an alkyl having from 1 to 4 carbon atoms, orR.sub.3 and R.sub.4 together with the nitrogen atom they are attached to and optionally together with a further nitrogen atom or with an additional oxygen atom may form a five- or six-membered heterocyclic ring optionally substituted with an alkyl having from 1 to 4 carbon atoms,and pharmaceutically acceptable acid addition salts thereof formed with an inorganic or organic acid.A process for the preparation of these compounds is also within the scope of this invention.

Abstract: This invention relates to novel dibenzo[d,g][1,3,6]dioxazocine derivatives represented by the general formula I ##STR1## wherein R.sub.1 and R.sub.2 independently represent hydrogen, halogen, cyano or trifluoromethyl,Y stands for hydrogen or a group of formula ##STR2## wherein A stands for a straight or branched chained alkylene having from 2 to 5 carbon atoms andR.sub.3 and R.sub.4 independently stand for an alkyl having from 1 to 4 carbon atoms, orR.sub.3 and R.sub.4 together with the nitrogen atom they are attached to and optionally together with a further nitrogen atom or with an additional oxygen atom may form a five- or six-membered heterocyclic ring optionally substituted with an alkyl having from 1 to 4 carbon atoms,and pharmaceutically acceptable acid addition salts thereof formed with an inorganic or organic acid.The above compounds possess valuable pharmaceutical properties, for instance they are effective local anaesthetics and can be used for treating Parkinson syndrome.

Abstract: The invention relates to novel nortropine-carbazate derivatives of the general formula (I), ##STR1## wherein R.sub.1 is C.sub.1-4 alkyl, phenyl or halophenyl group,R.sub.2 is hydrogen or a C.sub.1-4 alkyl, hydroxy-C.sub.1-4 alkyl, C.sub.1-4 acyl, phenoxycarbonyl or C.sub.1-4 alkoxycarbonyl group, andR.sub.3 is hydrogen of a C.sub.1-4 alkyl or C.sub.1-4 acyl group, orR.sub.2 and R.sub.3 may form together a C.sub.1-10 alkylene group attachedTo the nitrogen atom with a double bond, as well as to pharmaceutically acceptable acid addition salts of said compounds.The above compounds are new and can be applied as narcosis potentiating agents.The compounds of the general formula (I) can be prepared by reacting a compound of the general formula (II), ##STR2## wherein R.sub.1 is as defined above and Q is halogen, C.sub.1-4 alkoxy or phenoxy, with a hydrazine compound of the general formula (III), ##STR3## wherein R.sub.2 and R.sub.3 are as defined above.

Abstract: Pharmaceutical compositions for the treatment of Parkinson's Disease contain 5-(1-methylpiperidylidene-4-5H-dibenzo(a,d)cycloheptene or a pharmaceutically acceptable salt thereof and L-3,4-dihydroxyphenylalanine or a pharmaceutically acceptable salt thereof in a weight ratio of 0.5-5 : 50-150, optionally together with a carrier.

Abstract: New compounds of the general formula (I) ##SPC1##and salts thereof were prepared by reacting a compound of the general formula (II) ##SPC2##with a compound of the general formula (III) or (IV) ##EQU1## and optionally saturating the --C=N-- bond. In the above formulaeR.sup.1 and R.sup.2 are always the same and represent a C.sub.1-4 alkyl group,R.sup.3 stands for hydrogen,R.sup.4 and R.sup.5 each represent hydrogen or a straight-chained or branched C.sub.1-16 alkyl group optionally having an unsubstituted or substituted phenyl, furyl or naphthyl substituent, wherein said substituted aryl groups may contain up to 3 alkyl, C.sub.1-3 alkoxy, benzyloxy, nitro, amino, lower alkylamino, di-lower alkylamino, methylenedioxy, alkylmercapto, alkylsulfonyl or halogen substituents, orR.sup.4 and R.sup.5 may form together with the adjacent carbon atom a C.sub.3-12 cycloalkyl or C.sub.